List of works - Deborah Elstein

13,845 home therapy infusions with velaglucerase alfa exemplify safety of velaglucerase alfa and increased compliance to every-other-week intravenous enzyme replacement therapy for Gaucher disease

scientific article published on 21 September 2015

A Multicenter, Double-Blind, Randomized Safety and Efficacy Study of Two Dose Levels of Taliglucerase Alfa in Pediatric Patients with Gaucher Disease. ⬇️

scholarly article

A comprehensive assessment of renal function in patients with Gaucher disease

scientific article published in November 2005

Achievement of therapeutic goals with low-dose imiglucerase in Gaucher disease: a single-center experience

scientific article

Anesthetic management for oocyte retrieval: An exploratory analysis comparing outcome in in vitro fertilization cycles with and without pre-implantation genetic diagnosis

scientific article published on October 2013

Angiotensinogen promoter and angiotensinogen II receptor type 1 gene polymorphisms and incidence of ischemic stroke and neurologic phenotype in Fabry disease

scientific article published on 10 September 2013

Bone mineral density in gravida: effect of pregnancies and breast-feeding in women of differing ages and parity.

scientific article

Booster-effect with velaglucerase alfa in patients with Gaucher disease switched from long-term imiglucerase therapy: Early Access Program results from Jerusalem ⬇️

scientific article published on 01 November 2011

Children with type 1 Gaucher disease: Changing profiles in the 21st century

scientific article

Comparison of Bone Mineral Density by Dual-Energy X-Ray Absorptiometry and Bone Strength by Speed-of-Sound Ultrasonography in Adults With Gaucher Disease

scientific article published on 15 January 2016

Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes

scientific article

Demographics and patient characteristics of 1209 patients with Gaucher disease: Descriptive analysis from the Gaucher Outcome Survey (GOS).

scientific article published in November 2017

Dental profile of patients with Gaucher disease

scientific article

Disease severity in sibling pairs with type 1 Gaucher disease

scientific article published on 05 January 2010

Early access experience with VPRIV(®): recommendations for 'core data' collection.

scientific article published on 13 December 2010

Effect of enzyme replacement therapy on gammopathies in Gaucher disease

scientific article published on 01 January 2004

Effect of thrombocytopenia on mode of analgesia/anesthesia and maternal and neonatal outcomes

scientific article

Enzyme replacement therapy with velaglucerase alfa in Gaucher disease: Results from a randomized, double-blind, multinational, Phase 3 study

scientific article

Exploring the patient journey to diagnosis of Gaucher disease from the perspective of 212 patients with Gaucher disease and 16 Gaucher expert physicians

scientific article published on 04 August 2017

Gaucher disease and the clinical experience with substrate reduction therapy

scientific article

Gaucher disease in Arab patients at an Israeli referral clinic

scientific article published on 01 August 2008

Gaucher disease: pediatric concerns

scientific article

Gaucher disease: spectrum of sonographic findings in the liver

scientific article published in May 2010

Glucocerebroside: an evolutionary advantage for patients with Gaucher disease and a new immunomodulatory agent

scientific article published on 16 June 2009

Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients

scientific article

Growth and final height of children with Gaucher disease: A 15-year follow-up at an Israeli Gaucher center

scientific article

Iliopsoas haematoma in Gaucher disease

scientific article

Iliopsoas hematoma in a young patient with type I Gaucher disease

scientific article published on 01 September 2003

Impaired platelet function and peripartum bleeding in women with Gaucher disease

scientific article

Incidence of malignancies among patients with type I Gaucher disease from a single referral clinic.

scientific article published in May 2005

Increased prevalence of cholelithiasis in Gaucher disease: association with splenectomy but not with gilbert syndrome

scientific article published in August 2004

Management of Gaucher disease: enzyme replacement therapy

scientific article

Menetrier's disease presenting as an acute protein-losing gastroenteropathy in a 27-year-old man with Gaucher disease

scientific article published in June 2005

Multiple hypoechoic hepatic lesions in a patient with Gaucher disease

scientific article

N-brain natriuretic peptide: correlation with tricuspid insufficiency in Gaucher disease

scientific article published on 01 January 2004

National health budgets for expensive orphan drugs: Gaucher disease in Israel as a model

scientific article published on 07 July 2006

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

scientific article

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

scientific article

Organ volume by computed tomography correlates with longitudinal axis on ultrasound in patients with Gaucher disease

scientific article published in December 2011

Orthopedic considerations in Gaucher disease since the advent of enzyme replacement therapy

scientific article

Osteonecrosis in a patient with Gaucher's disease treated with enzyme replacement

scientific article published on 01 August 2003

Outcome of pregnancies in women receiving velaglucerase alfa for Gaucher disease

scientific article

Outcome of ten years' echocardiographic follow-up in children with Gaucher disease

scientific article published on 29 August 2006

Phenotypic heterogeneity in patients with Gaucher disease and the N370S/V394L genotype.

scientific article published in January 2005

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

scientific article

Platelet counts and interleukin-6 (IL-6) promoter polymorphism in patients with Gaucher disease

scientific article

Poor results of drilling in early stages of juxta-articular osteonecrosis in 12 joints affected by Gaucher disease.

scientific article

Pregnancies in Gaucher disease: a 5-year study

scientific article published on February 2004

Prevention of lysosomal storage diseases and derivation of mutant stem cell lines by preimplantation genetic diagnosis.

scientific article published on 26 December 2012

Proof-of-principle rapid noninvasive prenatal diagnosis of autosomal recessive founder mutations

scientific article

Proteinase-activated receptor (PAR1) polymorphic variant correlates with thrombocytopenia in Gaucher disease

scientific article

Pyrimethamine increases β-hexosaminidase A activity in patients with Late Onset Tay Sachs

scientific article

Repeat abdominal ultrasound evaluation of 100 patients with type I Gaucher disease treated with enzyme replacement therapy for up to 7 years

scientific article published on 01 January 2002

Retrospective audit of outcome of regional anesthesia for delivery in women with thrombocytopenia

scientific article

Review of the safety and efficacy of imiglucerase treatment of Gaucher disease

scientific article published on 15 September 2009

Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease

scientific article published on 7 November 2014

Safety and efficacy of velaglucerase alfa in Gaucher disease type 1 patients previously treated with imiglucerase.

scientific article published on 22 January 2013

Safety and efficacy results of switch from imiglucerase to velaglucerase alfa treatment in patients with type 1 Gaucher disease.

scientific article published in July 2015

Seven-year safety and efficacy with velaglucerase alfa for treatment-naïve adult patients with type 1 Gaucher disease

scientific article published on 28 May 2015

Spectrum of abdominal sonographic findings in 103 pediatric patients with Gaucher disease

scientific article published on 07 September 2001

Survey of hematological aspects of Gaucher disease

scientific article

Tc-99m sestamibi bone marrow scintigraphy in Gaucher disease

scientific article published on 01 July 2002

The 1604A (R496H) mutation in Gaucher disease: genotype/phenotype correlation

scientific article published in September 2003

The emergence of Parkinson disease among patients with Gaucher disease

scientific article published on 23 August 2014

The need for disease-specific patient-reported outcome measures for lysosomal disorders

The role of leptin in fetal growth: a short review from conception to delivery

scientific article published on 6 August 2007

Thromboelastography as a Surrogate Marker of Perisurgical Hemostasis in Gaucher Disease

scientific article

Treatment-naïve Gaucher disease patients achieve therapeutic goals and normalization with velaglucerase alfa by 4years in phase 3 trials

scientific article

Type I Gaucher disease in children with and without enzyme therapy

scientific article published on 01 September 2002

Uncomplicated outcome after anesthesia for pediatric patients with Gaucher disease

scientific article

Uveitis in Gaucher disease

scientific article

Velaglucerase alfa (VPRIV) enzyme replacement therapy in patients with Gaucher disease: Long-term data from phase III clinical trials.

scientific article

Zimran A, Brill-Almon E, Chertkoff R, et al. Pivotal trial with plant cell?expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease. Blood. 2011;118(22):.

scientific article published in May 2012

List of works by Deborah Elstein

13,845 home therapy infusions with velaglucerase alfa exemplify safety of velaglucerase alfa and increased compliance to every-other-week intravenous enzyme replacement therapy for Gaucher disease

A Multicenter, Double-Blind, Randomized Safety and Efficacy Study of Two Dose Levels of Taliglucerase Alfa in Pediatric Patients with Gaucher Disease. ⬇️

A comprehensive assessment of renal function in patients with Gaucher disease

Achievement of therapeutic goals with low-dose imiglucerase in Gaucher disease: a single-center experience

Anesthetic management for oocyte retrieval: An exploratory analysis comparing outcome in in vitro fertilization cycles with and without pre-implantation genetic diagnosis

Angiotensinogen promoter and angiotensinogen II receptor type 1 gene polymorphisms and incidence of ischemic stroke and neurologic phenotype in Fabry disease

Bone mineral density in gravida: effect of pregnancies and breast-feeding in women of differing ages and parity.

Booster-effect with velaglucerase alfa in patients with Gaucher disease switched from long-term imiglucerase therapy: Early Access Program results from Jerusalem ⬇️

Children with type 1 Gaucher disease: Changing profiles in the 21st century

Comparison of Bone Mineral Density by Dual-Energy X-Ray Absorptiometry and Bone Strength by Speed-of-Sound Ultrasonography in Adults With Gaucher Disease

Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes

Demographics and patient characteristics of 1209 patients with Gaucher disease: Descriptive analysis from the Gaucher Outcome Survey (GOS).

Dental profile of patients with Gaucher disease

Disease severity in sibling pairs with type 1 Gaucher disease

Early access experience with VPRIV(®): recommendations for 'core data' collection.

Effect of enzyme replacement therapy on gammopathies in Gaucher disease

Effect of thrombocytopenia on mode of analgesia/anesthesia and maternal and neonatal outcomes

Enzyme replacement therapy with velaglucerase alfa in Gaucher disease: Results from a randomized, double-blind, multinational, Phase 3 study

Exploring the patient journey to diagnosis of Gaucher disease from the perspective of 212 patients with Gaucher disease and 16 Gaucher expert physicians

Gaucher disease and the clinical experience with substrate reduction therapy

Gaucher disease in Arab patients at an Israeli referral clinic

Gaucher disease: pediatric concerns

Gaucher disease: spectrum of sonographic findings in the liver

Glucocerebroside: an evolutionary advantage for patients with Gaucher disease and a new immunomodulatory agent

Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients

Growth and final height of children with Gaucher disease: A 15-year follow-up at an Israeli Gaucher center

Iliopsoas haematoma in Gaucher disease

Iliopsoas hematoma in a young patient with type I Gaucher disease

Impaired platelet function and peripartum bleeding in women with Gaucher disease

Incidence of malignancies among patients with type I Gaucher disease from a single referral clinic.

Increased prevalence of cholelithiasis in Gaucher disease: association with splenectomy but not with gilbert syndrome

Management of Gaucher disease: enzyme replacement therapy

Menetrier's disease presenting as an acute protein-losing gastroenteropathy in a 27-year-old man with Gaucher disease

Multiple hypoechoic hepatic lesions in a patient with Gaucher disease

N-brain natriuretic peptide: correlation with tricuspid insufficiency in Gaucher disease

National health budgets for expensive orphan drugs: Gaucher disease in Israel as a model

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

Organ volume by computed tomography correlates with longitudinal axis on ultrasound in patients with Gaucher disease

Orthopedic considerations in Gaucher disease since the advent of enzyme replacement therapy

Osteonecrosis in a patient with Gaucher's disease treated with enzyme replacement

Outcome of pregnancies in women receiving velaglucerase alfa for Gaucher disease

Outcome of ten years' echocardiographic follow-up in children with Gaucher disease

Phenotypic heterogeneity in patients with Gaucher disease and the N370S/V394L genotype.

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

Platelet counts and interleukin-6 (IL-6) promoter polymorphism in patients with Gaucher disease

Poor results of drilling in early stages of juxta-articular osteonecrosis in 12 joints affected by Gaucher disease.

Pregnancies in Gaucher disease: a 5-year study

Prevention of lysosomal storage diseases and derivation of mutant stem cell lines by preimplantation genetic diagnosis.

Proof-of-principle rapid noninvasive prenatal diagnosis of autosomal recessive founder mutations

Proteinase-activated receptor (PAR1) polymorphic variant correlates with thrombocytopenia in Gaucher disease

Pyrimethamine increases β-hexosaminidase A activity in patients with Late Onset Tay Sachs

Repeat abdominal ultrasound evaluation of 100 patients with type I Gaucher disease treated with enzyme replacement therapy for up to 7 years

Retrospective audit of outcome of regional anesthesia for delivery in women with thrombocytopenia

Review of the safety and efficacy of imiglucerase treatment of Gaucher disease

Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease

Safety and efficacy of velaglucerase alfa in Gaucher disease type 1 patients previously treated with imiglucerase.

Safety and efficacy results of switch from imiglucerase to velaglucerase alfa treatment in patients with type 1 Gaucher disease.

Seven-year safety and efficacy with velaglucerase alfa for treatment-naïve adult patients with type 1 Gaucher disease

Spectrum of abdominal sonographic findings in 103 pediatric patients with Gaucher disease

Survey of hematological aspects of Gaucher disease

Tc-99m sestamibi bone marrow scintigraphy in Gaucher disease

The 1604A (R496H) mutation in Gaucher disease: genotype/phenotype correlation

The emergence of Parkinson disease among patients with Gaucher disease

The need for disease-specific patient-reported outcome measures for lysosomal disorders

The role of leptin in fetal growth: a short review from conception to delivery

Thromboelastography as a Surrogate Marker of Perisurgical Hemostasis in Gaucher Disease

Treatment-naïve Gaucher disease patients achieve therapeutic goals and normalization with velaglucerase alfa by 4years in phase 3 trials

Type I Gaucher disease in children with and without enzyme therapy

Uncomplicated outcome after anesthesia for pediatric patients with Gaucher disease

Uveitis in Gaucher disease

Velaglucerase alfa (VPRIV) enzyme replacement therapy in patients with Gaucher disease: Long-term data from phase III clinical trials.

Zimran A, Brill-Almon E, Chertkoff R, et al. Pivotal trial with plant cell?expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease. Blood. 2011;118(22):.