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List of works by Osamu Miura

A novel MYD88 mutation, L265RPP, in Waldenström macroglobulinemia activates the NF-κB pathway to upregulate Bcl-xL expression and enhances cell survival.

scientific article published on 15 May 2015

Acute myeloid leukemia with t(3;21)(q26.2;q22) developing following low-dose methotrexate therapy for rheumatoid arthritis and expressing two AML1/MDS1/EVI1 fusion proteins: A case report.

scientific article published on 10 May 2017

Atypical chronic myeloid leukemia with isochromosome (X)(p10): A case report.

scientific article published on 18 July 2017

CD137 Is Induced by the CD40 Signal on Chronic Lymphocytic Leukemia B Cells and Transduces the Survival Signal via NF-κB Activation ⬇️

scientific article published on May 16, 2013

CD137 expression is induced by Epstein-Barr virus infection through LMP1 in T or NK cells and mediates survival promoting signals

scientific article

CD79B mutations in primary vitreoretinal lymphoma: Diagnostic and prognostic potential

scientific article published on 23 November 2018

Clinical features of adult-onset chronic active Epstein–Barr virus infection: a retrospective analysis ⬇️

scientific article published on April 14, 2011

Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study

scientific article published on 22 January 2015

Cord blood transplantation is associated with rapid B-cell neogenesis compared with BM transplantation

scientific article published on 30 June 2014

Correction: EBV induces persistent NF-κB activation and contributes to survival of EBV-positive neoplastic T- or NK-cells.

scientific article published on August 2017

DNA Damage Stress and Inhibition of Jak2-V617F Cause Its Degradation and Synergistically Induce Apoptosis through Activation of GSK3β ⬇️

scientific article published on November 8, 2011

Development of Extranodal NK/T-cell Lymphoma Nasal Type in Cerebrum Following Epstein-Barr Virus-positive Uveitis.

scientific article

Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells.

scientific article

Dual inhibition of EZH1/2 over-activates WNT signaling to deplete cancer stem cells in multiple myeloma

article

EBV induces persistent NF-κB activation and contributes to survival of EBV-positive neoplastic T- or NK-cells.

scientific article

Erythropoietin and IL-3 Induce Tyrosine Phosphorylation of CrkL and Its Association with Shc, SHP-2, and Cbl in Hematopoietic Cells ⬇️

scientific article published on October 20, 1997

FDG-PET/CT findings of chronic active Epstein-Barr virus infection

scientific article published on 12 October 2017

FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM

scientific article published on 20 November 2019

FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia

scientific article

FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway.

scientific article published on 4 December 2017

Fatty acid beta oxidation enzyme HADHA is a novel potential therapeutic target in malignant lymphoma

scientific article published on 16 September 2019

Fulminant visceral disseminated varicella-zoster virus infection without skin involvement in a patient with autoimmune hemolytic anemia on prednisolone therapy

scientific article published on April 2016

Glutathione peroxidase 4 overexpression inhibits ROS-induced cell death in diffuse large B-cell lymphoma

scientific article published on 20 February 2018

Hematopoietic stem cell transplantation for adults with EBV-positive T- or NK-cell lymphoproliferative disorders: efficacy and predictive markers

scientific article

High-dose methotrexate following intravitreal methotrexate administration in preventing central nervous system involvement of primary intraocular lymphoma

scientific article published on 14 July 2016

High-resolution genomic copy number profiling of primary intraocular lymphoma by single nucleotide polymorphism microarrays.

scientific article

Immune-mediated neuropathy with Epstein-Barr virus-positive T-cell lymphoproliferative disease

scientific article published on January 2015

Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis ⬇️

scientific article published on October 1, 1991

Infectious mononucleosis accompanied by clonal proliferation of EBV-infected cells and infection of CD8-positive cells.

scientific article published on 19 March 2014

Inhibition of USP9X Downregulates JAK2-V617F and Induces Apoptosis Synergistically with BH3 Mimetics Preferentially in Ruxolitinib-Persistent JAK2-V617F-Positive Leukemic Cells

scientific article published on 10 February 2020

Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress

scientific article published on 01 April 2019

Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.

scientific article

Inhibition of the STAT5/Pim Kinase Axis Enhances Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive AML Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway

scientific article published on 22 November 2018

Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2.

scientific article

Methotrexate-associated Classical Hodgkin Lymphoma Shows Distinct Clinicopathological Features but Comparable Clinical Outcomes With Sporadic Cases

scientific article published on 01 September 2019

Methotrexate/iatrogenic lymphoproliferative disorders in rheumatoid arthritis: histology, Epstein–Barr virus, and clonality are important predictors of disease progression and regression ⬇️

scientific article published on May 13, 2013

Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1).

scientific article published on 3 October 2017

PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells ⬇️

scientific article published on December 6, 2012

Postoperative Atypical Hemolytic Uremic Syndrome Treated Successfully with Eculizumab.

scientific article

Prediction of Prognosis for Patients with Diffuse Large B-Cell Lymphoma Refractory to or in First Relapse After Initial R-CHOP Therapy: A Single-Institution Study

scientific article published in May 2017

Pregnancy outcomes of patients with paroxysmal nocturnal hemoglobinuria treated with eculizumab: a Japanese experience and updated review

scientific article published on 8 February 2016

Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera

scientific article published on 03 January 2014

SOCS-3 inhibits IL-12-induced STAT4 activation by binding through its SH2 domain to the STAT4 docking site in the IL-12 receptor β2 subunit ⬇️

scientific article (publication date: 31 October 2003)

STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target

scientific article published on 24 July 2018

Sequential monitoring of serum IL-6, TNF-α, and IFN-γ levels in a CAEBV patient treated by plasma exchange and immunochemotherapy ⬇️

scientific article published on September 16, 2012

Soluble Interleukin-2 Receptor Level at Diagnosis Predicts Prognosis of Patients With Follicular Lymphoma Irrespective of Initial Management Strategy

scientific article published on 01 September 2019

TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation

scientific article published on 05 March 2019

Therapy-related leukemia with Inv(16)(p13.1q22) and type D CBFB/MYH11 developing after exposure to irinotecan-containing chemoradiotherapy

scientific article published on 15 January 2015

Tumor Identification of Less Aggressive or Indolent Lymphoma With Whole-Body 11C-Acetate PET/CT

scientific article published on 01 April 2019

Two M‐components in a single cell lineage in a patient with a dual isotype secretory B‐cell tumour ⬇️

scientific article published on 01 August 1998

[Refractory primary myeloid sarcoma of the breast with MLL-AF9 rearrangement]

scientific article published on 01 January 2016

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