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List of works by Akihiko Shimomura

A case of heavily pretreated metastatic cardiac angiosarcoma treated successfully using eribulin

scientific article published on 23 November 2017

A phase I/II trial of olaparib tablet in combination with eribulin in Japanese patients with advanced or metastatic triple-negative breast cancer previously treated with anthracyclines and taxanes

scientific article published on 28 January 2019

Absent immunoglobulins in HIV-related Burkitt lymphoma/leukaemia

scientific article published on 5 October 2007

Allred score is a promising predictor of prognosis and medroxyprogesterone acetate efficacy in patients with endometrial cancer.

scientific article published on 24 May 2017

Association between duodenal contents reflux and squamous cell carcinoma--establishment of an esophageal cancer cell line derived from the metastatic tumor in a rat reflux model.

scientific article published on January 2007

BRAF V600E mutation is a potential therapeutic target for a small subset of synovial sarcoma

scientific article published on 01 April 2020

BRCA1 promoter methylation in breast cancer patients is associated with response to olaparib/eribulin combination therapy

scientific article published on 20 April 2020

Bone marrow examination in patients with Ewing sarcoma/peripheral primitive neuroectodermal tumor without metastasis based on 18F-fluorodeoxyglucose positron emission tomography/computed tomography

scientific article published on 18 May 2019

Brain metastasis-related microRNAs in patients with advanced breast cancer

scientific article published on 11 October 2019

Cardiotoxicity of adjuvant chemotherapy with trastuzumab: a Japanese claim-based data analysis

scientific article published in 2022

Clinical benefit of treatment after trastuzumab emtansine for HER2-positive metastatic breast cancer: a real-world multi-centre cohort study in Japan (WJOG12519B)

scientific article published on 02 January 2021

Comparison of the efficacy of trastuzumab emtansine between patients with metastatic human epidermal growth factor receptor 2-positive breast cancers previously treated with combination trastuzumab and pertuzumab and with trastuzumab only in Japanes

scientific article published on 08 February 2019

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan

scientific article

Dose exploration results from Phase 1 study of cemiplimab, a human monoclonal programmed death (PD)-1 antibody, in Japanese patients with advanced malignancies

scientific article published on 04 November 2020

Durable complete response in HER2-positive breast cancer: a multicenter retrospective analysis.

scientific article published on 11 September 2017

Efficacy and Safety of Pazopanib for Recurrent or Metastatic Solitary Fibrous Tumor.

scientific article published on 3 April 2018

Efficacy and safety of eribulin in patients with locally advanced or metastatic breast cancer not meeting trial eligibility criteria: a retrospective study

scientific article published on 4 December 2017

Efficacy of capecitabine in patients with locally advanced or metastatic breast cancer with or without prior treatment with fluoropyrimidine: a retrospective study

scientific article published on 05 June 2018

Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study

article

Feasibility of dose-dense paclitaxel/carboplatin therapy in elderly patients with ovarian, fallopian tube, or peritoneal cancer.

scientific article published on 13 August 2016

Feasibility of olanzapine, multi acting receptor targeted antipsychotic agent, for the prevention of emesis caused by continuous cisplatin- or ifosfamide-based chemotherapy

scientific article

First-in-Human Phase I Study of an Oral HSP90 Inhibitor, TAS-116, in Patients with Advanced Solid Tumors

scientific article published on 24 January 2019

First-in-human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

scientific article published on 01 February 2020

Gene Alterations in Triple-Negative Breast Cancer Patients in a Phase I/II Study of Eribulin and Olaparib Combination Therapy

scientific article published on 02 August 2019

Gene aberration profile of tumors of adolescent and young adult females.

scientific article published on 29 December 2017

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

scientific article published on 08 July 2019

HER3 protein expression as a risk factor for post-operative recurrence in patients with early-stage adenocarcinoma and adenosquamous carcinoma of the cervix

scientific article published on 23 July 2020

High-throughput functional evaluation of BRCA2 variants of unknown significance

scientific article published on 22 May 2020

Ifosfamide and Etoposide Chemotherapy in the Treatment of Recurrent/Refractory Rhabdomyosarcoma in Adults

scientific article

Improved survival among patients enrolled in oncology phase 1 trials in recent decades

scientific article published on 19 November 2019

Induction of gastric GIST in rat and establishment of GIST cell line

scientific article

Infection risk with PI3K-AKT-mTOR pathway inhibitors and immune checkpoint inhibitors in patients with advanced solid tumours in phase I clinical trials

scientific article published on 01 April 2020

LC-MS bioanalysis of Trastuzumab and released emtansine using nano-surface and molecular-orientation limited (nSMOL) proteolysis and liquid-liquid partition in plasma of Trastuzumab emtansine-treated breast cancer patients.

scientific article published on 19 June 2017

Long Non-coding NR2F1-AS1 is Associated with Tumor Recurrence in Estrogen Receptor-positive breast cancers

scientific article published on 11 May 2020

Long-term survival analysis of addition of carboplatin to neoadjuvant chemotherapy in HER2-negative breast cancer

scientific article published on 05 March 2020

Neoadjuvant chemotherapy promotes the expression of HER3 in patients with ovarian cancer

scientific article published on 07 October 2020

Novel combination of serum microRNA for detecting breast cancer in the early stage.

scientific article published on 7 January 2016

PIK3CA mutation profiling in patients with breast cancer, using a highly sensitive detection system

scientific article published on 28 July 2018

Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese.

scientific article published on 26 April 2017

Pathologic complete response after neoadjuvant chemotherapy in HER2-overexpressing breast cancer according to hormonal receptor status.

scientific article published on 16 April 2014

Peripheral neuropathy from paclitaxel: risk prediction by serum microRNAs

scientific article published on 14 January 2020

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

scientific article published on 16 June 2016

Phase I study of taselisib in Japanese patients with advanced solid tumors or hormone receptor-positive advanced breast cancer.

scientific article

Phase I study of the indoleamine 2,3-dioxygenase 1 inhibitor navoximod (GDC-0919) as monotherapy and in combination with the PD-L1 inhibitor atezolizumab in Japanese patients with advanced solid tumours

scientific article published on 24 May 2019

Pitfalls in the detection of t(11;22) translocation by fluorescence in situ hybridization and RT-PCR: a single-blinded study

scientific article published on 01 June 2006

Prognostic impact of presumed breast or ovarian cancer among patients with unfavorable-subset cancer of unknown primary site

scientific article published on 13 February 2018

Prolonged Hypocalcemia Following a Single Dose of Denosumab for Diffuse Bone Metastasis of Gastric Cancer after Total Gastrectomy

scientific article published on 25 September 2017

Radiation-induced esophagitis exacerbated by everolimus

scientific article published on May 2013

Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N·SAS-BC 01 trial and CUBC trial)

scientific article published on 01 December 2020

Response to Dabrafenib and Trametinib of a Patient with Metaplastic Breast Carcinoma Harboring a BRAF V600E Mutation

scientific article published on 06 March 2020

Safety, pharmacokinetics, and antitumour activity of trastuzumab deruxtecan (DS-8201), a HER2-targeting antibody-drug conjugate, in patients with advanced breast and gastric or gastro-oesophageal tumours: a phase 1 dose-escalation study

scientific article published on 13 October 2017

Serum miRNA-based Prediction of Axillary Lymph Node Metastasis in Breast Cancer

scientific article published on 27 November 2018

Serum microRNA-based prediction of responsiveness to eribulin in metastatic breast cancer

scientific article published on 04 September 2019

Suggestions Regarding the GEICAM/2003-11_CIBOMA/2004-01 Trial: Future Treatment Options for Early Triple-Negative Breast Cancer

scientific article published on 30 April 2020

Survival outcomes in patients with human epidermal growth factor receptor 2 positive metastatic breast cancer administered a therapy following trastuzumab emtansine treatment

scientific article published on 01 September 2020

Symptom management: the utility of regional cooling for hand-foot syndrome induced by pegylated liposomal doxorubicin in ovarian cancer.

scientific article

TERT promoter hotspot mutations in breast cancer.

scientific article published on 8 December 2017

Taxane-induced sensory peripheral neuropathy is associated with an SCN9A single nucleotide polymorphism in Japanese patients

scientific article published on 16 April 2020

The Incidence of Nonmalignant Diseases among Patients with Suspected Carcinoma of Unknown Primary Site

scientific article published on 01 February 2019

The Prognostic Impact of the Pathological Response to Neoadjuvant Dose-Dense Therapy for Ovarian Carcinoma

scientific article published on 17 October 2017

The Use of PET/CT and Bone Marrow Aspiration/Biopsy in Initial Staging Evaluation of Adolescent and Adult Ewing Sarcomas

scientific article published on 01 October 2017

The safety of chemotherapy for breast cancer patients with hepatitis C virus infection

scientific article published on 24 July 2013

The safety of chemotherapy for colorectal cancer patients with hepatitis C virus infection

scientific article published on 20 September 2014

Thioproline prevents carcinogenesis in the remnant stomach induced by duodenal reflux

scientific article published on 26 July 2005

Treatment Outcome of Second-Line Chemotherapy for Gynecologic Carcinosarcoma

scientific article published on 11 June 2020

Tremelimumab-associated tumor regression following after initial progression: two case reports

scientific article published on 02 October 2015

Tumour-infiltrating lymphocytes are correlated with higher expression levels of PD-1 and PD-L1 in early breast cancer.

scientific article

Visualization of HER2-specific breast cancer intratumoral heterogeneity using 64Cu-DOTA-trastuzumab PET.

scientific article

[Ifosfamide and Paclitaxel for Recurrent or Metastatic Uterine Carcinosarcoma]

scientific article published on 01 October 2019

[Ⅰ.Detecting Early Breast Cancer by Serum MicroRNA]

scientific article published on 01 December 2019

＜Editors' Choice＞ Practice management for elderly patients with breast cancer; Findings from a survey by the Japan Breast Cancer Study Group.

scientific article

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