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List of works by Aytuğ K Kiper

A lower X-gate in TASK channels traps inhibitors within the vestibule

scientific article published on 29 April 2020

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels ⬇️

scientific article published on 01 February 2019

An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities

scientific article published on 3 November 2015

Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening

scientific article published on 17 August 2019

Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.

scientific article

Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.

scientific article

Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site

scientific article published on 01 January 2019

Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?

scientific article published on 17 December 2014

Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.

scientific article published on 27 February 2017

Stress-Kinase Regulation of TASK-1 and TASK-3.

scientific article published on 27 November 2017

Stretch-activated potassium currents in the heart: Focus on TREK-1 and arrhythmias

scientific article

Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine ⬇️

scientific article published on 07 May 2019

TASK Channels Pharmacology: New Challenges in Drug Design

scientific article published on 15 July 2019

TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes.

scientific article

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function

scientific article published on 07 June 2018

The molecular basis for an allosteric inhibition of K-flux gating in K channels

scientific article published on 26 February 2019

The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias

scientific article

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