Search filters

List of works by Reinhold Tacke

(R)-sila-venlafaxine: a selective noradrenaline reuptake inhibitor for the treatment of emesis

scientific article

A zwitterionic spirocyclic pentacoordinate silicon compound synthesized in water by Si--O and Si--C bond cleavage.

scientific article published in August 2005

Action of (R)-sila-venlafaxine and reboxetine to antagonize cisplatin-induced acute and delayed emesis in the ferret.

scientific article published on 15 July 2008

Activation of sulfur dioxide by bis[N,N'-diisopropylbenzamidinato(-)]silicon(II): synthesis of neutral six-coordinate silicon(IV) complexes with chelating O,O'-Sulfito or O,O'-dithionito ligands

scientific article published on 21 August 2014

Asymmetric Synthesis of the Nonproteinogenic Silicon-Containing α-Amino Acids (<i>R</i>)- and (<i>S</i>)-α-[(Trimethylsilyl)methyl]alanine§Dedicated to Professor Johann Weis on the occasion of his 65th birthday.

scientific article published in 2009

Behavior of tri(n-butyl)ammonium bis[citrato(3-)-O1,O3,O6]silicate in aqueous solution: analysis of a sol-gel process by small-angle neutron scattering

scientific article published on 01 April 2005

Bioaktive Siliciumverbindungen

Bis(amidinato)- and bis(guanidinato)silylenes and silylenes with one sterically demanding amidinato or guanidinato ligand: synthesis and reactivity

scientific article published on 25 September 2017

Bis[N,N'-diisopropylbenzamidinato(-)]silicon(II): a silicon(II) compound with both a bidentate and a monodentate amidinato ligand

scientific article published on 31 May 2012

Bis[N,N′-diisopropylbenzamidinato(−)]silicon(II): Lewis Acid/Base Reactions with Triorganylboranes

scientific article published on 11 August 2014

Can silicon make an excellent drug even better? An in vitro and in vivo head-to-head comparison between loperamide and its silicon analogue sila-loperamide

scientific article

Cationic Five-Coordinate Bis(guanidinato)silicon(IV) Complexes with SiN4 El Skeletons (El=S, Se): "Heterolytic Activation" of S-S and Se-Se Bonds

scientific article published on 17 March 2016

Darstellung und Eigenschaften der Enantiomere des selektiven Antimuscarinikums 1-Cyclohexyl-1-phenyl-4-piperidino-1-butanol (Hexahydro-Difenidol)

Dianionic complexes with hexacoordinate silicon(IV) or germanium(IV) and three bidentate ligands of the hydroximato(2-) type: syntheses and structural characterization in the solid state

scientific article

Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation

scientific article published on 20 July 2012

Disila-galaxolide and derivatives: synthesis and olfactory characterization of silicon-containing derivatives of the musk odorant galaxolide

scientific article published on 10 July 2013

Disila-okoumal: a silicon analogue of the ambergris odorant okoumal

scientific article published on 01 August 2007

Electron densities of bexarotene and disila-bexarotene from invariom application: a comparative study.

scientific article published in April 2013

Five-coordinate silicon(II) compounds with Si-M bonds (M = Cr, Mo, W, Fe): Bis[N,N'-diisopropylbenzamidinato(-)]silicon(II) as a ligand in transition-metal complexes

scientific article published on 24 September 2013

High-affinity, selective σ ligands of the 1,2,3,4-tetrahydro-1,4'-silaspiro[naphthalene-1,4'-piperidine] type: syntheses, structures, and pharmacological properties

scientific article published on 11 November 2011

In vitro metabolism of haloperidol and sila-haloperidol: new metabolic pathways resulting from carbon/silicon exchange

scientific article published in January 2010

Invariom based electron density studies on the C/Si analogues haloperidol/sila-haloperidol and venlafaxine/sila-venlafaxine.

scientific article published on 29 July 2015

Iron(II), Cobalt(II), Nickel(II), and Zinc(II) Silylene Complexes: Reaction of the Silylene [iPrNC(NiPr2 )NiPr]2 Si with FeBr2 , CoBr2 , NiBr2 ⋅MeOCH2 CH2 OMe, ZnCl2 , and ZnBr2.

scientific article

Isolation and Characterization of Crystalline, Neutral Diborane(4) Radicals

scientific article published on 21 June 2018

Lower homologues of okoumal and disila-okoumal: synthesis and olfactory characterization of novel ambergris odorants

scientific article published on 01 February 2010

Models for the active site in [FeFe] hydrogenase with iron-bound ligands derived from bis-, tris-, and tetrakis(mercaptomethyl)silanes

scientific article published on November 2010

Moleku¨lstruktur der Akarizide Chlortrineophylstannan, Chlortris[(dimethylphenylsilyl)methyl]stannan und Trineophyl(1, 2, 4-triazol-1-yl)stannan-hemihydrat sowie des 2, 5-Dimethyl-2, 5-diphenylhexans (Bineophyl)

N+/Si Replacement as a Tool for Probing the Pharmacophore of Allosteric Modulators of Muscarinic M2Receptors: Synthesis, Allosteric Potency, and Positive Cooperativity of Silicon-Based W84 Derivatives

Neutral Pentacoordinate Halogeno- and Pseudohalogenosilicon(IV) Complexes with a Tridentate Dianionic O,N,O or N,N,O Ligand: Synthesis and Structural Characterization in the Solid State and in Solution

scientific article published on 23 May 2012

Neutral Six-Coordinate and Cationic Five-Coordinate Silicon(IV) Complexes with Two Bidentate Monoanionic N,S-Pyridine-2-thiolato(−) Ligands

scientific article published on 6 September 2013

Neutral hexa- and pentacoordinate silicon(IV) complexes with SiO(6) and SiO(4)N skeletons

scientific article published on 22 May 2007

Neutral penta- and hexacoordinate silicon(IV) complexes containing two bidentate ligands derived from the alpha-amino acids (S)-alanine, (S)-phenylalanine, and (S)-tert-leucine

scientific article published in June 2010

Neutral pentacoordinate halogeno- and pseudohalogenosilicon(IV) complexes with an SiSONCX skeleton (X=F, Cl, Br, I, N, C): synthesis and structural characterization in the solid state and in solution

scientific article published in June 2010

Neutral pentacoordinate silicon(IV) complexes with silicon-chalcogen (S, Se, Te) bonds

scientific article published on 01 July 2009

Neutral six-coordinate bis(dithiocarbamato)silicon(iv) complexes with an SiCl2S4 skeleton

scientific article published on 7 October 2016

Not unhydrolyzed at pH 8

scientific article published on 01 May 2006

Novel Silicon-Containing Analogues of the Retinoid Agonist Bexarotene: Syntheses and Biological Effects on Human Pluripotent Stem Cells

scientific article published on 01 July 2011

Novel neutral hexacoordinate benzamidinatosilicon(iv) complexes with SiN3OF2, SiN3OCl2, SiN3OBr2, SiN5O and SiN3O3 skeletons ⬇️

scientific article published on August 30, 2011

Novel neutral hexacoordinate silicon(iv) complexes with two bidentate monoanionic benzamidinato ligands ⬇️

scientific article published on 01 September 2010

Novel silicon-based patchouli odorants of the trialkyl(1-hydroxy-1-methylethyl)silane type: design, synthesis, and olfactory properties

scientific article published in July 2010

Novel transition-metal (M=Cr, Mo, W, Fe) carbonyl complexes with bis(guanidinato)silicon(II) ligands

scientific article published on 09 July 2014

Odorant design based on the carbon/silicon switch strategy

scientific article published in June 2008

Optically active zwitterionic lambda(5)Si,lambda(5)Si'-disilicates: syntheses, crystal structures, and behavior in aqueous solution

scientific article

Pentacoordination of Silicon by Four Covalent Si-S Bonds and One Covalent Si-C Bond

scientific article published in June 2001

Pentacoordination of Silicon by Four Covalent Si-S Bonds and One Covalent Si-C Bond This work was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie

scientific article published on 01 June 2001

Pentacoordination of silicon by five different ligand atoms: neutral silicon(IV) complexes with SiClSONC and SiISONC skeletons

scientific article published on 01 January 2007

Prediction of Perception: Probing the hOR17-4 Olfactory Receptor Model with Silicon Analogues of Bourgeonal and Lilial

scientific article published on 01 January 2007

Reactions of the donor-stabilized silylene bis[N,N'-diisopropyl-benzamidinato(-)]silicon(II) with Brønsted acids.

scientific article

Reactivity of the Donor-Stabilized Silylenes [iPrNC(Ph)NiPr]2 Si and [iPrNC(NiPr2 )NiPr]2 Si: Activation of CO2 and CS2.

scientific article published in October 2015

Si- and C-Functional Organosilicon Building Blocks for Synthesis Based on 4-Silacyclohexan-1-ones Containing the Silicon Protecting Groups MOP (4-Methoxyphenyl), DMOP (2,6-Dimethoxyphenyl), or TMOP (2,4,6-Trimethoxyphenyl)

scientific article published on 18 May 2015

Sila-biperiden undendo-Sila-biperiden: Synthesen, Kristallstrukturen und antimuscarinische Eigenschaften

Sila-haloperidol, a silicon analogue of the dopamine (D2) receptor antagonist haloperidol: synthesis, pharmacological properties, and metabolic fate

scientific article published in January 2008

Sila-substitution of alkyl nitrates: synthesis, structural characterization, and sensitivity studies of highly explosive (nitratomethyl)-, bis(nitratomethyl)-, and tris(nitratomethyl)silanes and their corresponding carbon analogues.

scientific article published in June 2010

Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology

scientific article

Silicon analogues of the nonpeptidic GnRH antagonist AG-045572: syntheses, crystal structure analyses, and pharmacological characterization

scientific article published on 27 September 2011

Silicon analogues of the retinoid agonists TTNPB and 3-methyl-TTNPB, disila-TTNPB and disila-3-methyl-TTNPB: chemistry and biology

scientific article published on September 2007

Silicon chemistry as a novel source of chemical diversity in drug design.

scientific article

Silicon α-Effect: A Systematic Experimental and Computational Study of the Hydrolysis of Cα- and Cγ-Functionalized Alkoxytriorganylsilanes of the Formula Type ROSiMe2(CH2)nX (R = Me, Et; n = 1, 3; X = Functional Group)

scientific article published on 20 May 2014

Silylene-Induced Reduction of [Mn2(CO)10]: Formation of a Five-Coordinate Silicon(IV) Complex with an O-Bound [(OC)4Mn=Mn(CO)4]2-Ligand

scientific article published on 23 December 2016

Spirocyclic zwitterionic lambda5Si-silicates with two bidentate ligands derived from alpha-amino acids or alpha-hydroxycarboxylic acids: synthesis, structure, and stereodynamics

scientific article published in November 2004

Stable Five‐Coordinate Silicon(IV) Complexes with SiN4X Skeletons (X=S, Se, Te) and SiX Double Bonds ⬇️

scientific article published on November 22, 2012

Stable Four-Coordinate Guanidinatosilicon(IV) Complexes with SiN3El Skeletons (El = S, Se, Te) and Si=El Double Bonds

scientific article published on 18 August 2015

Stereoselective microbial reduction of racemic acetyl(t-butyl)methylphenylsilane by Trigonopsis variabilis (DSM 70714) and Cornebacterium dioxydans (ATCC 2176)

Synthesis and Pharmacological Properties of Silicon-Containing GPR81 and GPR109A Agonists.

scientific article published on 13 October 2015

Synthesis and olfactory characterization of silicon-containing derivatives of the acyclic lily-of-the-valley odorant 5,7,7-trimethyl-4-methylideneoctanal

scientific article published on 01 November 2014

Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

scientific article published in November 2009

Synthesis and structural characterisation of neutral pentacoordinate silicon(iv) complexes with a tridentate dianionic N,N,S chelate ligand

scientific article published in 2012

Synthesis and structural characterization of neutral hexacoordinate silicon(IV) complexes with SiO2N4 skeletons

scientific article published on 01 April 2009

Synthesis and structural characterization of neutral higher-coordinate silicon(IV) complexes with tridentate dianionic chelate ligands

scientific article published in December 2005

Synthesis and structural characterization of novel neutral hexacoordinate silicon(IV) complexes with SiO2N4 skeletons containing cyanato-N or thiocyanato-N ligands

scientific article published on 01 April 2005

Synthesis, Crystal Structure Analysis, and Pharmacological Characterization of Disila-bexarotene, a Disila-Analogue of the RXR-Selective Retinoid Agonist Bexarotene

scholarly article by Jürgen O. Daiss et al published June 2005 in Organometallics

Synthesis, structure and reactivity of a donor-stabilised silylene with a bulky bidentate benzamidinato ligand

scientific article published on 01 September 2015

The donor-stabilized silylene bis[N,N'-diisopropylbenzamidinato(-)]silicon(II): synthesis, electronic structure, and reactivity.

scientific article published on 5 June 2014

The hexacoordinate silicate dianions mer-tris[glycolato(2-)-O(1),O(2)]silicate and fac-tris[benzilato(2-)-O(1),O(2)]silicate: syntheses and structural characterization

scientific article

The sila-explosives Si(CH2N3)4 and Si(CH2ONO2)4: silicon analogues of the common explosives pentaerythrityl tetraazide, C(CH2N3)4, and Pentaerythritol Tetranitrate, C(CH2ONO2)4

scientific article published on 04 May 2007

The synthesis and the crystal and molecular structure of the fungicide bis(4-fluorophenyl)-methyl(1H-1,2,4-triazol-1-yl-methyl)silane (flusilazole, DPX H 6573)

Tripodal Binding Units for Self-Assembled Monolayers on Gold: A Comparison of Thiol and Thioether Headgroups

scientific article

Unusual silicon coordination polyhedra: non-VSEPR structures of zwitterionic lambda5-Si silicon(IV) complexes with an SiS2N2C or SiS2O2C skeleton

scientific article published on 01 January 2007

Zur absoluten Konfiguration der Enantiomere der Antimuskarinika Procyclidin und Tricyclamoliodid: Röntgen-strukturanalyse von (R)-1-[3-Cyclohexyl-3-hydroxy-3-phenyl-propyl]-1-methylpyrrolidiniumiodid

Zwitterionic and anionic multinuclear pentacoordinate silicon(IV) complexes with bridging (R,R)-tartrato(4-) ligands and SiO5 skeletons: synthesis and reactivity in aqueous solution

scientific article published on 23 January 2012

Paulina is supported by:

About Paulina

Help