Search filters

List of works by Arun K Sharma

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

scientific article published on 23 October 2018

Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts

scientific article

Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile.

scientific article

Cationic amphiphilic bolaamphiphile-based delivery of antisense oligonucleotides provides a potentially microbiome sparing treatment for C. difficile.

scientific article published on 19 April 2018

Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity

scientific article published on 21 July 2016

Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells.

scientific article published on 4 November 2017

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents.

scientific article published on 9 January 2016

Design, synthesis and evaluation of Ospemifene analogs as anti-breast cancer agents.

scientific article published on 22 August 2014

Design, synthesis, and anti-breast cancer evaluation of new triarylethylene analogs bearing short alkyl- and polar amino-/amido-ethyl chains

scientific article published on 05 March 2016

Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.

scientific article published on 21 April 2017

Development and Therapeutic Potential of Selenazo Compounds

scientific article published on 05 November 2019

Development of Isoselenocyanate Compounds' Syntheses and Biological Applications

scientific article published on 22 January 2019

Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways

scientific article

Identification and Quantification of DNA Adducts in the Oral Tissues of Mice Treated with the Environmental Carcinogen Dibenzo[a,l]pyrene by HPLC-MS/MS ⬇️

scientific article published on July 19, 2011

Identification and quantification of six-ring C₂₆H₁₆ cata-condensed polycyclic aromatic hydrocarbons in a complex mixture of polycyclic aromatic hydrocarbons from coal tar.

scientific article

Identification of a Novel Quinoxaline-Isoselenourea Targeting the STAT3 Pathway as a Potential Melanoma Therapeutic ⬇️

scientific article published on 26 January 2019

Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice.

scientific article published on 06 June 2013

Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors

scientific article published on 11 February 2014

In vitro growth inhibition of human cancer cells by novel honokiol analogs ⬇️

scientific article published on April 3, 2012

Interaction between APC and Fen1 during breast carcinogenesis

scientific article published on 7 April 2016

Leishmanicidal Activity of Isoselenocyanate Derivatives

scientific article published on 29 January 2019

Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: an environmental pollutant and a tobacco smoke constituent.

scientific article published on 22 April 2013

Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1.

scientific article

Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer

scientific article published in September 2017

Novel selenadiazole derivatives as selective antitumor and radical scavenging agents

scientific article published on 27 July 2018

Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines

scientific article published on 18 February 2016

Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: Thiol reactivity and its implications ⬇️

scientific article published on September 13, 2012

Phenylbutyl isoselenocyanate induces reactive oxygen species to inhibit androgen receptor and to initiate p53-mediated apoptosis in LNCaP prostate cancer cells.

scientific article

Post SELECT: Selenium on Trial ⬇️

scientific article published on February 1, 2013

Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents ⬇️

scientific article (publication date: 15 December 2011)

Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells

scientific article (publication date: 2013)

Selenium Compounds, Apoptosis and Other Types of Cell Death: An Overview for Cancer Therapy ⬇️

scientific article published on 02 August 2012

Simultaneous detection of deoxyadenosine and deoxyguanosine adducts in the tongue and other oral tissues of mice treated with Dibenzo[a,l]pyrene.

scientific article

Sphingo-guanidines and their use as inhibitors of sphingosine kinase (WO2010078247) ⬇️

scientific article published on 04 April 2011

Suppression of Cytokine-Mediated Complement Factor Gene Expression through Selective Activation of the Ah Receptor with 3′,4′-Dimethoxy-α-naphthoflavone ⬇️

scientific article published on December 2, 2010

Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer.

scientific article published on 23 July 2018

Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway ⬇️

scientific article published on August 26, 2011

Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities.

scientific article

The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer

scientific article

The Chemopreventive effect of Withaferin A on spontaneous and Inflammation-associated colon carcinogenesis models

scientific article published on 01 December 2018

Paulina is supported by:

About Paulina

Help