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List of works by Philippe Pourquier

Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer

scientific article published on 4 July 2017

BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients

scientific article

Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase 1: artificial analogues of DNA mimic proteins

scientific article published on 01 June 2019

Early objective response may not be a prognostic factor of survival for patients with metastatic urothelial carcinoma: from a retrospective analysis of a cohort of 113 patients

scientific article

Elongation of oligonucleotide primers forming a triple helix on double-stranded DNA templates by purified DNA polymerases ⬇️

scientific article published on November 14, 2003

From old alkylating agents to new minor groove binders.

scientific article published on 20 August 2013

High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor

scientific article published on 16 June 2020

Induction of Topoisomerase I Cleavage Complexes by the Vinyl Chloride Adduct 1,N 6-Ethenoadenine ⬇️

scientific article published on October 16, 1998

Interaction of Human Nuclear Topoisomerase I with Guanosine Quartet-forming and Guanosine-rich Single-stranded DNA and RNA Oligonucleotides ⬇️

scientific article published on December 26, 2001

Major efficacy of trabectedin in 2 metastatic osteosarcoma patients with wild-type Asp1104 ERCC5 tumor status.

scientific article published on 14 October 2013

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme ⬇️

scientific article published on 01 October 1998

Molecular determinants of response to topoisomerase I inhibitors ⬇️

scientific article published on November 1, 2011

Molecular determinants of response to topoisomerase II inhibitors ⬇️

scientific article published on 01 November 2011

Multiplexed-Based Assessment of DNA Damage Response to Chemotherapies Using Cell Imaging Cytometry

scientific article published on 20 May 2022

Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial.

scientific article

Redox mechanism of levobupivacaine cytostatic effect on human prostate cancer cells.

scientific article published on 31 May 2018

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer.

scientific article published on 17 February 2018

Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA.

scientific article published on 2 April 2018

Structural Basis for Topoisomerase I Inhibition by Nucleoside Analogs ⬇️

scientific article published on May 1, 2003

Targeting the genetic alterations of the PI3K-AKT-mTOR pathway: its potential use in the treatment of bladder cancers

scientific article

The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor

scientific article published on 08 July 2020

The Polyphenolic Ellagitannin Vescalagin Acts As a Preferential Catalytic Inhibitor of the α Isoform of Human DNA Topoisomerase II ⬇️

scientific article published on April 23, 2012

[Genetic and transcriptional evolution alters cancer cell line drug response]

scientific article published on 27 December 2018

[How to manipulate DNA repair to generate neoantigens and ameliorate the efficacy of immunotherapies]

scientific article published on 23 August 2018

[Neural progenitors of the brain migrate into prostate and breast tumors and promote tumour growth and metastasis]

scientific article published on 23 August 2019

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