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List of works by Ysabella Z A Van Sebille

A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options.

scientific article published on 31 March 2016

Cytokine-mediated blood brain barrier disruption as a conduit for cancer/chemotherapy-associated neurotoxicity and cognitive dysfunction

scientific article

Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer.

scientific article published on 16 September 2017

Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats

scientific article

Editorial Comment

ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: Chloride secretion as a mechanistic hypothesis

scientific article published on 06 June 2015

Gastrointestinal toxicities of first and second-generation small molecule human epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer.

scientific article

Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis

scientific article published on 29 March 2019

Highlight article: Use of zebrafish to model chemotherapy and targeted therapy gastrointestinal toxicity

scientific article published on 11 June 2019

Irinotecan-Induced Gastrointestinal Dysfunction and Pain Are Mediated by Common TLR4-Dependent Mechanisms

scientific article

Management of Mucositis During Chemotherapy: From Pathophysiology to Pragmatic Therapeutics

scientific article

Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report.

scientific article published on 23 December 2016

Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action

scientific article published on 26 June 2020

Prophylactic probiotics for cancer therapy-induced diarrhoea: a meta-analysis.

scientific article

Routine assessment of the gut microbiome to promote preclinical research reproducibility and transparency

scientific article published on 9 January 2017

Selective MMP Inhibition, Using AZD3342, to Reduce Gastrointestinal Toxicity and Enhance Chemoefficacy in a Rat Model

article

Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines

scientific article published on 08 July 2019

TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea.

scientific article published on 22 August 2016

Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer.

scientific article published on 6 October 2015

Toll-like receptor 4 signaling: a common biological mechanism of regimen-related toxicities: an emerging hypothesis for neuropathy and gastrointestinal toxicity

scientific article

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