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List of works by Hong Zhu

2-Bromopalmitate sensitizes osteosarcoma cells to adriamycin-induced apoptosis via the modulation of CHOP

scientific article published on 12 December 2018

ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner

scientific article published on 19 October 2018

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.

scientific article published on 4 December 2017

AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer.

scientific article published in January 2018

ATF4 regulates CCL2 expression to promote endometrial cancer growth by controlling macrophage infiltration.

scientific article published on 23 August 2017

Activation of Caspase-2 in Apoptosis

scientific article published on August 22, 1997

Aldo-Keto Reductase AKR1C1-AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy.

scientific article published on 14 March 2017

Baicalein Triggers Autophagy and Inhibits the Protein Kinase B/Mammalian Target of Rapamycin Pathway in Hepatocellular Carcinoma HepG2 Cells.

scientific article published on 14 January 2015

Bisphenol A deteriorates egg quality through HDAC7 suppression.

scientific article

CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation.

scientific article published on 16 September 2016

Cap-dependent translation initiation factor, eIF4E, is the target for Ouabain-mediated inhibition of HIF-1α.

scientific article

Caspase-11 controls interleukin-1β release through degradation of TRPC1.

scientific article

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

scientific article

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

scientific article

Cryptotanshinone Induces Pro-death Autophagy through JNK Signaling Mediated by Reactive Oxygen Species Generation in Lung Cancer Cells.

scientific article published on 6 September 2015

DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal.

scientific article published on 26 March 2014

Deubiquitinating enzyme USP10 promotes hepatocellular carcinoma metastasis through deubiquitinating and stabilizing Smad4 protein

scientific article published on 27 November 2019

Dihydromyricetin prevents cardiotoxicity and enhances anticancer activity induced by adriamycin

scientific article published on February 2015

Drug Combination in Clinical Cancer Treatments.

scientific article published on 03 August 2017

Enhanced anti-tumor activity by the combination of TRAIL/Apo-2L and combretastatin A-4 against human colon cancer cells via induction of apoptosis in vitro and in vivo

scientific article published on January 14, 2011

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L

scientific article published on 30 March 2015

GL3, a Novel 4β-Anilino-4'-O-Demethyl-4-Desoxypodophyllotoxin Analog, Traps Topoisomerase II Cleavage Complexes and Exerts Anticancer Activities.

scientific article published on February 2013

Glycyrrhetinic Acid triggers a protective autophagy by activation of extracellular regulated protein kinases in hepatocellular carcinoma cells

scientific article

Harmine suppresses the proliferation and migration of human ovarian cancer cells through inhibiting ERK/CREB pathway.

scientific article

Hypoxia-Targeted Drug Q6 Induces G2-M Arrest and Apoptosis via Poisoning Topoisomerase II under Hypoxia

scientific article

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

scientific journal article

Identification of PRDX6 as a regulator of ferroptosis

scientific article published on 29 April 2019

Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells

scientific article published on August 2016

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

scientific journal article

Inhibition of M2-like macrophages by all-trans retinoic acid prevents cancer initiation and stemness in osteosarcoma cells

scientific article published on 11 July 2019

Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells.

scientific article published on 24 February 2016

Kelch-like proteins: Physiological functions and relationships with diseases

scientific article published on 20 August 2019

Knockdown of Nucleostemin in an ovarian cancer SKOV-3 cell line and its effects on cell malignancy.

scientific article

LncRNA-MM2P Identified as a Modulator of Macrophage M2 Polarization

scientific article published on 20 November 2018

MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells

scientific article published on 17 August 2017

Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis

scientific article published on 18 April 2018

Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.

scientific article

Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor

scientific article published on 12 July 2017

Nutlin-3 inhibits epithelial-mesenchymal transition by interfering with canonical transforming growth factor-β1-Smad-Snail/Slug axis

scientific article published on 31 August 2013

Ougan (Citrus reticulata cv. Suavissima) flavedo extract suppresses cancer motility by interfering with epithelial-to-mesenchymal transition in SKOV3 cells

scientific article published on 27 June 2015

Oxidative stress is involved in Dasatinib-induced apoptosis in rat primary hepatocytes

scientific article published on April 17, 2012

Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells

scientific article

Polysarcosine brush stabilized gold nanorods for in vivo near-infrared photothermal tumor therapy.

scientific article

Post-translational modification of retinoic acid receptor alpha and its roles in tumor cell differentiation

scientific article published on 11 November 2019

Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma

scientific article

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.

scientific article published in February 2007

RETRACTED: Aberrant Sialylation in Cancer Pathology and Metastasis, a Putative Drug Target Candidate

retracted scientific article published on 01 January 2018

RIPK1 mediates a disease-associated microglial response in Alzheimer's disease

scientific article published on 13 September 2017

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

scientific article

Resistance of SMMC-7721 hepatoma cells to etoposide in hypoxia is reversed by VEGF inhibitor.

scientific article

SMT-A07, a 3-(Indol-2-yl) indazole derivative, induces apoptosis of leukemia cells in vitro

scientific article published on August 6, 2010

SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.

scientific article published on 12 July 2017

Simultaneous NF-κB inhibition and E-cadherin upregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo.

scientific article

Stress granule: A promising target for cancer treatment

scientific article published on 08 November 2019

Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway

scientific article published on November 9, 2010

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

scientific article published on 23 August 2018

Targeting slug-mediated non-canonical activation of c-Met to overcome chemo-resistance in metastatic ovarian cancer cells.

scientific article published on 2 March 2019

The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα.

scientific article published on 18 January 2016

The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor

scientific article

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

scientific article

The discovery and optimization of novel dual inhibitors of topoisomerase II and histone deacetylase.

scientific article published on 18 September 2013

The dual PI3K/mTOR inhibitor NVP-BEZ235 prevents epithelial-mesenchymal transition induced by hypoxia and TGF-β1.

scientific article published on 20 February 2014

The involvement of M2 macrophage polarization inhibition in fenretinide-mediated chemopreventive effects on colon cancer

scientific article published on 29 November 2016

The posttranslational modifications of Hippo-YAP pathway in cancer

scientific article published on 12 July 2019

Thiazolidenediones induce tumour-cell apoptosis through the Akt-GSK3β pathway

scientific article published on March 16, 2011

Tirapazamine sensitizes hepatocellular carcinoma cells to topoisomerase I inhibitors via cooperative modulation of hypoxia-inducible factor-1α.

scientific article published on 20 December 2013