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List of works by Guang-Hui Liu

A chemical approach to "rewire" neural progenitor cells

scientific article published on 18 April 2014

A cut above the rest: targeted genome editing technologies in human pluripotent stem cells

scientific article published on 20 December 2013

A genome-wide CRISPR-based screen identifies <i>KAT7</i> as a driver of cellular senescence

scientific article published on 01 January 2021

A human circulating immune cell landscape in aging and COVID-19

scientific article published on 11 August 2020

A novel suppressive effect of alcohol dehydrogenase 5 in neuronal differentiation

scientific article

A single-cell transcriptomic landscape of primate arterial aging

scientific article published on 05 May 2020

A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells

scientific article published on May 2015

A β-galactosidase kiss of death for senescent cells

scientific article published on 04 May 2020

ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells

scientific article published on 13 July 2020

ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells

scientific article published on 5 January 2018

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

scientific article published on 30 April 2015

Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice

scientific article published on 08 November 2021

Autophagic control of cell ‘stemness’ ⬇️

scientific article published on March 1, 2013

BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates

scientific article published on 01 April 2022

Beating in a dish: new hopes for cardiomyocyte regeneration

scientific article published on 27 November 2012

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.

scientific article

Chemical screen identifies a geroprotective role of quercetin in premature aging

scientific article published on 01 August 2018

Concealing cellular defects in pluripotent stem cells ⬇️

scientific article published on August 1, 2013

Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc

scientific article

Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

scientific article published in 2022

Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor

scientific article published on 01 February 2022

Cut and paste: restoring cellular function by gene correction

scientific article

Deciphering primate retinal aging at single-cell resolution

scientific article published on 14 October 2020

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

scientific article published on 23 February 2018

Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors

scientific article published on 29 January 2014

Direct reprogramming of porcine fibroblasts to neural progenitor cells

scientific article published on January 2014

Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model

scientific article published on 11 September 2018

Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs

scientific article published on 22 November 2011

Establishment of hepatic and neural differentiation platforms of Wilson’s disease specific induced pluripotent stem cells ⬇️

scientific article published on July 18, 2012

Gametogenesis in a dish

scientific article

Gating neural development and aging via nuclear pores ⬇️

scientific article published on March 13, 2012

Gating pluripotency via nuclear pores

scientific article

Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding

scientific article

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

scientific article

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy ⬇️

scientific article published on March 22, 2012

Huntington's disease: Dancing in a dish ⬇️

scientific article published on August 7, 2012

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

scientific article

Induced neural stem cells: a new tool for studying neural development and neurological disorders

scientific article

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.

scientific article published on 6 September 2017

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

scientific article published on 18 July 2020

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7

scientific article published on 16 April 2018

Mitochondrial Regulation in Pluripotent Stem Cells ⬇️

scientific article published on July 11, 2013

Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

scientific article published on 13 February 2016

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

scientific article

Navigating the epigenetic landscape of pluripotent stem cells ⬇️

scientific article published on July 23, 2012

New march towards the regeneration of sensation and cognition: hear more, see more and learn more ⬇️

scientific article published on 06 December 2012

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

scientific article

Post-translational modulation of pluripotency ⬇️

scientific article published on 07 June 2012

Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction

scientific article published on 23 August 2019

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

scientific article

Protein quality control of cell stemness

scientific article published on 12 November 2020

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

scientific article

Regeneration: making muscle from hPSCs

scientific article published on 8 July 2014

Regenerative medicine: targeted genome editing in vivo

scientific article

Regenerative medicine: transdifferentiation in vivo

scientific article published on 17 December 2013

Regulation of Stem Cell Aging by Metabolism and Epigenetics

scientific article

Rejuvenating liver and pancreas through cell transdifferentiation ⬇️

scientific article published on February 28, 2012

Reprogramming based gene therapy for inherited red blood cell disorders ⬇️

scientific article published on April 3, 2012

SIRT3 consolidates heterochromatin and counteracts senescence

scientific article published on 01 May 2021

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

scientific article published on 06 June 2020

Selective elimination of mitochondrial mutations in the germline by genome editing

scientific article

Single-cell omics in ageing: a young and growing field

scientific article published on 20 April 2020

Single-cell transcriptomic atlas of primate cardiopulmonary aging

scientific article published on 10 September 2020

Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration

scientific article published on 31 July 2020

Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis

scientific article published on 26 July 2019

Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome

scientific article published on 28 January 2020

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs

scientific article

The ageing epigenome and its rejuvenation

scientific article published on 04 February 2020

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells ⬇️

scientific article published on September 11, 2012

Treating osteoarthritis via gene therapy with rejuvenation factors

scientific article published on 27 April 2020

Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis

scientific article published on 01 April 2019

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing

scientific article published on 25 June 2022

hESC-derived pancreatic progenitors ⬇️

scientific article published on February 5, 2013

iPSC technology to study human aging and aging-related disorders ⬇️

scientific article published on September 18, 2012

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells

scientific article published in 2022

αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model

scientific article published on 01 March 2020

“TET-on” pluripotency ⬇️

scientific article published on June 4, 2013

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