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List of works by Brian O. Bachmann

A bifunctional nitrone conjugated secondary metabolite targeting the ribosome

scientific article published on 24 July 2020

A unifying nitrososynthase involved in nitrosugar biosynthesis

scientific article published on November 2008

Adenylation enzyme characterization using gamma -(18)O(4)-ATP pyrophosphate exchange

scientific article

Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism ⬇️

scientific article published on 22 January 2013

Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase

scientific article published on 02 December 2021

Applied evolutionary theories for engineering of secondary metabolic pathways

scientific article

Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis.

scientific article

Bacillus cereus Phosphopentomutase Is an Alkaline Phosphatase Family Member That Exhibits an Altered Entry Point into the Catalytic Cycle

scientific article

Benzodiazepine biosynthesis in Streptomyces refuineus.

scientific article

Bioactive oligosaccharide natural products

scientific article published on August 2014

Biocatalysis in pharmaceutical preparation and alteration

scientific article

Bioretrosynthetic construction of a didanosine biosynthetic pathway

scientific article

Biosynthesis of the Apoptolidins in Nocardiopsis sp. FU 40. ⬇️

scientific article

Biosynthesis: is it time to go retro?

scientific article published in June 2010

Chapter 8. Methods for in silico prediction of microbial polyketide and nonribosomal peptide biosynthetic pathways from DNA sequence data

scientific article

Combined chemical and biosynthetic route to access a new apoptolidin congener

scientific article published on July 2009

Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites

scientific article published on 7 September 2016

Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor

scientific article

Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster

scientific article

Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus.

scientific article published on 24 June 2010

Design and directed evolution of a dideoxy purine nucleoside phosphorylase

scientific article

Distance geometry protocol to generate conformations of natural products to structurally interpret ion mobility-mass spectrometry collision cross sections

scientific article

Fixing the Unfixable: The Art of Optimizing Natural Products for Human Medicine

scientific article published on 26 April 2019

Fluorescent probes of the apoptolidins and their utility in cellular localization studies

scientific article

Identification of ACE pharmacophore in the phosphonopeptide metabolite K-26.

scientific article published on 5 December 2007

Interkingdom Pharmacology of Angiotensin-I Converting Enzyme Inhibitor Phosphonates Produced by Actinomycetes

scientific article

Lactococcus lactis fabH, encoding beta-ketoacyl-acyl carrier protein synthase, can be functionally replaced by the Plasmodium falciparum congener.

scientific article published on 23 April 2010

Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry ⬇️

scientific article

Lipophilic mediated assays for beta-hematin inhibitors

scientific article

Mapping Microbial Response Metabolomes for Induced Natural Product Discovery. ⬇️

scientific article published on 17 June 2015

Metabolic model for diversity-generating biosynthesis

scientific article published on February 2016

Methyltransferase contingencies in the pathway of everninomicin D antibiotics and analogs

scientific article published on 19 July 2020

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

scientific article

Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase.

scientific article

Nitrososynthase-triggered oxidative carbon-carbon bond cleavage in baumycin biosynthesis

scientific article published on 25 July 2013

Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily

scientific article

Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data

scientific article

Reassembly of anthramycin biosynthetic gene cluster by using recombinogenic cassettes

scientific article published on July 2008

Spatiochemically Profiling Microbial Interactions with Membrane Scaffolded Desorption Electrospray Ionization-Ion Mobility-Imaging Mass Spectrometry and Unsupervised Segmentation

scientific article published on 24 October 2019

Structural mass spectrometry: rapid methods for separation and analysis of peptide natural products

scientific article

Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete. ⬇️

scientific article

Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis .

scientific article

Structure of DnmZ, a nitrososynthase in the Streptomyces peucetius anthracycline biosynthetic pathway ⬇️

scientific article

Structuring Microbial Metabolic Responses to Multiplexed Stimuli via Self-Organizing Metabolomics Maps

scientific article

The IsdG-family of haem oxygenases degrades haem to a novel chromophore

scientific article

The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains

scientific article published on 07 December 2018

The calicheamicin gene cluster and its iterative type I enediyne PKS

scientific article

The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots

scientific article

The use of fluorescently-tagged apoptolidins in cellular uptake and response studies

scientific article

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