Search filters

List of works by Alejandro Villagra

A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs.

scientific article

Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

scientific article published on 10 October 2019

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article

Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity

scientific article

Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

scientific article published on 04 September 2019

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

scientific article

Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.

scientific article published on 10 March 2014

Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.

scientific article published on 27 January 2013

Epigenetic therapy for ovarian cancer: promise and progress

scientific article published on 15 January 2019

Erratum to: Functional Analysis of Histone Deacetylase 11 (HDAC11)

scientific article published on 01 January 2016

Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.

scientific article published on 26 May 2017

Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancies

scientific article published in January 2016

Functional Analysis of HDACs in Tumorigenesis

scientific article published on 01 January 2019

Functional Analysis of Histone Deacetylase 11 (HDAC11).

scientific article published on January 2016

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade.

scientific article

HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer

scientific article published on 30 June 2020

Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function

scientific article

Immunoepigenetics Combination Therapies: An Overview of the Role of HDACs in Cancer Immunotherapy. ⬇️

scientific article published on 7 May 2019

Indocyanine Green-Nexturastat A-PLGA Nanoparticles Combine Photothermal and Epigenetic Therapy for Melanoma

scientific article published on 17 January 2020

Modulation of antigen‐presenting cells by HDAC inhibitors: implications in autoimmunity and cancer ⬇️

scientific article published on November 22, 2011

Phase I trial of histone deacetylase inhibitor panobinostat in addition to glucocorticoids for primary therapy of acute graft-versus-host disease

scientific article published on 18 April 2018

Preparation and Biochemical Analysis of Classical Histone Deacetylases.

scientific article

Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts

scientific article

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

scientific article published on August 2009

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

scientific article published on 16 April 2019

Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.

scientific article

Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia

scientific article published on 01 November 2018

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity ⬇️

scientific article published on June 22, 2012

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

scientific article published on 5 September 2017

T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.

scientific article published on 26 May 2017

Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.

scientific article published on 24 April 2015

Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment.

scientific article published on 7 August 2017

The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity.

scientific article published on October 2013

c-Abl stabilizes HDAC2 levels by tyrosine phosphorylation repressing neuronal gene expression in Alzheimer's disease

scientific article published on 11 September 2014

Paulina is supported by:

About Paulina

Help