List of works - Nathaniel Heintz

5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes.

scientific article published on 28 August 2017

A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors

scientific article published on 14 September 2016

A High-Resolution Genetic Map of the Nervous Locus on Mouse Chromosome 8 ⬇️

scientific article published on March 15, 1998

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

scientific article (publication date: 30 October 2003)

A multilocus linkage map of mouse chromosome 8.

scientific article published in April 1991

A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase

scientific journal article

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

scientific article (publication date: 29 August 2002)

A role for LYNX2 in anxiety-related behavior

scientific article

A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R.

scientific article

A translational profiling approach for the molecular characterization of CNS cell types

scientific article (publication date: 14 November 2008)

Acute Cocaine Induces Fast Activation of D1 Receptor and Progressive Deactivation of D2 Receptor Striatal Neurons:In VivoOptical Microprobe [Ca2+]iImaging ⬇️

scientific article published on September 14, 2011

Amygdala inhibitory neurons as loci for translation in emotional memories

scientific article published on 07 October 2020

Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis

scientific article

Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells

scientific article

Application of a translational profiling approach for the comparative analysis of CNS cell types

scientific article published on November 2008

Autophagy and its possible roles in nervous system diseases, damage and repair

scientific article

BAC Transgenic Mice and the GENSAT Database of Engineered Mouse Strains ⬇️

scientific article published on March 1, 2013

BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin

scientific article

Bac to the future: The use of bac transgenic mice for neuroscience research ⬇️

scientific article published on December 1, 2001

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

scientific article (publication date: October 2014)

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

scientific article

Biomedicine. Ataxin-1 regulators in the spotlight

scientific article published on July 2003

Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells

scientific article

Cell death and the cell cycle: a relationship between transformation and neurodegeneration?

scientific article published on May 1993

Cell type-specific expression of a human histone H1 gene

scientific article published on 01 February 1988

Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP).

scientific article

Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

scientific article published on 11 July 2008

Cell-cycle-regulated phosphorylation of the transcription factor Oct-1.

scientific article published in January 1991

Cell-type specific contributions of medial prefrontal neurons to flexible behaviors.

scientific article published on 12 April 2018

Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area.

scientific article published on 30 July 2009

Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation

scientific article published on 20 January 2020

Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro

scientific article published in May 1991

Changing Patterns of Gene Expression Identify Multiple Steps During Regression of Rat Prostate in Vivo ⬇️

scientific article published on June 1, 1998

Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation

scientific article published on January 1993

Characterization and functional expression of a cDNA encoding egasyn (esterase-22): the endoplasmic reticulum-targeting protein of β-glucuronidase ⬇️

scientific article published on December 1, 1991

Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices

scientific article published on 30 October 2010

Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior ⬇️

scientific article published on June 25, 2012

Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit

scientific article published on January 2014

Coxsackievirus B-3-induced myocarditis. Virus and actinomycin D treatment of myocytes induces novel antigens recognized by cytolytic T lymphocytes

scientific article published in November 1988

Cre-ating somatic cell genetic mosaics in the mouse

scientific article published in May 2005

Defining the expression pattern of the LGI1 gene in BAC transgenic mice

scientific article

Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation

scientific article

Developmental biology: survival by self-digestion

scientific article published in December 2004

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

scientific article

Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum

journal article published in 2008

Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain

scientific article published on June 2007

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

scientific article

Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

scientific article published on 21 July 2004

Examination of Bacterial Artificial Chromosome (BAC) DNA Quality and Quantity by Pulsed-Field Gel Electrophoresis

scientific article published on 01 November 2019

Expression of brain lipid binding protein in the brain of the adult canary and its implications for adult neurogenesis ⬇️

scientific article published on September 1, 1997

Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.

scientific article

GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits

scientific article published on December 2013

Gene expression nervous system atlas (GENSAT).

scientific article

Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6.

scientific article published on November 1995

Genes involved in cerebellar cell specification and differentiation

scientific article published on February 1997

Genetic address book for retinal cell types

scientific article published on 2 August 2009

Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development

scientific article published on 5 November 2008

Genetic mapping of meander tail, a mouse mutation affecting cerebellar development

scientific article published in April 1991

GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice

scientific article

Growth of Saccharomyces cerevisiae and Preparation of DNA

scientific article published on 01 October 2020

Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication

scientific article

Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome ⬇️

scientific article published on September 1, 1997

How neurons keep in touch

scientific article published on 01 November 2005

Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity

scientific article

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

scientific article

Identification of the cortical neurons that mediate antidepressant responses

scientific article

In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors

scientific article

Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels

scientific article published in April 2004

Induction of autophagy in axonal dystrophy and degeneration

scientific journal article

Infected digital burns

scientific article published on November 1, 1974

Insights from mouse models into the molecular basis of neurodegeneration

scientific article

Large-Scale Preparation and Linearization of Bacterial Artificial Chromosome (BAC) DNA

scientific article published on 01 November 2019

Large-scale genomic approaches to brain development and circuitry

scientific article

Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors

scientific article

Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus

scientific journal article

Lynx1, a cholinergic brake, limits plasticity in adult visual cortex

scientific article

Malignant transformation of cultured rat hepatocytes by (+)- and (-)-trans-7,8-dihydro-7,8-dihydroxybenzo(a)pyrene.

scientific article published in April 1980

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

scientific article published on December 2012

MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system.

scientific article

MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions

scientific article published on 23 December 2019

Mechanisms of Neural Patterning and Specification in the Development Cerebellum ⬇️

scientific article published on January 1, 1995

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice

scientific article

Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity ⬇️

scientific article published on December 20, 1991

Modified bacterial artificial chromosomes for zebrafish transgenesis

scientific article published in July 2006

Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus.

scientific article

Mouse transgenesis in a single locus with independent regulation for multiple fluorophores

scientific article

Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor gene ⬇️

scientific article published on August 21, 1997

Nitric oxide regulates synaptic transmission between spiny projection neurons

scientific journal article

Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1

scientific journal article

One-Step Bacterial Artificial Chromosome (BAC) Modification: Cloning of the A Homology Arm into Reporter-Shuttle Vector

scientific article published on 01 July 2020

One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of Plasmids

scientific article published on 01 July 2020

One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of the A Homology Arm (A-Box)

scientific article published on 01 July 2020

One-Step Bacterial Artificial Chromosome (BAC) Modification: Transfer of the Reporter Vector into BAC/RecA Cells and Selection of Co-Integrates

scientific article published on 01 July 2020

One-Step Bacterial Artificial Chromosome (BAC) Modification: Transformation of the BAC Host with the RecA Vector

scientific article published on 01 July 2020

One-hit neuronal death

scientific article published in Nature

Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons

scientific article

Parallel ascending spinal pathways for affective touch and pain

scientific article published on 28 October 2020

Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

scientific article published in May 2005

Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse

scientific article

Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons.

scientific article

Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2.

scientific article published on December 1988

Radial glia serve as neuronal progenitors in all regions of the central nervous system

scientific article published in March 2004

Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP

scientific article

Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis ⬇️

scientific article published on September 30, 2010

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.

scientific article

Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference.

scientific article published on 20 November 2017

Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis

scientific article published on 24 June 2020

Skeletal dystrophies in Recklinghausen's neurofibromatosis

scientific article published in October 1969

Small-Scale Isolation of Bacterial Artificial Chromosome (BAC) DNA and Verification by Polymerase Chain Reaction (PCR)

scientific article published on 01 November 2019

Small-Scale Preparations of Yeast DNA

scientific article published on 06 August 2020

Species and cell-type properties of classically defined human and rodent neurons and glia

scientific article published on 15 October 2018

Squamous Metaplasia of the Tracheal Epithelium in Organ Culture. II. Nutritional Influences ⬇️

scientific article published on March 1, 1978

Squamous cell carcinoma of the cervix: HPV 16 and DNA ploidy as predictors of survival

scientific article published on September 1, 1992

Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice

scientific article

Study on rehabilitation-reeducation

scientific article published on 01 June 1965

Surgery of coxarthrosis

scientific article published on 01 March 1970

Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs

scientific article published on 01 September 2007

Temporal regulation of gene expression during the mammalian cell cycle

scientific article published on April 1989

Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo

scientific article published on 01 August 2004

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn.

scientific article

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons ⬇️

scientific article published on December 23, 2011

The Lurcher Mutation and Ionotropic Glutamate Receptors: Contributions to Programmed Neuronal Death In vivo ⬇️

scientific article published on October 1, 1998

The biochemical anatomy of cortical inhibitory synapses

scientific article

The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors

scientific article

The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects

scientific article published in January 2007

The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake

scientific article published on 25 February 2020

The knockout mouse project

scientific article

The lurcher gene induces apoptotic death in cerebellar Purkinje cells

scientific article published on 01 April 1995

The neuron identity problem: form meets function

scientific article published in October 2013

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

scientific article

The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo

scientific article published in September 2006

To beat or not to beat: roles of cilia in development and disease

scientific article

Transcription Factor OTF-1 Is Functionally Identical to the DNA Replication Factor NF-III ⬇️

scientific article published on September 2, 1988

Transcriptional regulation in the eukaryotic cell cycle ⬇️

scientific article published on November 1, 1991