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List of works by Mingyan Cao

A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins.

scientific article published on 14 August 2017

A method to directly analyze free-drug-related species in antibody-drug conjugates without sample preparation

scientific article published on 05 April 2019

A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture

scientific article published on 20 September 2018

An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping

scientific article published on 30 July 2019

Cathepsin L Causes Proteolytic Cleavage of CHO Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

scientific article published on 04 November 2018

Characterization and analysis of scFv-IgG bispecific antibody size variants

scientific article published on 20 September 2018

Characterization and quantification of succinimide using peptide mapping under low-pH conditions and hydrophobic interaction chromatography

scientific article published on 29 November 2018

Charge variants characterization and release assay development for co-formulated antibodies as a combination therapy

scientific article published on 20 February 2019

Double-peak elution profile of a monoclonal antibody in cation exchange chromatography is caused by histidine-protonation-based charge variants

scientific article published on 05 November 2015

Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability

scientific article

Qualification of a Quantitative Method for Monitoring Aspartate Isomerization of a Monoclonal Antibody by Focused Peptide Mapping

scientific article published on 18 April 2016

Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis

scientific article published on 14 June 2019

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