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List of works by Anjana Rao

'Nurr'ishing Treg cells: Nr4a transcription factors control Foxp3 expression ⬇️

scientific article published on March 1, 2013

5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells

scientific article published on 10 November 2020

A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.

scholarly article

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells

scientific article published on 01 July 2002

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo.

scientific article

A Distal Enhancer in the Interferon-γ (IFN-γ) Locus Revealed by Genome Sequence Comparison ⬇️

scientific article published on 08 November 2003

A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.

scientific article published on May 2004

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

scientific article

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

scientific article published in January 2005

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

scientific article

A plague of autoantibodies

scientific article published on 01 July 2005

A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways

scientific article published on 14 March 2016

A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients

scientific article

A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.

scientific article

Aberrant T cell differentiation in the absence of Dicer.

scientific article

Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling.

scientific article published in August 2004

Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength

scientific article published on 03 June 2020

Acute loss of TET function results in aggressive myeloid cancer in mice

scientific article

Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.

scientific article published on 14 March 2013

Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells

scientific article published on 06 April 2020

An asymmetric NFAT1 dimer on a pseudo-palindromic kappa B-like DNA site

scientific article

An epigenetic view of helper T cell differentiation

scientific article

An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia

scientific article published on 20 April 2020

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry

scientific article published on 23 June 2013

BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells

scientific article published on 19 July 2021

Biochemical and functional characterization of Orai proteins

scientific article published on 9 February 2007

Bioinformatics for the 'bench biologist': how to find regulatory regions in genomic DNA.

scientific article

Ca2+/calcineurin signalling in cells of the immune system ⬇️

scientific article published on November 28, 2003

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

scientific article

Calcineurin: From structure to function

scientific article published in 2001

Calcium signaling in cells of the immune and hematopoietic systems

scientific article published on 01 September 2009

Calcium signaling in lymphocytes

scientific article

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex

scientific article

Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells

scientific article published on 30 September 2005

Chromatin-level regulation of the IL10 gene in T cells.

scientific article

Chromosome transfer activates and delineates a locus control region for perforin

scientific article published on 11 January 2007

Connections between TET proteins and aberrant DNA modification in cancer

scientific article

Control of Foxp3 stability through modulation of TET activity

scientific article published on 22 February 2016

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

scientific article

Correction: Domain Requirements and Sequence Specificity of DNA Binding for the Forkhead Transcription Factor FOXP3.

scientific article

Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

scientific article published on August 2004

Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection

scientific article published on 05 February 2016

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

scientific article

DNA Translocation through Hybrid Bilayer Nanopores

scientific article published on 23 April 2019

DNA methylation and hydroxymethylation in hematologic differentiation and transformation

scientific article

DNA methylation and methylcytosine oxidation in cell fate decisions

scientific article published on 14 March 2013

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

scientific article published on 18 July 2016

DNMT3A and TET2 mutations reshape hematopoiesis in opposing ways

scientific article published on 01 June 2020

Defining 'T cell exhaustion'

scientific article published on 30 September 2019

Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling

scientific article

Deletion of a conserved Il4 silencer impairs T helper type 1–mediated immunity

scientific article published on 31 October 2004

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex ⬇️

scientific article published on June 27, 2011

Dissecting ICRAC, a store-operated calcium current

scientific article

Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation

scientific article

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells

scientific article published on 13 January 2014

Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3

scientific article

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

scientific article

Dynamic Changes in Chromatin Accessibility Occur in CD8+ T Cells Responding to Viral Infection.

scientific article published on 5 December 2016

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps

scientific article

Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies

scientific article published on 01 October 2019

E3 ligases in T cell anergy--turning immune responses into tolerance

scientific article published on 6 July 2004

Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages

scientific article

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

scientific article

Erratum: The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection

scientific article published on September 2017

Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells

scientific article published on 10 March 2017

FOXP3 controls regulatory T cell function through cooperation with NFAT

scientific article

Foxp1 is an essential transcriptional regulator of B cell development

scientific journal article

Gene regulation and signal transduction in the immune system

scientific article published on 10 July 2008

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

scientific article

Global epigenomic reconfiguration during mammalian brain development

scientific article (publication date: 9 August 2013)

Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules ⬇️

scientific article published on March 14, 2013

HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

scientific article published on 01 March 2020

HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells

scientific article published on 02 December 2019

Hair loss and defective T- and B-cell function in mice lacking ORAI1

scientific article

Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase

scientific article

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

scientific article

Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation.

scientific article published on 31 January 2014

Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells

scientific article

High-resolution nucleosome mapping of targeted regions using BAC-based enrichment ⬇️

scientific article published on February 14, 2013

Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis

scientific article

Identification of a c-myb attenuator-binding factor

scientific article published in February 2002

Immunological applications of genomics

scientific article published on January 2006

Immunology. Cooperative transcription factor complexes in control

scientific article published on November 2012

Immunology. Opposites attract in differentiating T cells

scientific article published on 01 June 2005

Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression

scientific article published on 15 November 2018

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

scientific article

In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation

scientific article

Inhibition of the calcineurin-NFAT interaction by small organic molecules reflects binding at an allosteric site

scientific article

Initial activation of STIM1, the regulator of store-operated calcium entry

scientific article

Interaction of calcineurin with substrates and targeting proteins

scientific article

Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

scientific article

Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V

scientific article published on 9 February 2012

Introduction to COI volume on lymphocyte activation 2008

scientific article published on 12 June 2008

Involvement of NFAT1 in B cell self-tolerance

scientific article published on 01 August 2006

Itching to end NF-kappaB.

scientific article

Jarid2 is induced by TCR signalling and controls iNKT cell maturation.

scientific article

Large conserved domains of low DNA methylation maintained by Dnmt3a

scientific article published on 24 November 2013

Leveraging premalignant biology for immune-based cancer prevention

scientific article published on 16 September 2016

Lineage-specific expansions of TET/JBP genes and a new class of DNA transposons shape fungal genomic and epigenetic landscapes

scientific article

Lineage-specific functions of TET1 in the postimplantation mouse embryo.

scientific article

Linking calcineurin activity to leukemogenesis

scientific article published on 01 June 2007

Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression

scientific article

Loss of TET2 and TET3 in regulatory T cells unleashes effector function

scientific article published on 01 May 2019

LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs

scientific article

MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions

scientific article published on 23 December 2019

Mechanism of Antifungal Activity of Terpenoid Phenols Resembles Calcium Stress and Inhibition of the TOR Pathway ⬇️

scientific article published on October 4, 2010

MicroRNA profiling of the murine hematopoietic system

scientific article

MicroRNA-221-222 regulate the cell cycle in mast cells

scientific article

MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation

scientific article published on 25 October 2013

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

scientific article published on 7 April 2013

Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3.

scholarly article

Molecular basis of calcium signaling in lymphocytes: STIM and ORAI

scientific article

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

scientific journal article

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.

scientific article

Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis

scientific article published on 10 July 2017

NFAT, immunity and cancer: a transcription factor comes of age ⬇️

scientific article published on August 20, 2010

NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription

scientific article published in October 2002

NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia

scientific article published on 2 October 2017

NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone

scientific article

NR4A transcription factors limit CAR T cell function in solid tumours

scientific article published on 27 February 2019

New functions for DNA modifications by TET-JBP.

scientific article published on November 2012

New twists of T cell fate: control of T cell activation and tolerance by TGF-beta and NFAT.

scientific article published on 12 April 2007

Nontargeted Nucleotide Analysis Based on Benzoylhistamine Labeling-MALDI-TOF/TOF-MS: Discovery of Putative 6-Oxo-Thymine in DNA ⬇️

scientific article published on April 2, 2012

O-GlcNAcylation and 5-Methylcytosine Oxidation: An Unexpected Association between OGT and TETs ⬇️

scientific article published on February 21, 2013

ORAI1 calcium channel orchestrates skin homeostasis.

scientific article

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

scientific article

Orai1 is an essential pore subunit of the CRAC channel

scientific article

Orphans against autoimmunity

scientific article published on 01 August 2008

PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes

scientific article published on 7 August 2012

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation

scientific article published on 01 August 2019

Pore architecture of the ORAI1 store-operated calcium channel.

scientific article

Precancer Atlas to Drive Precision Prevention Trials.

scientific article

Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data

scientific article published in 2013

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

scientific article

RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation

scientific article

RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiation

scientific article

RNAi screening: tips and techniques

scientific article

Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL

scientific article

Regulation of T helper 17 differentiation by orphan nuclear receptors: it's not just ROR gamma t anymore

scientific article

Regulation of Th2 differentiation and Il4 locus accessibility.

scientific article

Regulation of gene expression in mast cells: micro-rNA expression and chromatin structural analysis of cytokine genes.

scientific article

Regulation of gene expression in peripheral T cells by Runx transcription factors

scientific article published on December 2009

Regulation of the germinal center response by microRNA-155

scientific article (publication date: 27 April 2007)

Regulatory T-cell gene expression: ChIP'ing away at Foxp3

scientific article published on 13 March 2007

Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development ⬇️

scholarly article

Role of NFAT proteins in IL13 gene transcription in mast cells

scientific article published on 30 June 2004

Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells

scientific article published on 22 June 2021

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

scientific article published on 12 January 2009

STIM1 gates the store-operated calcium channel ORAI1 in vitro

scientific article

STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity

scientific article

Scientific divagations: from signaling and transcription to chromatin changes in T cells

scientific article published on 10 November 2020

Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors

scientific article

Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules

scholarly article

Signaling to gene expression: calcium, calcineurin and NFAT

scientific article published on 01 January 2009

Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

scientific article published on 18 June 2007

Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis

scientific article

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

scientific article

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

scientific article published on 10 July 2018

SnapShot: effector and memory T cell differentiation

scientific article

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells

scientific article published on 14 February 2013

Store-operated calcium entry: Mechanisms and modulation

scientific article published on April 2015

Structural basis of HMCES interactions with DNA reveals multivalent substrate recognition: Supplementary files

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

scientific article published on 24 June 2019

Structural delineation of the calcineurin-NFAT interaction and its parallels to PP1 targeting interactions

scientific article published in October 2004

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

scientific article

Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor

scientific article published in February 2002

Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction

scientific article

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire.

scientific article published on 4 February 2013

T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia.

scientific article published on 21 August 2013

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

scientific article published on 10 June 2002

T-cell anergy

scientific article published on April 2004

TCR signal strength controls thymic differentiation of iNKT cell subsets

scientific article published in Nature Communications

TET Enzymes and 5hmC in Adaptive and Innate Immune Systems

TET Methylcytosine Oxidases in T Cell and B Cell Development and Function

scientific article published on 31 March 2017

TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures

scientific article published on 22 December 2021

TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the Aicda superenhancer

scientific article published on 01 April 2019

TET family dioxygenases and DNA demethylation in stem cells and cancers

scientific article

TET methylcytosine oxidases: new insights from a decade of research

scientific article published on 01 January 2020

TET proteins and 5-methylcytosine oxidation in hematological cancers

scientific article

TET proteins and 5-methylcytosine oxidation in the immune system

scientific article

TET proteins in natural and induced differentiation

scientific article

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells

scientific article published on 21 November 2016

TET-family dioxygenases and the TET activator Vitamin C in immune responses and cancer

scientific article published on 30 July 2020

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities

scientific article published on 4 May 2016

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities

scientific article published on 01 August 2017

TET2: epigenetic safeguard for HSC ⬇️

scientific article published on October 27, 2011

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

scientific article published on June 2013

TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells

scientific article

TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling

scientific journal article

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion

scientific article published on 31 May 2019

Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells

scientific article published on August 2008

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor

scientific article published on 24 April 2019

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

scientific journal article

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling

scientific article published on 05 December 2016

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

scientific journal article

Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility

scientific article

Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene

scientific article published in May 2002

The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine

scientific article

The NFAT1 transcription factor is a repressor of cyclin A2 gene expression

scientific article published on 21 May 2007

The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine

scientific article

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

scientific article (publication date: 26 January 2010)

The calcium/NFAT pathway: role in development and function of regulatory T cells

scientific article published on 16 April 2009

The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.

scientific article

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

scientific article published on 27 April 2015

The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection

scientific article published on 22 May 2017

The role of NFAT transcription factors in integrin-mediated carcinoma invasion

scientific article (publication date: July 2002)

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.

scientific article published on 10 February 2015

The transcription factor NFAT3 mediates neuronal survival

scientific article

The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress

scientific article

The transcriptional control of the perforin locus

scientific article published on May 2010

Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells

scientific article published on 31 December 2006

Transcriptional and epigenetic regulation of T cell hyporesponsiveness

scientific article

Transcriptional basis of lymphocyte tolerance.

scientific article

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance

scientific article

Transcriptional mechanisms underlying lymphocyte tolerance.

scientific article

Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT

scientific article published on 06 July 2007

Unusual Activity of a Chlamydomonas TET/JBP Family Enzyme

scientific article published on 22 August 2019

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

scientific article published on 30 June 2013

Whole-genome analysis of TET dioxygenase function in regulatory T cells

scientific article published on 21 July 2021

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity

scientific article published on 11 June 2018

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