Search filters

List of works by Steven B Marston

'(De-)sensitization' vs. 'Uncoupling': what drives cardiomyopathies in the thin filament? Reply.

scientific article

A dilated cardiomyopathy mutation blunts adrenergic response and induces contractile dysfunction under chronic angiotensin II stress

scientific article

A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation

scientific article published on 27 May 2016

Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes

scientific article published in November 2017

Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.

scientific article published on 8 September 2017

Axial distribution of myosin binding protein-C is unaffected by mutations in human cardiac and skeletal muscle ⬇️

scientific article published on March 14, 2012

Characterization of the functional properties of smooth muscle caldesmon domain 4a: evidence for an independent inhibitory actin–tropomyosin binding domain ⬇️

scientific article published on June 1, 1998

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

scientific article published on 23 September 2020

Donor hearts in the Sydney Heart Bank: reliable control but is it 'normal' heart?

scientific article published on 20 July 2020

How Do Mutations in Contractile Proteins Cause the Primary Familial Cardiomyopathies? ⬇️

scientific article published on March 22, 2011

How do MYBPC3 mutations cause hypertrophic cardiomyopathy? ⬇️

scientific article published on November 5, 2011

In Vitro Motility Analysis of Smooth Muscle Caldesmon Control of Actin-Tropomyosin Filament Movement ⬇️

scientific article published on August 25, 1995

Inhibition of actin-tropomyosin activation of myosin MgATPase activity by the smooth muscle regulatory protein caldesmon ⬇️

scientific article published on August 25, 1992

Instrumentation to study myofibril mechanics from static to artificial simulations of cardiac cycle.

scientific article published on 2 March 2016

Interaction of isoforms of S100 protein with smooth muscle caldesmon ⬇️

scientific article published on January 30, 1998

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus).

scientific article

Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits

scientific article published on 01 November 2018

Location and functional characterization of myosin contact sites in smooth- muscle caldesmon ⬇️

scientific article published on November 15, 1997

Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin.

scientific article published on 27 March 2018

Molecular Mechanism of the E99K Mutation in Cardiac Actin (ACTC Gene) That Causes Apical Hypertrophy in Man and Mouse ⬇️

scientific article published on May 26, 2011

Muscle weakness in TPM3-myopathy is due to reduced Ca2+-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres

scientific article

Mutations in repeating structural motifs of tropomyosin cause gain of function in skeletal muscle myopathy patients ⬇️

scientific article published on July 25, 2013

Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation

scientific article published on 29 March 2016

Myopathy-inducing mutation H40Y in ACTA1 hampers actin filament structure and function

scientific article published on 22 April 2016

Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease

scientific article published on 25 March 2013

OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency.

scientific article published on 25 September 2015

Obscurin variants and inherited cardiomyopathies.

scientific article published on 5 May 2017

Pressure Overload Is Associated With Low Levels of Troponin I and Myosin Binding Protein C Phosphorylation in the Hearts of Patients With Aortic Stenosis

scientific article published on 19 March 2020

Skeletal muscle myopathy mutations at the actin tropomyosin interface that cause gain- or loss-of-function ⬇️

scientific article published on May 30, 2013

Small Molecules acting on Myofilaments as Treatments for Heart and Skeletal Muscle Diseases

scientific article published on 16 December 2020

Small molecule studies: the fourth wave of muscle research

scientific article published on 21 June 2019

TPM3 deletions cause a hypercontractile congenital muscle stiffness phenotype

scientific article published on 29 September 2015

Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics

scientific article published on 23 July 2018

The European Muscle Conference 2019 Special Issue

scientific article published on 01 June 2019

The Importance of Intrinsically Disordered Segments of Cardiac Troponin in Modulating Function by Phosphorylation and Disease-Causing Mutations

scientific article

The Molecular Mechanisms of Mutations in Actin and Myosin that Cause Inherited Myopathy.

scientific article

The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.

scientific article published on 14 August 2017

The dilated cardiomyopathy-causing mutation ACTC E361G in cardiac muscle myofibrils specifically abolishes modulation of Ca(2+) regulation by phosphorylation of troponin I

scientific article

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

scientific article published on 21 December 2018

The use of phosphate‐affinity SDS‐PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle ⬇️

scientific article published on October 13, 2009

Tropomyosin Must Interact Weakly with Actin to Effectively Regulate Thin Filament Function.

scientific article published in December 2017

Troponin I and troponin T interact with troponin C to produce different Ca2+-dependent effects on actin–tropomyosin filament motility ⬇️

scientific article published on October 15, 1997

Troponin structure and function: a view of recent progress

scientific article published on 27 April 2019

Troponin structure: its modulation by Ca(2+) and phosphorylation studied by molecular dynamics simulations.

scientific article published on 14 July 2016

Why Is there a Limit to the Changes in Myofilament Ca2+-Sensitivity Associated with Myopathy Causing Mutations?

scientific article

Paulina is supported by:

About Paulina

Help