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List of works by John Muscedere

7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial

scientific article published on 17 February 2018

A 2015 Update on Ventilator-Associated Pneumonia: New Insights on Its Prevention, Diagnosis, and Treatment

scientific article published on August 2015

A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards

scientific article published on 15 January 2020

A qualitative study of the variable effects of audit and feedback in the ICU.

scientific article published on 27 April 2015

A randomized trial of glutamine and antioxidants in critically ill patients

scientific article published on April 2013

A ventilator strategy combining low tidal volume ventilation, recruitment maneuvers, and high positive end-expiratory pressure does not increase sedative, opioid, or neuromuscular blocker use in adults with acute respiratory distress syndrome and ma

scientific article

Admission of the very elderly to the intensive care unit: family members' perspectives on clinical decision-making from a multicenter cohort study

scientific article published on 02 February 2015

An environmental scan of quality indicators in critical care

scientific article

Assessing frailty in the intensive care unit: A reliability and validity study

scientific article published on 08 February 2018

Assessing the relationship between near-infrared spectroscopy-derived regional cerebral oxygenation and neurological dysfunction in critically ill adults: a prospective observational multicentre protocol, on behalf of the Canadian Critical Care Tria

scientific article published on 25 June 2019

Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for a systematic review and meta-analysis

article

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol

scientific article published on 11 May 2020

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial

scientific article published on 18 April 2015

Brain Tissue Oxygenation in Patients with Septic Shock: a Feasibility Study

scientific article published on 04 September 2015

Burden of illness in venous thromboembolism in critical care: a multicenter observational study

scientific article published on 01 December 2005

Canadian Guidelines for the use of targeted temperature management (therapeutic hypothermia) after cardiac arrest: A joint statement from The Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critic

scientific article published on 25 September 2015

Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: a randomized placebo controlled pilot trial (CANTREAT study).

scientific article published in July 2014

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia: A Systematic Review and Meta-Analysis

scientific article published on 23 October 2020

Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting

scientific article published on February 14, 2011

Clinically Meaningful Change for Physical Performance: Perspectives of the ICFSR Task Force

scientific article published on 01 January 2020

Coagulase-negative Staphylococcus, catheter-related, bloodstream infections and their association with acute phase markers of inflammation in the intensive care unit: An observational study

scientific article published on January 2012

Complications from recruitment maneuvers in patients with acute lung injury: secondary analysis from the lung open ventilation study

scientific article

Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment

scientific article

Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention

scientific article

Correlates of clinical failure in ventilator-associated pneumonia: insights from a large, randomized trial

scientific article

Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients

scientific article

Data initiatives supporting critical care research and quality improvement in Canada: an environmental scan and narrative review

scientific article published on 22 January 2020

Delirium, Cerebral Perfusion and High Frequency Vital Sign Monitoring in the Critically Ill: The CONFOCAL-2 Feasibility Study

scientific article published on 11 August 2020

Diagnosis of ventilator-associated pneumonia in critically ill adult patients-a systematic review and meta-analysis

scientific article published on 18 April 2020

Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study

scientific article published on 27 June 2019

Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients

scientific article published on 22 October 2015

Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial

scientific article published on 20 December 2014

Enhanced protein-energy provision via the enteral route feeding protocol in critically ill patients: results of a cluster randomized trial

scientific article published in December 2013

Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol

scientific article

Enhancing health-care research: an interdisciplinary collaborative approach.

scientific article published in September 2005

Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia

scientific article published on 7 October 2016

Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia

scientific article

Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

scientific article published on September 2016

Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults

scientific article

Exploring the many facets of research in late-life issues

scientific article published on 09 June 2014

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial

Factors influencing decisions by critical care physicians to withdraw life-sustaining treatments in critically ill adult patients with severe traumatic brain injury

scientific article published on 01 June 2019

Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*.

scientific article published on February 2015

Frailty and Aging: How the Danish Experience Might Inform Canada

scientific article published on 01 April 2019

Frailty and associated outcomes and resource utilization following in-hospital cardiac arrest

scientific article published on 27 November 2019

Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy

scientific article published on 08 October 2019

Frailty measurement and outcomes in interventional studies: protocol for a systematic review of randomised control trials.

scientific article published on 26 December 2017

Giving voice to older adults living with frailty and their family caregivers: engagement of older adults living with frailty in research, health care decision making, and in health policy

scientific article published on 17 June 2016

Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial

scientific article published on 05 May 2014

Guidelines, guidelines, guidelines: what are we to do with all of these North American guidelines?

scientific article

Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial

scientific article

Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial.

scientific article

Highlights of the Canadian Frailty Network (CFN) Highly Qualified Personnel Poster Session

Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma Interrupted Time Series Protocol

scientific article

Implementation of clinical practice guidelines for ventilator-associated pneumonia: a multicenter prospective study

scientific article

Infection prevention and control in the intensive care unit: open versus closed models of care

scientific article published on 27 June 2013

Insights Into a "Negative" ICU Trial Derived From Gene Expression Profiling

scientific article published on 01 December 2019

Integrated knowledge translation strategies in the acute care of older people: a scoping review protocol

scientific article

Is This Intensive Care Unit Patient Frail? Unraveling the Complex Interplay between Frailty and Critical Illness

scientific article published in July 2017

Knowledge translation interventions for critically ill patients: a systematic review*.

scientific article

Longitudinal changes in procalcitonin in a heterogeneous group of critically ill patients

scientific article published in October 2012

Management of Acute Respiratory Distress Syndrome and Refractory Hypoxemia. A Multicenter Observational Study

scientific article published on 14 September 2017

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

scientific article

Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research

scientific article published on 01 January 2020

New-onset atrial fibrillation in critically ill patients

scientific article published on May 2015

Noninvasive ventilation practice patterns for acute respiratory failure in Canadian tertiary care centres: A descriptive analysis

scientific article

Nonleg venous thrombosis in critically ill adults: a nested prospective cohort study

scientific article published on May 2014

Pathogens and antimicrobial susceptibility profiles in critically ill patients with bloodstream infections: a descriptive study

scientific article published on 13 October 2016

Patient preferences for outcomes in critical care trials (OPTICS): preliminary results.

scientific article published on 16 March 2015

Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials

scientific article published on 18 March 2011

Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management

scientific article published on 01 January 2019

Prediction scores do not correlate with clinically adjudicated categories of pulmonary embolism in critically ill patients

scientific article published on 30 September 2013

Prevention of Nosocomial Infections in Critically Ill Patients With Lactoferrin: A Randomized, Double-Blind, Placebo-Controlled Study

scientific article published on 01 September 2018

Prevention of nosocomial infections in critically ill patients with lactoferrin (PREVAIL study): study protocol for a randomized controlled trial

scientific article published on 29 September 2016

Procalcitonin for reduced antibiotic exposure in the critical care setting: a systematic review and an economic evaluation

scientific article

Proceedings of the Canadian Frailty Network Summit: Medication Optimization for Frail Older Canadians, Toronto, Monday April 24, 2017.

scientific article published on 22 December 2017

Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018

scientific article published on 01 January 2019

REducing Deaths due to OXidative Stress (The REDOXS Study): Rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically-ill patients

scientific article published on August 2006

Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia

scientific article

Re-evaluating the Inhibition of Stress Erosions (REVISE): a protocol for pilot randomized controlled trial

scientific article published on November 2016

Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study

scientific article published on 26 August 2015

Relationship Between Near-Infrared Spectroscopy-Derived Cerebral Oxygenation and Delirium in Critically Ill Patients: A Systematic Review

scientific article published on 30 October 2018

Reply to Hassoun et al.

scientific article published on 24 March 2017

Response to Letter to the Editor (Mangioni et al)

scientific article published on 20 March 2019

Risk factors for mortality in patients admitted to intensive care units with pneumonia

scientific article published on 11 July 2016

Robotic technology provides objective and quantifiable metrics of neurocognitive functioning in survivors of critical illness:A feasibility study

scientific article published on 12 September 2018

Screening for Frailty in Canada’s Health Care System: A Time for Action

article

Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKI

scientific article published on 21 March 2019

Serum proteomics as a strategy to identify novel biomarkers of neurologic recovery after cardiac arrest: a feasibility study

scientific article published on 10 May 2016

Stepwise Rostrocaudal Brainstem Anesthesia as a Complication of Local Anesthesia: A Case Report.

scientific article published on 6 July 2017

Stress ulcer prophylaxis in critical illness: a Canadian survey.

scientific article

Subglottic Secretion Drainage and Objective Outcomes: A Systematic Review and Meta-Analysis

scientific article

Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis

scientific article published on August 2011

The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study

scientific article

The Very Elderly Admitted to ICU: A Quality Finish?

scientific article published on 01 July 2015

The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: An important determinant of outcome

scientific article published on 01 December 2011

The authors reply

scientific article published on 01 April 2013

The authors reply

The clinical impact and preventability of ventilator-associated conditions in critically ill patients who are mechanically ventilated

scientific article published in November 2013

The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis.

scientific article

The occurrence and impact of bacterial organisms complicating critical care illness associated with 2009 influenza A(H1N1) infection

scientific article published in July 2013

The relationship between Candida species cultured from the respiratory tract and systemic inflammation in critically ill patients with ventilator-associated pneumonia

scientific article published on 14 December 2010

The relationship between immune status as measured by stimulated ex-vivo tumour necrosis factor alpha levels and the acquisition of nosocomial infections in critically ill mechanically ventilated patients

scientific article published on 16 September 2020

The safety of targeted antibiotic therapy for ventilator-associated pneumonia: a multicenter observational study

scientific article published on 01 March 2008

Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes

scientific article

Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit

scientific article

Toothbrushing for critically ill mechanically ventilated patients: a systematic review and meta-analysis of randomized trials evaluating ventilator-associated pneumonia

scientific article published on February 2013

Validation of diagnostic gene sets to identify critically ill patients with sepsis

article

Ventilator-Associated Pneumonia: Update on Etiology, Prevention, and Management

scientific article published on 01 June 2011

Ventilator-associated pneumonia and mortality: the controversy continues

scientific article published in October 2009

Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: prevalence, incidence, risk factors, and outcomes

scientific article published on 01 March 2008

Ventilator-associated pneumonia: Improving outcomes through guideline implementation

scientific article published on March 2008

Which antibiotic for hospital acquired pneumonia caused by MRSA?

scientific article published on 13 February 2014

Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study

scientific article

Withholding Pantoprazole for Stress Ulcer Prophylaxis in Critically Ill Patients: A Pilot Randomized Clinical Trial and Meta-Analysis

scientific article published on 27 April 2017