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List of works by Thomas Carr

A Phase 1 open-label study to identify a dosing regimen of the pan-AKT inhibitor AZD5363 for evaluation in solid tumors and in PIK3CA-mutated breast and gynecologic cancers.

scientific article published on 24 October 2017

A reliable method for the detection of BRCA1 and BRCA2 mutations in fixed tumour tissue utilising multiplex PCR-based targeted next generation sequencing

scientific article

An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice

scientific article published on 7 December 2017

Circulating Biomarkers and Resistance to Endocrine Therapy in Metastatic Breast Cancers: Correlative Results from AZD9496 Oral SERD Phase I Trial

scientific article published on 06 August 2018

Defining actionable mutations for oncology therapeutic development.

scientific article published on April 2016

EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291.

scientific article published on 9 October 2015

Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia

scientific article published on 01 October 2014

Optimisation of robust singleplex and multiplex droplet digital PCR assays for high confidence mutation detection in circulating tumour DNA

scientific article published on 02 September 2019

RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib

scientific article

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.

scientific article

The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

scientific article

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