List of works - Niels Frimodt-Møller

"Population structure of drug-susceptible,-resistant and ESBL-producing Escherichia coli from community-acquired urinary tract"

scientific article

A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane

scientific article

An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action.

scientific article published on 16 November 2015

Antibiotic exposure in a low-income country: Screening urine samples for presence of antibiotics and antibiotic resistance in coagulase negative staphylococcal contaminants

scientific article

Antibiotic selection of Escherichia coli sequence type 131 in a mouse intestinal colonization model

scientific article

Attenuation of the bacterial load in blood by pretreatment with granulocyte-colony-stimulating factor protects rats from fatal outcome and brain damage during Streptococcus pneumoniae meningitis

scientific article

Beta-hemolytic streptococcal bacteremia: a review of 241 cases

scientific article

Beta-lactamase producing Escherichia coli isolates in imported and locally produced chicken meat from Ghana

scientific article

Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections.

scientific article

Carriage and serotype distribution of Streptococcus agalactiae in third trimester pregnancy in southern Ghana

scientific article

Cerebral blood flow autoregulation in early experimental S. pneumoniae meningitis

scientific article published on 28 September 2006

Changing epidemiology of pediatric Staphylococcus aureus bacteremia in Denmark from 1971 through 2000.

scientific article published in May 2007

Ciprofloxacin pharmacokinetics/pharmacodynamics (PKPD) against susceptible and low level resistant Escherichia coli in an experimental ascending urinary tract infection model in mice

scientific article published on 26 October 2020

Clinical accuracy of point-of-care urine culture in general practice

scientific article

Commensal streptococci serve as a reservoir for β-lactam resistance genes in Streptococcus pneumoniae.

scientific article published on 6 April 2015

Comment on: withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health

scientific article published on 19 September 2007

Comparative Activity of Ceftriaxone, Ciprofloxacin, and Gentamicin as a Function of Bacterial Growth Rate Probed by Escherichia coli Chromosome Replication in the Mouse Peritonitis Model

scientific article published on 29 January 2019

Comparative Evaluation of Inoculation of Urine Samples with the Copan WASP and BD Kiestra InoqulA Instruments

scientific article published on 25 November 2015

Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples

scientific article

Correlation between pharmacokinetic/pharmacodynamic parameters and efficacy for antibiotics in the treatment of urinary tract infection

scientific article

Danish integrated antimicrobial resistance monitoring and research program

scientific article

Detection of clonal group A Escherichia coli isolates from broiler chickens, broiler chicken meat, community-dwelling humans, and urinary tract infection (UTI) patients and their virulence in a mouse UTI model ⬇️

scientific article published on October 29, 2010

Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

scientific article

Epidemiology of Staphylococcus aureus bacteremia in Denmark from 1957 to 1990.

scientific article published in June 1997

High cerebrospinal fluid (CSF) penetration and potent bactericidal activity in CSF of NZ2114, a novel plectasin variant, during experimental pneumococcal meningitis

scientific article published on 02 February 2009

How predictive is PK/PD for antibacterial agents?

scientific article

Impact of bacteremia on the pathogenesis of experimental pneumococcal meningitis

scientific article

In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging

scientific article

In vivo transfer of the vanA resistance gene from an Enterococcus faecium isolate of animal origin to an E. faecium isolate of human origin in the intestines of human volunteers

scientific article

Influence of antidrug antibodies on plectasin efficacy and pharmacokinetics

scientific article published on 17 August 2009

Influence of the blood bacterial load on the meningeal inflammatory response in Streptococcus pneumoniae meningitis

scientific article published on 27 April 2006

Interplay in the selection of fluoroquinolone resistance and bacterial fitness

scientific article

Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro.

scientific article

Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model

scientific article

Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro

scientific article published on 7 March 2010

Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model

scientific article published on 17 February 2009

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

scientific article published on 9 June 2010

Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents

scientific article published on 30 June 2008

Penicillin resistance and serotype distribution of Streptococcus pneumoniae in Ghanaian children less than six years of age

scientific article

Pharmacokinetics and Pharmacodynamics of Fosfomycin and its Activity against ESBL-, Plasmid-mediated AmpC- and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

scientific article published on 26 March 2018

Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model

scientific article published on 08 September 2009

Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

scientific article published on August 2004

Selection of resistant Streptococcus pneumoniae during penicillin treatment in vitro and in three animal models

scientific article

Selection of unique Escherichia coli clones by random amplified polymorphic DNA (RAPD): Evaluation by whole genome sequencing

scientific article

Structure--activity study of the antibacterial peptide fallaxin

scientific article

Synergy between Mecillinam and Ceftazidime/Avibactam or Avibactam against Multi-Drug-Resistant Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae

scientific article published in 2022

The effect of S. pneumoniae bacteremia on cerebral blood flow autoregulation in rats

scientific article

The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide.

scientific article published on 19 August 2015

The efficacy of pivmecillinam: 3 days or 5 days t.i.d against community acquired uncomplicated lower urinary tract infections - a randomized, double-blinded, placebo-controlled clinical trial study protocol

scientific article

Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases

scientific article published in January 2002

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

scientific article published on 20 January 2016

Virulence of Escherichia coli B2 isolates from meat and animals in a murine model of ascending urinary tract infection (UTI): evidence that UTI is a zoonosis

scientific article

List of works by Niels Frimodt-Møller

"Population structure of drug-susceptible,-resistant and ESBL-producing Escherichia coli from community-acquired urinary tract"

A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane

An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action.

Antibiotic exposure in a low-income country: Screening urine samples for presence of antibiotics and antibiotic resistance in coagulase negative staphylococcal contaminants

Antibiotic selection of Escherichia coli sequence type 131 in a mouse intestinal colonization model

Attenuation of the bacterial load in blood by pretreatment with granulocyte-colony-stimulating factor protects rats from fatal outcome and brain damage during Streptococcus pneumoniae meningitis

Beta-hemolytic streptococcal bacteremia: a review of 241 cases

Beta-lactamase producing Escherichia coli isolates in imported and locally produced chicken meat from Ghana

Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections.

Carriage and serotype distribution of Streptococcus agalactiae in third trimester pregnancy in southern Ghana

Cerebral blood flow autoregulation in early experimental S. pneumoniae meningitis

Changing epidemiology of pediatric Staphylococcus aureus bacteremia in Denmark from 1971 through 2000.

Ciprofloxacin pharmacokinetics/pharmacodynamics (PKPD) against susceptible and low level resistant Escherichia coli in an experimental ascending urinary tract infection model in mice

Clinical accuracy of point-of-care urine culture in general practice

Commensal streptococci serve as a reservoir for β-lactam resistance genes in Streptococcus pneumoniae.

Comment on: withdrawal of growth-promoting antibiotics in Europe and its effects in relation to human health

Comparative Activity of Ceftriaxone, Ciprofloxacin, and Gentamicin as a Function of Bacterial Growth Rate Probed by Escherichia coli Chromosome Replication in the Mouse Peritonitis Model

Comparative Evaluation of Inoculation of Urine Samples with the Copan WASP and BD Kiestra InoqulA Instruments

Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples

Correlation between pharmacokinetic/pharmacodynamic parameters and efficacy for antibiotics in the treatment of urinary tract infection

Danish integrated antimicrobial resistance monitoring and research program

Detection of clonal group A Escherichia coli isolates from broiler chickens, broiler chicken meat, community-dwelling humans, and urinary tract infection (UTI) patients and their virulence in a mouse UTI model ⬇️

Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

Epidemiology of Staphylococcus aureus bacteremia in Denmark from 1957 to 1990.

High cerebrospinal fluid (CSF) penetration and potent bactericidal activity in CSF of NZ2114, a novel plectasin variant, during experimental pneumococcal meningitis

How predictive is PK/PD for antibacterial agents?

Impact of bacteremia on the pathogenesis of experimental pneumococcal meningitis

In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging

In vivo transfer of the vanA resistance gene from an Enterococcus faecium isolate of animal origin to an E. faecium isolate of human origin in the intestines of human volunteers

Influence of antidrug antibodies on plectasin efficacy and pharmacokinetics

Influence of the blood bacterial load on the meningeal inflammatory response in Streptococcus pneumoniae meningitis

Interplay in the selection of fluoroquinolone resistance and bacterial fitness

Intra- and extracellular activities of dicloxacillin against Staphylococcus aureus in vivo and in vitro.

Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model

Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro

Intracellular activity of antibiotics against Staphylococcus aureus in a mouse peritonitis model

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents

Penicillin resistance and serotype distribution of Streptococcus pneumoniae in Ghanaian children less than six years of age

Pharmacokinetics and Pharmacodynamics of Fosfomycin and its Activity against ESBL-, Plasmid-mediated AmpC- and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

Plectasin shows intracellular activity against Staphylococcus aureus in human THP-1 monocytes and in a mouse peritonitis model

Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

Selection of resistant Streptococcus pneumoniae during penicillin treatment in vitro and in three animal models

Selection of unique Escherichia coli clones by random amplified polymorphic DNA (RAPD): Evaluation by whole genome sequencing

Structure--activity study of the antibacterial peptide fallaxin

Synergy between Mecillinam and Ceftazidime/Avibactam or Avibactam against Multi-Drug-Resistant Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae

The effect of S. pneumoniae bacteremia on cerebral blood flow autoregulation in rats

The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide.

The efficacy of pivmecillinam: 3 days or 5 days t.i.d against community acquired uncomplicated lower urinary tract infections - a randomized, double-blinded, placebo-controlled clinical trial study protocol

Treatment and outcome of Staphylococcus aureus bacteremia: a prospective study of 278 cases

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

Virulence of Escherichia coli B2 isolates from meat and animals in a murine model of ascending urinary tract infection (UTI): evidence that UTI is a zoonosis