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List of works by Alessandro Carugo

Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies

scientific article published on 30 November 2021

Collapsing the Tumor Ecosystem: Preventing Adaptive Response to Treatment by Inhibiting Transcription.

scientific article published in January 2018

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

scientific article published on 01 January 2019

Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer

scientific article published on 3 March 2015

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

scientific article published in Nature Communications

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

scientific article

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

scientific article published on 05 April 2018

In Vivo Functional Platform Targeting Patient-Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer.

scientific article published on 16 June 2016

Loss of ARID1A promotes epithelial-mesenchymal transition and sensitizes pancreatic tumors to proteotoxic stress

scientific article published on 06 November 2020

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

scientific article published on 26 May 2021

Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.

scientific article published on 2 April 2019

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

scientific article

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

scientific article published on 30 July 2021

Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors

scientific article published on 01 February 2019

RNAi screens identify CHD4 as an essential gene in breast cancer growth

scientific article

Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state

scientific article published on 01 April 2019

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

scientific article published on 27 March 2019

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

scientific article published on 8 February 2017

Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition

scientific article published on 11 June 2021

Targeting proteostasis and autophagy in SMARCB1-deficient malignancies: where next?

scientific article published on 18 June 2019

The Many Facets of Tumor Heterogeneity: Is Metabolism Lagging Behind?

scientific article published on 16 October 2019

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism

scientific article published on 01 March 2019

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

scientific article published on 01 February 2019

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