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List of works by Yasuaki Tamura

A calcium binding protein, S100A4, mediates T cell dependent cytotoxicity as a transformation-associated antigen.

scientific article published on January 2005

A novel nuclear DnaJ protein, DNAJC8, can suppress the formation of spinocerebellar ataxia 3 polyglutamine aggregation in a J-domain independent manner.

scientific article

A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins.

scientific article published on February 2005

Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer

scientific article

Aberrant expression and potency as a cancer immunotherapy target of inhibitor of apoptosis protein family, Livin/ML-IAP in lung cancer.

scientific article published on February 2005

Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth

scientific article

An unusual elevated lesion of the oesophagus

scientific article published on 30 August 2010

Analysis of a Shared Pancreatic Cancer Antigen Recognized by an HLA-A*2601-Restricted Cytotoxic T-Lymphocyte Clone ⬇️

scientific article published on May 1, 2003

Biological heterogeneity of the peptide-binding motif of the 70-kDa heat shock protein by surface plasmon resonance analysis

scientific article

Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding

scientific article

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

scientific article published on 21 April 2016

Cancer-associated oxidoreductase ERO1-α drives the production of tumor-promoting myeloid-derived suppressor cells via oxidative protein folding.

scientific article

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

scientific article

Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma.

scientific article published in June 2009

Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma

scientific article

Combined use of dendritic cells enhances specific antileukemia immunity by leukemia cell-derived heat shock protein 70 in a mouse model with minimal residual leukemia cells

scientific article published on December 2006

Comparison of speedy PCR-ssp method and serological typing of HLA-A24 for Japanese cancer patients ⬇️

scientific article published on January 1, 2011

CpG-A stimulates Hsp72 secretion from plasmacytoid dendritic cells, facilitating cross-presentation

scientific article published on 30 June 2015

Cytotoxic T Lymphocytes Efficiently Recognize Human Colon Cancer Stem-Like Cells ⬇️

scientific article published on April 1, 2011

DNA methyltransferase 1 is essential for initiation of the colon cancers

scientific article

ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells ⬇️

scientific article published on March 12, 2012

ERO1α is a novel endogenous marker of hypoxia in human cancer cell lines.

scientific article

Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells

scientific article

Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population ⬇️

scientific article published on October 2, 2011

Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway

scientific article published on August 2007

Endoplasmic reticulum oxidase 1α is critical for collagen secretion from and membrane type 1-matrix metalloproteinase levels in hepatic stellate cells

scientific article published on 3 August 2017

EpsinR, a target for pyrenocine B, role in endogenous MHC-II-restricted antigen presentation

scientific article

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480

scientific article

Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue: unusually high frequency of down-regulation in breast cancer tissues

scientific article published on 16 March 2012

Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells

scientific article published on 8 October 2009

Expression and function of FERMT genes in colon carcinoma cells

scientific article published on January 1, 2013

Expression of ECRG4 is associated with lower proliferative potential of esophageal cancer cells ⬇️

scientific article published on August 1, 2013

Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells ⬇️

scientific article published on March 18, 2011

Granulocyte-macrophage colony-stimulating factor gene-transduced tumor cells combined with tumor-derived gp96 inhibit tumor growth in mice

scientific article published on May 2003

Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy

scientific article published on 08 October 2009

HLA-restricted specific tumor cytolysis by autologous T-lymphocytes infiltrating metastatic bone malignant fibrous histiocytoma of lymph node

scientific article published on January 2006

HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.

scientific article published on 2 May 2012

HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α

scientific article published on 04 May 2020

Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α

scientific article published on 26 February 2020

Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

scientific article

Heat shock protein 47 confers chemoresistance on pancreatic cancer cells by interacting with calreticulin and IRE1α

scientific article published on 09 June 2021

Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.

scientific article

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells

scientific article published on 15 December 2014

Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells

scientific article

Heat shock proteins and immunity: application of hyperthermia for immunomodulation

scientific article published on December 2009

Heat-Shock Proteins as Endogenous Ligands Building a Bridge Between Innate and Adaptive Immunity ⬇️

scientific article published on August 1, 2012

High expression of ALDH1 and SOX2 diffuse staining pattern of oral squamous cell carcinomas correlates to lymph node metastasis ⬇️

scientific article published on August 16, 2012

Human endoplasmic reticulum oxidoreductin 1-like α regulates immune response of cancer cells via modulation of major histocompatibility complex class I expression and oxidation

scientific article published on 01 November 2012

Human endoplasmic reticulum oxidoreductin 1-α is a novel predictor for poor prognosis of breast cancer

scientific article published on 21 May 2013

Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-α-mediated oxidative folding in murine tumor cells

scientific article published on 26 September 2016

Hypoxia-inducible ERO1α promotes cancer progression through modulation of integrin-β1 modification and signalling in HCT116 colorectal cancer cells

scientific article

Identification of HLA-A24-restricted epitopes with high affinities to Hsp70 using peptide arrays

scientific article published in March 2008

Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells

scientific article published on March 2010

Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients

scientific article published on 24 April 2011

Immunoregulatory role of the protein quality control system

scientific article published in May 2004

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

scientific article published on 16 December 2012

Immunotherapy with dendritic cells pulsed with tumor-derived gp96 against murine lung cancer is effective through immune response of CD8+ cytotoxic T lymphocytes and natural killer cells

scientific article

Improved generation of HLA class I/peptide tetramers

scientific article

Induction of autologous CD4- and CD8-mediated T-cell responses against acute lymphocytic leukemia cell line using apoptotic tumor cell-loaded dendritic cells

scientific article published on February 2006

Inhibition of CD62L+ T-cell response in vitro via a novel sulfo-glycolipid, beta-SQAG9 liposome that binds to CD62L molecule on the cell surface

scientific article published on November 2004

Inhibition of endogenous MHC class II-restricted antigen presentation by tacrolimus (FK506) via FKBP51.

scientific article published on July 2007

Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy

scientific article

Localization and function in endoplasmic reticulum stress tolerance of ERdj3, a new member of Hsp40 family protein

scientific article

Mechanism of putative neo-antigen formation from N-propionyl-4-S-cysteaminylphenol, a tyrosinase substrate, in melanoma models

scientific article published on 21 June 2012

Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles

scientific article published on 21 February 2013

Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release

scientific article published on September 2010

Microenvironmental stresses induce HLA-E/Qa-1 surface expression and thereby reduce CD8(+) T-cell recognition of stressed cells

scientific article published on 29 December 2015

Molecular pathological approaches to human tumor immunology

scientific article published on April 2009

N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model

scientific article published on 2 May 2012

N-propionyl-cysteaminylphenol-magnetite conjugate (NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells

scientific article published on 19 March 2009

Novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4.

scientific article

Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy

scientific article published on 9 February 2016

Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer

scientific article

Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27.

scientific article published on 18 March 2017

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.

scientific article published on 13 July 2016

Polyamine compound deoxyspergualin inhibits heat shock protein-induced activation of immature dendritic cells

scientific article

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity ⬇️

scientific article published on September 19, 2011

Six-transmembrane epithelial antigen of the prostate-1 plays a role for in vivo tumor growth via intercellular communication ⬇️

scientific article published on August 2, 2013

Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal

scientific article published on 13 August 2013

Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome

scientific article published on 14 May 2010

Suppression of alloreactivity and allograft rejection by SP600125, a small molecule inhibitor of c-Jun N-terminal kinase

scientific article published on 01 May 2007

T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles

scientific article published on 15 October 2012

T-cell receptor variable gamma chain gene expression in the interaction between rat gammadelta-type T cells and heat-shock protein 70-like molecule

scientific article

TLR4 and NLRP3 inflammasome activation in monocytes by N-propionyl cysteaminylphenol-maleimide-dextran (NPCMD).

scientific article published on 14 November 2013

Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen-regulated protein 150-peptide complexes

scientific article

The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma

scientific article published on 13 October 2010

Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity ⬇️

scientific article published on February 21, 2011

Tumor-derived heat shock protein 70-pulsed dendritic cells elicit tumor-specific cytotoxic T lymphocytes (CTLs) and tumor immunity

scientific article published on March 2004

Vitamin A and insulin are required for the maintenance of hepatic stellate cell quiescence

scientific article published on 23 January 2016

[Current and future aspects of human tumor immunotherapy]

scientific article published on 01 January 2003

[Heat shock protein inhibitor for molecular targeting therapy]

scientific article published on 01 November 2012

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