List of works - Mohamed Lamkanfi

A new lead to NLRP3 inhibition

scientific article

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

scientific article published on 23 May 2018

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

scientific article published on 20 April 2020

Complementarity and redundancy of IL-22-producing innate lymphoid cells.

scientific article

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

scientific article published on 04 February 2019

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

scientific article published on 11 January 2021

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

scientific article

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

scientific article

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

scientific article published on 16 September 2019

NLRP2 controls age-associated maternal fertility

scientific article

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

scientific article published on 23 September 2019

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture.

scientific article published on 17 April 2018

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

scientific article published on 15 July 2019

The emerging roles of inflammasome-dependent cytokines in cancer development

scientific article published on 17 May 2019

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

scientific article published on 16 March 2015

Therapeutic modulation of inflammasome pathways

scientific article published on 07 August 2020

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

scientific article published on 16 March 2020

List of works by Mohamed Lamkanfi

A new lead to NLRP3 inhibition

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

Complementarity and redundancy of IL-22-producing innate lymphoid cells.

DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

Inflammasomes in neuroinflammatory and neurodegenerative diseases.

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

NLRP2 controls age-associated maternal fertility

Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture.

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax

The emerging roles of inflammasome-dependent cytokines in cancer development

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

Therapeutic modulation of inflammasome pathways

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities