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List of works by Rajashree A Deshpande

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling

scientific article published on 3 March 2014

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

scientific article published on April 2016

Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.

scientific article published on 22 March 2013

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection

scientific article published on 15 May 2014

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

scientific article published on 08 January 2020

Genetic separation of Sae2 nuclease activity from Mre11 nuclease functions in budding yeast

scientific article published on 2 October 2017

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

scientific article published on November 2016

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

scientific article published in December 2016

Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts.

scientific article

Purification and Biophysical Characterization of the Mre11-Rad50-Nbs1 Complex

scientific article published on 01 January 2019

Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites.

scientific article published on 21 March 2017

Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair

scientific article published on 29 August 2017

The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes

scientific article

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