List of works - Friederike Zunke

ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.

scientific article published on 22 February 2018

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

scientific article published on 8 November 2013

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.

scientific article published on July 2016

Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2.

scientific article published on 21 March 2016

Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation ⬇️

scientific article published on 04 May 2019

Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain

scientific article published on 30 October 2020

LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease

scientific article

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance

scientific journal article

Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease

scientific article

Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2.

scientific article published on 29 July 2015

Modeling neuronopathic storage diseases with patient-derived culture systems

scientific article published on 19 February 2019

Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries ⬇️

scientific article published on June 1, 2012

Reduced KCNQ4-Encoded Voltage-Dependent Potassium Channel Activity Underlies Impaired β-Adrenoceptor–Mediated Relaxation of Renal Arteries in Hypertension ⬇️

scientific article published on February 21, 2012

Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide.

scientific article published on 20 December 2017

Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein

scientific article published on 21 October 2019

Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells

article

The shedding protease ADAM17: Physiology and pathophysiology

scientific article published on 10 July 2017

α-Synuclein in Parkinson's disease: causal or bystander?

scientific article published on 25 June 2019

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

scientific article published on 2 February 2016

List of works by Friederike Zunke