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List of works by Jeffry S. Nyman

30-Second bound and pore water concentration mapping of cortical bone using 2D UTE with optimized half-pulses

scientific article

A novel approach to assess post-yield energy dissipation of bone in tension

scientific article

A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration

scientific article published in July 2010

A targeted approach for evaluating preclinical activity of botanical extracts for support of bone health

scientific article

A theoretical analysis of long-term bisphosphonate effects on trabecular bone volume and microdamage

scientific article published in July 2004

Advances in imaging approaches to fracture risk evaluation

scientific article

Age-related changes in the fracture resistance of male Fischer F344 rat bone

scientific article

Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue.

scientific article published on 8 September 2006

Age-related factors affecting the postyield energy dissipation of human cortical bone

scientific article

Anti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to bone

scientific article (publication date: 2011)

Applying Full Spectrum Analysis to a Raman Spectroscopic Assessment of Fracture Toughness of Human Cortical Bone

scientific article published in January 2017

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

scientific article

Assessing glycation-mediated changes in human cortical bone with Raman spectroscopy

scientific article published on 06 May 2018

Assessing matrix quality by Raman spectroscopy helps predict fracture toughness of human cortical bone

scientific article published on 10 May 2019

Autologous chondrocyte grafting promotes bone formation in the posterolateral spine

scientific article published on 23 March 2018

Biomechanical evaluation of physeal-sparing fixation methods in tibial eminence fractures

scientific article published on 20 May 2013

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells.

scientific article

Bone Fracture Acute Phase Response-A Unifying Theory of Fracture Repair: Clinical and Scientific Implications.

scientific article published on 29 December 2018

Bone collagen network integrity and transverse fracture toughness of human cortical bone

scientific article published on 28 October 2018

Canagliflozin, an SGLT2 inhibitor, corrects glycemic dysregulation in TallyHO model of T2D but only partially prevents bone deficits

scientific article published on 02 September 2020

Changes in the Fracture Resistance of Bone with the Progression of Type 2 Diabetes in the ZDSD Rat.

scientific article published on 21 May 2016

Characterization of 1H NMR signal in human cortical bone for magnetic resonance imaging.

scientific article

Clinically compatible MRI strategies for discriminating bound and pore water in cortical bone

scientific article

Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1Osx -/- mice

scientific article

Combined treatment with a transforming growth factor beta inhibitor (1D11) and bortezomib improves bone architecture in a mouse model of myeloma-induced bone disease

scientific article published on 13 July 2016

Compressive fatigue and fracture toughness behavior of injectable, settable bone cements

scientific article

Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization

scientific article published on 02 November 2019

Corrigendum to "SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice" [Bone 82 (2016) 101-107]

scientific article published on 29 November 2016

Cortical bone mechanical properties are altered in an animal model of progressive chronic kidney disease

scientific article

Daily parathyroid hormone administration enhances bone turnover and preserves bone structure after severe immobilization-induced bone loss

scientific article published on 27 September 2017

Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy

scientific article published on 31 May 2016

Development of Raman spectral markers to assess metastatic bone in breast cancer

scientific article

Differences in sensitivity to microstructure between cyclic- and impact-based microindentation of human cortical bone

scientific article published on 4 October 2016

Differences in the mechanical behavior of cortical bone between compression and tension when subjected to progressive loading.

scientific article published on 13 December 2008

Differential development of the distal and proximal femoral epiphysis and physis in mice

scientific article published on 15 October 2012

Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone

scientific article published in June 2011

Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity

scientific article

Effect of mixing method on selected properties of acrylic bone cement ⬇️

scientific article published on 01 January 1997

Effect of ultrastructural changes on the toughness of bone

scientific article

Effects of long-term doxycycline on bone quality and strength in diabetic male DBA/2J mice

scientific article

Erratum: Corrigendum: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1

scientific article published on 01 April 2015

Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis

scientific article published on 04 September 2013

Fibrin accumulation secondary to loss of plasmin-mediated fibrinolysis drives inflammatory osteoporosis in mice

scientific article published on August 2014

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification

scientific article published on 27 July 2015

Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification

scientific article published in September 2015

Finite element analysis of bone mechanical properties using MRI-derived bound and pore water concentration maps

scientific article published in 2022

Fracture healing in protease-activated receptor-2 deficient mice

scientific article published on 13 January 2012

Genetic ablation of SGLT2 function in mice impairs tissue mineral density but does not affect fracture resistance of bone

scientific article published on 25 January 2020

Identifying Novel Clinical Surrogates to Assess Human Bone Fracture Toughness

scientific article

In Vivo Quantitative MR Imaging of Bound and Pore Water in Cortical Bone

scientific article

In Vivo Quantitative MR Imaging of Bound and Pore Water in Cortical Bone

scientific article published on 01 December 2015

Increasing duration of type 1 diabetes perturbs the strength-structure relationship and increases brittleness of bone

scientific article

Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo

scientific article published on 01 November 2010

Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior

scientific article

Integrated system for combined Raman spectroscopy-spectral domain optical coherence tomography

scientific article

Local application of a proteasome inhibitor enhances fracture healing in rats

scientific article published on 25 May 2015

Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.

scientific article

Long stemmed total knee arthroplasty with interlocking screws: a computational bone adaptation study

scientific article published in January 2004

Loss of insulin receptor in osteoprogenitor cells impairs structural strength of bone.

scientific article

Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.

scientific article published on 10 February 2018

MRI-derived bound and pore water concentrations as predictors of fracture resistance

scientific article

Manipulating the Amount and Structure of the Organic Matrix Affects the Water Compartments of Human Cortical Bone

scientific article published on 28 January 2019

Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone

scientific article

Measuring differences in compositional properties of bone tissue by confocal Raman spectroscopy

scientific article published on 20 May 2011

Mechanical behavior of human cortical bone in cycles of advancing tensile strain for two age groups

scientific article

Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.

scientific article

Micro-computed tomography assessment of the progression of fracture healing in mice

scientific article published on 17 March 2012

Micro-computed tomography derived anisotropy detects tumor provoked deviations in bone in an orthotopic osteosarcoma murine model

scientific article

N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder

scientific article published on 23 March 2020

Nanocrystalline hydroxyapatite-poly(thioketal urethane) nanocomposites stimulate a combined intramembranous and endochondral ossification response in rabbits

scientific article published on 10 December 2019

Non-invasive predictors of human cortical bone mechanical properties: T(2)-discriminated H NMR compared with high resolution X-ray

scientific article (publication date: 21 January 2011)

Osteo-promoting effects of insulin-like growth factor I (IGF-I) in a mouse model of type 1 diabetes

scientific article published on 23 July 2013

Partial removal of pore and loosely bound water by low-energy drying decreases cortical bone toughness in young and old donors

scientific article

Polarization control of Raman spectroscopy optimizes the assessment of bone tissue

scientific article published on May 2013

Polarization in Raman spectroscopy helps explain bone brittleness in genetic mouse models

scientific article

Post-translational modifications in collagen type I of bone in a mouse model of aging

scientific article published on 18 November 2020

Predicting mouse vertebra strength with micro-computed tomography-derived finite element analysis.

scientific article

Predictions on preserving bone mass in knee arthroplasty with bisphosphonates

scientific article published in January 2006

Preserving and restoring bone with continuous insulin infusion therapy in a mouse model of type 1 diabetes.

scientific article

Prevalent role of porosity and osteonal area over mineralization heterogeneity in the fracture toughness of human cortical bone

scientific article published on 15 June 2016

Prostate cancer metastases alter bone mineral and matrix composition independent of effects on bone architecture in mice--a quantitative study using microCT and Raman spectroscopy

scientific article published on 15 July 2013

Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography

scientific article published on 17 March 2009

Raloxifene improves skeletal properties in an animal model of cystic chronic kidney disease

scientific article published on 21 October 2015

Raman and mechanical properties correlate at whole bone- and tissue-levels in a genetic mouse model

scientific article

Reactivation of a developmental signaling center is required for therapeutic control of the murine periosteal niche

scientific article published on 08 February 2019

SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice

scientific article

Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model

scientific article published on 26 June 2018

Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling

scientific article published on 01 April 2013

Synergistic effect of exercise and statins on femoral strength in rats

scientific article

Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit.

scientific article

The BALB/c mouse as a preclinical model of the age-related deterioration in the lumbar vertebra

scientific article published on 29 May 2020

The Role of Matrix Composition in the Mechanical Behavior of Bone.

scientific article

The Role of Water Compartments in the Material Properties of Cortical Bone

scientific article

The Size of Intramedullary Fixation Affects Endochondral-Mediated Angiogenesis During Fracture Repair

scientific article published on 01 October 2019

The age-related decrease in material properties of BALB/c mouse long bones involves alterations to the extracellular matrix

scientific article published on 31 October 2019

The apparent fracture toughness of acrylic bone cement: effect of three variables ⬇️

scientific article published on May 1, 1998

The contribution of the extracellular matrix to the fracture resistance of bone

scientific article published on June 2012

The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora

scientific article published on 17 September 2009

The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes.

scientific article

The influence of water removal on the strength and toughness of cortical bone.

scientific article published on January 2006

The loss of activating transcription factor 4 (ATF4) reduces bone toughness and fracture toughness

scientific article

The temporal and spatial development of vascularity in a healing displaced fracture.

scientific article published on 10 July 2014

The use of nanoindentation for characterizing the properties of mineralized hard tissues: state-of-the art review

scientific article published on October 2008

Tissue-Level Mechanical Properties of Bone Contributing to Fracture Risk

scientific article published on 4 June 2016

Transdermal lovastatin enhances fracture repair in rats

scientific article

Transforming growth factor β suppresses osteoblast differentiation via the vimentin activating transcription factor 4 (ATF4) axis

scientific article published on 4 September 2012

Type 1 diabetes in young rats leads to progressive trabecular bone loss, cessation of cortical bone growth, and diminished whole bone strength and fatigue life

scientific article published on September 2009

Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice.

scientific article published on 31 May 2018

Validation of quantitative bound- and pore-water imaging in cortical bone

scientific article

β2-Adrenergic receptor signaling in osteoblasts contributes to the catabolic effect of glucocorticoids on bone

scientific article

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