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List of works by Serge Roche

ABL tyrosine kinase inhibition variable effects on the invasive properties of different triple negative breast cancer cell lines.

scientific article

Analysis of SRC Oncogenic Signaling in Colorectal Cancer by Stable Isotope Labeling with Heavy Amino Acids in Mouse Xenografts ⬇️

scientific article published on September 29, 2012

Analysis of oncogenic signaling induced by tyrosine kinases in tumors by SILAC-based quantitative proteomic approach

scientific article

CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia.

scientific article published on 4 June 2015

Characterization of two different cytoplasmic protein tyrosine kinases from human breast cancer ⬇️

scientific article published on August 1, 1997

Collagen Kinase Receptors as Potential Therapeutic Targets in Metastatic Colon Cancer

scientific article published on 12 February 2020

Contribution of phosphoproteomics in understanding SRC signaling in normal and tumor cells.

scientific article

Control of Tyrosine Kinase Signalling by Small Adaptors in Colorectal Cancer.

scientific article published on 14 May 2019

DDR1 inhibition as a new therapeutic strategy for colorectal cancer

scientific article published on 23 July 2018

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

scientific article published on 27 February 2018

Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

scientific article published on 01 November 2018

Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

scientific article published on 9 February 2018

Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity ⬇️

scientific article published on October 16, 2003

Oncogenic signaling by tyrosine kinases of the SRC family in advanced colorectal cancer ⬇️

scientific article published on June 28, 2012

Progastrin a new pro-angiogenic factor in colorectal cancer

scientific article published on 11 August 2014

Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells ⬇️

scientific article published on July 5, 2011

Roles of exosomes in metastatic colorectal cancer

scientific article published on 10 July 2019

SHEDding light on the role of Pragmin pseudo-kinases in cancer

scientific article published on 01 February 2019

SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.

scientific article published in January 2014

Src Family Tyrosine Kinase Regulates Intracellular pH in Cardiomyocytes ⬇️

scientific article published on June 29, 1998

Src Family Tyrosine Kinases in Intestinal Homeostasis, Regeneration and Tumorigenesis

scientific article published on 23 July 2020

Src and Ras are involved in separate pathways in epithelial cell scattering ⬇️

scientific article published on October 1, 1997

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis ⬇️

scientific article published on August 27, 1998

Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells

scientific article published on 25 March 2014

Syntenin mediates SRC function in exosomal cell-to-cell communication

scientific article published on 6 November 2017

TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.

scientific article

The SH3 Domain Acts as a Scaffold for the N-Terminal Intrinsically Disordered Regions of c-Src.

scientific article published on 23 April 2015

The Unique Domain Forms a Fuzzy Intramolecular Complex in Src Family Kinases

scientific article published on 16 March 2017

The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer

scientific article

Tyrosine kinases of the Src family, enzymes with multiple functions: from the growth of fibroblasts to the migration of epithelial cells

scientific article published on 01 January 1998

Vesicular trafficking regulators are new players in breast cancer progression: Role of TOM1L1 in ERBB2-dependent invasion.

scientific article published on 28 April 2016

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