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List of works by Jaime Santo-Domingo

A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells.

scientific article

Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

scientific article

Antibiotics induce mitonuclear protein imbalance but fail to inhibit respiration and nutrient activation in pancreatic β-cells.

scientific article published on 17 May 2017

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

scientific article published on 22 September 2020

Cellular stress is a prerequisite for glucose-induced mitochondrial matrix alkalinization in pancreatic β-cells

scientific article published on 23 November 2018

Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells

scientific article published on 07 December 2016

Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids

scientific article published on November 2004

Glucose-dependent phosphorylation signaling pathways and crosstalk to mitochondrial respiration in insulin secreting cells

scientific article published on 20 February 2019

L-OPA1 regulates mitoflash biogenesis independently from membrane fusion.

scientific article published on 07 February 2017

Mitochondrial ion channels in pancreatic β-cells: Novel pharmacological targets for the treatment of Type 2 diabetes

scientific article published on 13 February 2020

Modulation of the matrix redox signaling by mitochondrial Ca(2.)

scientific article

NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state

scientific article

OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange

scientific article

Protein Lysine Acetylation: Grease or Sand in the Gears of β-Cell Mitochondria?

scientific article published on 16 October 2019

Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release from the endoplasmic reticulum by AMP-activated kinase modulators

scientific article published on 11 December 2018

Securin and Separase Modulate Membrane Traffic by Affecting Endosomal Acidification ⬇️

scientific article published on February 25, 2011

Targeting mitochondrial ion channels in Type 2 diabetes

scientific article published on 23 July 2020

The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells

scientific article published on 15 July 2019

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