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List of works by Bruce C Trapnell

A lymphocyte-mediated cause of secondary PAP.

scientific article published in January 2015

A standardized blood test for the routine clinical diagnosis of impaired GM-CSF signaling using flow cytometry

scientific article

Anaerobic metabolism and quorum sensing by Pseudomonas aeruginosa biofilms in chronically infected cystic fibrosis airways: rethinking antibiotic treatment strategies and drug targets.

scientific article published in December 2002

Assessment and management of pulmonary alveolar proteinosis in a reference center

scientific article

Cell Therapy for Lung Diseases. Report from an NIH–NHLBI Workshop, November 13–14, 2012 ⬇️

scientific article published on August 1, 2013

Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan

scientific article

Complete Tracheal Ring Deformity. A Translational Genomics Approach to Pathogenesis

scientific article published on 01 November 2019

Diffuse Lung Disease in Biopsied Children 2 to 18 Years of Age. Application of the chILD Classification Scheme

scientific article

Diffuse lung disease in young children: application of a novel classification scheme

scientific article

Does Granulocyte-Macrophage Colony-Stimulating Factor Coordinate a Hepatopulmonary Axis of Lipid Metabolism?

scientific article

Early changes in clinical, functional, and laboratory biomarkers in workers at risk of indium lung disease

journal article published in 2014

Efficacy and safety of sirolimus in lymphangioleiomyomatosis

scientific article

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.

scientific article published on 27 October 2008

Fosfomycin/Tobramycin for Inhalation in Patients with Cystic Fibrosis with Pseudomonas Airway Infection ⬇️

scientific article published on November 17, 2011

Genetic disorders influencing lung formation and function at birth

scientific article published in October 2004

Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense

scientific article

Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice

scientific article

Granulocyte-macrophage colony-stimulating factor autoantibodies: a marker of aggressive Crohn's disease

scientific article published on July 2013

Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice.

scientific article published on October 2008

Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects

scientific article published on March 2009

Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy

scientific article

High avidity cytokine autoantibodies in health and disease: pathogenesis and mechanisms

scientific article published on 22 April 2010

Human GM-CSF autoantibodies and reproduction of pulmonary alveolar proteinosis

scientific article published in December 2009

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

scientific article

Increased Prevalence of Luminal Narrowing and Stricturing Identified by Enterography in Pediatric Crohn’s Disease Patients With Elevated Granulocyte–Macrophage Colony Stimulating Factor Autoantibodies ⬇️

scientific article published on September 1, 2013

Indium Lung Disease ⬇️

scientific article published on December 29, 2011

Inhaled granulocyte/macrophage-colony stimulating factor as therapy for pulmonary alveolar proteinosis

scientific article

Innate Dysfunction Promotes Linear Growth Failure in Pediatric Crohnʼs Disease and Growth Hormone Resistance in Murine Ileitis§ ⬇️

scientific article published on February 18, 2011

Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages

scientific article

Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury

scientific article

Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review

scientific article published on May 2007

Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates

scientific article

Perspectives for improving the evaluation and access of therapies for rare lung diseases in Europe

scientific article published on 11 March 2012

Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results

scientific article

Physical properties, lung deposition modeling, and bioactivity of recombinant GM-CSF aerosolised with a highly efficient nebulizer.

scientific article

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

scientific article published on March 2017

Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages

scientific article published on 30 September 2009

Pulmonary macrophage transplantation therapy

scientific article

Recombinant Adeno-Associated Virus Vector Genomes Take the Form of Long-Lived, Transcriptionally Competent Episomes in Human Muscle

scientific article published on 09 December 2015

Respirable indium exposures, plasma indium, and respiratory health among indium-tin oxide (ITO) workers

journal article published in 2016

Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial

scientific article

Serum vascular endothelial growth factor-D prospectively distinguishes lymphangioleiomyomatosis from other diseases

scientific article

Standardized serum GM-CSF autoantibody testing for the routine clinical diagnosis of autoimmune pulmonary alveolar proteinosis.

scientific article

The Alveolar Lipidome in Pulmonary Alveolar Proteinosis. A New Target for Therapeutic Development?

scientific article published on 01 October 2019

The molecular basis of pulmonary alveolar proteinosis

scientific article

The parallel lives of alpha1-antitrypsin deficiency and pulmonary alveolar proteinosis

scientific article published on 30 September 2013

Therapy options in pulmonary alveolar proteinosis.

scientific article published on 20 July 2010

Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis

scientific article published on January 2014

Whole lung lavage therapy for pulmonary alveolar proteinosis: a global survey of current practices and procedures.

scientific article published on 31 August 2016

alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary note.

scientific article published on October 2008

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