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List of works by Roger Chammas

177Lu-DOTA-Bevacizumab: Radioimmunotherapy Agent for Melanoma

scientific article

18F-Fluoride PET/CT and 99mTc-MDP SPECT/CT can detect bone cancer at early stage in rodents

scientific article published on 17 May 2018

99mTechnetium- or Cy7-Labeled Fab(Tocilizumab) as Potential Multiple Myeloma Imaging Agents

scientific article published on 04 January 2021

A gene expression profile related to immune dampening in the tumor microenvironment is associated with poor prognosis in gastric adenocarcinoma

scientific article

A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production

scientific article

ADAM23 negatively modulates alpha(v)beta(3) integrin activation during metastasis.

scientific article

ATR-FTIR spectroscopy and CDKN1C gene expression in the prediction of lymph nodes metastases in papillary thyroid carcinoma

scientific article published on 24 October 2019

Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice.

scientific article published on 29 December 2010

Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death

scientific article published on 11 May 2017

Activation of the Wnt/beta-catenin signaling pathway during oral carcinogenesis process is not influenced by the absence of galectin-3 in mice

scientific article published on September 1, 2011

Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection

scientific article published on February 2007

Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell.

scientific article published on 25 March 2016

Anti-bevacizumab idiotype antibody vaccination is effective in inducing vascular endothelial growth factor-binding response, impairing tumor outgrowth

scientific article published on April 2016

Anti-tumor effect of endostatin mediated by retroviral gene transfer in mice bearing renal cell carcinoma

scientific article published on 18 May 2007

Anti-tumor therapy with macroencapsulated endostatin producer cells

scientific article

Antimicrobial peptide LL-37 participates in the transcriptional regulation of melanoma cells

scientific article

Antitumour efficacy of Piper tuberculatum and piplartine based on the hollow fiber assay.

scientific article published on 17 December 2014

Arg72Pro TP53 polymorphism and cancer susceptibility: a comprehensive meta-analysis of 302 case-control studies

scientific article published on 02 December 2010

Association between Polymorphisms in Inflammatory Response-Related Genes and the Susceptibility, Progression and Prognosis of the Diffuse Histological Subtype of Gastric Cancer

article

Association between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.

scientific article published on 11 June 2014

Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200.

scientific article published on 13 May 2015

Biological applications of a chimeric probe for the assessment of galectin-3 ligands.

scientific article published on 12 June 2007

Biosimilar Drugs: What Would Be a Reasonable Extrapolation?

scientific article published on 09 May 2017

Blocking FGF2 with a new specific monoclonal antibody impairs angiogenesis and experimental metastatic melanoma, suggesting a potential role in adjuvant settings

scientific article published on 3 December 2015

CCNA1 gene as a potential diagnostic marker in papillary thyroid cancer

scientific article published on 30 September 2020

Cardiac dysfunction in Pkd1-deficient mice with phenotype rescue by galectin-3 knockout

scientific article published on 27 July 2016

Cationic technetium and rhenium complexes with pendant carbohydrates

scientific article published on 28 January 2010

Cell internalization of 7-ketocholesterol-containing nanoemulsion through LDL receptor reduces melanoma growth in vitro and in vivo: a preliminary report

scientific article published on 4 February 2018

Changes in the proteomic profile during differentiation and maturation of human monocyte-derived dendritic cells stimulated with granulocyte macrophage colony stimulating factor/interleukin-4 and lipopolysaccharide

scientific article published on 01 April 2005

Characterization of LGALS3 (galectin-3) as a player in DNA damage response.

scientific article published on 22 April 2014

Characterization of the mechanisms underlying the crosstalk between galectins and notch in gastric cancer.

scientific article published on 4 April 2013

Clinical implication of 14-3-3 epsilon expression in gastric cancer.

scientific article published in April 2012

Cloning of a Thymic Stromal Cell Capable of Protecting Thymocytes from Apoptosis ⬇️

scientific article published on 01 April 1995

Comments to: Recurrence and complications of pterygium extended removal followed by extended conjunctival transplant for primary pterygia

scientific article published on 12 April 2016

Community-based network analyses reveal emerging connectivity patterns of protein-protein interactions in murine melanoma secretome

scientific article published on 01 December 2020

Coordinated expression of galectin-3 and galectin-3-binding sites in malignant mammary tumors: implications for tumor metastasis.

scientific article published on 29 June 2010

De novo galectin-3 expression influences the response of melanoma cells to isatin-Schiff base copper (II) complex-induced oxidative stimulus.

scientific article published on 27 August 2013

Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications.

scientific article published on 10 January 2014

Deregulated expression of annexin-A2 and galectin-3 is associated with metastasis in gastric cancer patients

scientific article

Differential development of oil granulomas induced by pristane injection in galectin-3 deficient mice

scientific article published on 14 November 2015

Differential proteomic analysis of noncardia gastric cancer from individuals of northern Brazil

scientific article

Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues

scientific article (publication date: 2014)

Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress

scientific article published on 06 March 2020

Emerging Autophagy Functions Shape the Tumor Microenvironment and Play a Role in Cancer Progression - Implications for Cancer Therapy

scientific article published on 25 November 2020

Emerging targets for combination therapy in melanomas

scientific article published on 05 October 2015

Emerging technologies in extracellular vesicle-based molecular diagnostics

scientific article published on 27 February 2014

Endostatin gene therapy enhances the efficacy of IL-2 in suppressing metastatic renal cell carcinoma in mice

scientific article published on 20 May 2010

Endostatin gene therapy stimulates upregulation of ICAM-1 and VCAM-1 in a metastatic renal cell carcinoma model ⬇️

scientific article published on June 15, 2012

Endostatin neoadjuvant gene therapy extends survival in an orthotopic metastatic mouse model of renal cell carcinoma

scientific article published on 21 December 2011

Endostatin- and interleukin-2-expressing retroviral bicistronic vector for gene therapy of metastatic renal cell carcinoma

scientific article published on March 2011

Ethnicity and cutaneous melanoma in the city of Sao Paulo, Brazil: a case-control study

scientific article (publication date: 2012)

European ancestry and polymorphisms in DNA repair genes modify the risk of melanoma: A case–control study in a high UV index region in Brazil

article

Evaluation of antimitotic and antiangiogenic effect of preoperative subconjunctival application of mitomycin C in primary pterygium: a randomized trial

scientific article published on 13 February 2019

Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

scientific article published on 11 May 2020

Exploring the distribution of genetic markers of pharmacogenomics relevance in Brazilian and Mexican populations

scientific article

Expression of APC protein during tongue malignant transformation in galectin-3-deficient mice challenged by the carcinogen 4-nitroquniline-n-oxide

scientific article published on 15 May 2014

Expression of PAFR as part of a prosurvival response to chemotherapy: a novel target for combination therapy in melanoma.

scientific article published on 18 April 2012

Expression of the selectable marker gene bsrm in BALB/MK cells induces apoptosis by overproduction of hydrogen peroxide

scientific article

Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy

scientific article published on 09 October 2019

Fibronectin expression is decreased in metastatic renal cell carcinoma following endostatin gene therapy.

scientific article published on 11 May 2012

Frequency of CDH1 germline variants and contribution of dietary habits in early age onset gastric cancer patients in Brazil

scientific article published on 20 March 2019

GD3 ganglioside-enriched extracellular vesicles stimulate melanocyte migration

scientific article published on 14 June 2018

Galectin-3 Determines Tumor Cell Adaptive Strategies in Stressed Tumor Microenvironments

scientific article

Galectin-3 Regulates the Expression of Tumor Glycosaminoglycans and Increases the Metastatic Potential of Breast Cancer

scientific article published on 17 December 2019

Galectin-3 as an immunohistochemical tool to distinguish pilocytic astrocytomas from diffuse astrocytomas, and glioblastomas from anaplastic oligodendrogliomas.

scientific article published in October 2004

Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages

scientific article published on 12 January 2014

Galectin-3 expression: a useful tool in the differential diagnosis of posterior fossa tumors in children.

scientific article

Galectin-3 modulates carbohydrate-dependent thymocyte interactions with the thymic microenvironment.

scientific article

Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection

scientific article published on 17 May 2013

Galectin-3 orchestrates the histology of mesentery and protects liver during lupus-like syndrome induced by pristane

scientific article published on 10 October 2019

Galectin-3 plays a modulatory role in the life span and activation of murine neutrophils during early Toxoplasma gondii infection.

scientific article published on 31 August 2009

Galectin-3 regulates peritoneal B1-cell differentiation into plasma cells

scientific article published on 20 August 2009

Galectin-3 sensitized melanoma cell lines to vemurafenib (PLX4032) induced cell death through prevention of autophagy

scientific article published on 16 February 2018

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

scientific article

Galectin-3: role in ocular allergy and potential as a predictive biomarker

scientific article published on 03 March 2018

Genotype and phenotype of balb/c mouse strain expressing h-2kb-tsa58- sv40 immortalizing oncogene.

scientific article published on 4 April 2013

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

scientific article published on 03 December 2016

Glycobiology of laminin-integrin interaction and the metastatic phenotype ⬇️

scientific article published on January 1, 1991

Glycosaminoglycan chains from alpha5beta1 integrin are involved in fibronectin-dependent cell migration.

scientific article published in August 2009

Guanosine promotes B16F10 melanoma cell differentiation through PKC-ERK 1/2 pathway

scientific article

Hedgehog signaling pathway mediates tongue tumorigenesis in wild-type mice but not in Gal3-deficient mice.

scientific article published on 16 September 2014

How Should Genetic Counseling for Ovarian Cancer Be Implemented in a Middle-Income Country? An Insight Based on the Brazilian Scenario

scientific article published on 01 September 2018

Hyperthermia increases the metastatic potential of murine melanoma ⬇️

scientific article published on 01 August 1997

ICESP, a research hub within a total cancer care center

scientific article published on 04 February 2019

Implications on glycobiological aspects of tumor hypoxia in breast ductal carcinoma in situ

scientific article published on 5 February 2013

Induction of sialic acid 9-O-acetylation by diverse gene products: Implications for the expression cloning of sialic acid O-acetyltransferases ⬇️

scientific article published on February 1, 1998

Inhibition of angiotensin II receptor 1 limits tumor-associated angiogenesis and attenuates growth of murine melanoma

scientific article published on 22 September 2009

Interaction between omega 3 PUFA and UVB radiation: Photoprotective effect in normal and tumoral murine melanocytes?

scientific article published on 03 October 2016

Interface of post-translational glycosylation and endoplasmic reticulum stress in melanoma: target to cancer cell sensitization to chemotherapeutic agents?

scientific article published on 4 April 2013

Lack of galectin-3 alters the balance of innate immune cytokines and confers resistance to Rhodococcus equi infection

scientific article published in October 2008

Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection.

scientific article

Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity

scientific article

Lack of galectin-3 modifies differentially Notch ligands in bone marrow and spleen stromal cells interfering with B cell differentiation

scientific article published on 22 February 2018

Lack of galectin-3 up-regulates IgA expression by peritoneal B1 lymphocytes during B cell differentiation

scientific article published on 24 May 2015

Laminin and fibronectin interactions with human melanoma cells: effect of glucocorticoids ⬇️

scientific article published on 01 January 1991

Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles

scientific article published on 28 July 2011

Managing oncology clinical trials during COVID-19 pandemic

scientific article published on 13 August 2020

Mannose receptor 1 expression does not determine the uptake of high-density mannose dendrimers by activated macrophages populations

scientific article published on 13 October 2020

Maturation of human iDCs by IL-18 plus PGE2, but not by each stimulus alone, induced migration toward CCL21 and the secretion of IL-12 and IFN-γ.

scientific article published on 11 May 2012

Melanocyte transformation associated with substrate adhesion impediment.

scientific article

Mesenchymal stem cells do not prevent antibody responses against human α-L-iduronidase when used to treat mucopolysaccharidosis type I.

scientific article

Metabolism under hypoxia in Tm1 murine melanoma cells is affected by the presence of galectin-3, a metabolomics approach

scientific article

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.

scientific article

Mitomycin C in pterygium treatment

scientific article

Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model

scientific article published on 14 April 2020

Molecular engineering of an EGFP/disintegrin-based integrin marker

scientific article published in August 2005

Mutational Profiling of Driver Tumor Suppressor and Oncogenic Genes in Brazilian Malignant Pleural Mesotheliomas

scientific article published on 05 May 2020

NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients

scientific article published on 05 April 2019

NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis

scientific article published on 12 January 2011

Neutrophils LL-37 migrate to the nucleus during overwhelming infection.

scientific article published on 4 June 2013

Novel primate-specific genes, RMEL 1, 2 and 3, with highly restricted expression in melanoma, assessed by new data mining tool

scientific article

O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer.

scientific article

Oncogenic effects of PAFR ligands produced in tumours upon chemotherapy and radiotherapy

scientific article published on 10 March 2017

PAF receptor and tumor growth

scientific article published on January 2014

Platelet activating factor receptor antagonists improve the efficacy of experimental chemo- and radiotherapy

scientific article published on 11 October 2018

Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy

scientific article

Polymorphisms in the p27kip-1 and prohibitin genes denote novel genes associated with melanoma risk in Brazil, a high ultraviolet index region

scientific article published in June 2013

Pre- and postnatal exposure of mice to concentrated urban PM2.5 decreases the number of alveoli and leads to altered lung function at an early stage of life

scientific article published on 05 June 2018

Preclinical anticancer effectiveness of a fraction from Casearia sylvestris and its component Casearin X: in vivo and ex vivo methods and microscopy examinations

scientific article published on 08 April 2016

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells.

scientific article published on February 2017

Prion protein ablation increases cellular aggregation and embolization contributing to mechanisms of metastasis

scientific article published in October 2009

Prohibitin expression deregulation in gastric cancer is associated with the 3' untranslated region 1630 C>T polymorphism and copy number variation

scientific article

Proteomic analysis of low- to high-grade astrocytomas reveals an alteration of the expression level of raf kinase inhibitor protein and nucleophosmin.

scientific article

Proteomic analysis of total cellular proteins of human neutrophils.

scientific article published on 31 August 2009

Proteomic and SAGE profiling of murine melanoma progression indicates the reduction of proteins responsible for ROS degradation.

scientific article published on March 2006

Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using Terminal Amine Isotopic Labeling of Substrates

scientific article published on 26 September 2018

Quantitative proteomic analysis and functional studies reveal that nucleophosmin is involved in cell death in glioblastoma cell line transfected with siRNA.

scientific article published on August 2012

RNA-Seq transcriptome analysis shows anti-tumor actions of melatonin in a breast cancer xenograft model

scientific article published in Scientific Reports

RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells

scientific article published on 01 February 2019

Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis

scientific article

Sialylation regulates galectin-3/ligand interplay during mammary tumour progression--a case of targeted uncloaking.

scientific article

Somatic mutations in early onset luminal breast cancer.

scientific article published on 27 April 2018

Stochastic model of contact inhibition and the proliferation of melanoma in situ

scientific article

Structural and inhibitory properties of a plant proteinase inhibitor containing the RGD motif.

scientific article published on 26 May 2006

Synthesis and Evaluation of [18F]FEtLos and [18F]AMBF3Los as Novel 18F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors

scientific article published on 18 April 2020

Synthesis of hydrophilic HYNIC-[1,2,4,5]tetrazine conjugates and their use in antibody pretargeting with 99mTc

scientific article published on 01 July 2018

Technetium glucose complexes as potential cancer imaging agents.

scientific article published on 14 August 2015

Technetium-99m- or Cy7-Labeled Rituximab as an Imaging Agent for Non-Hodgkin Lymphoma

scientific article published on 15 February 2017

The deficiency of galectin-3 in stromal cells leads to enhanced tumor growth and bone marrow metastasis

scientific article

The inactive form of glycogen synthase kinase-3β is associated with the development of carcinomas in galectin-3 wild-type mice, but not in galectin-3-deficient mice ⬇️

scientific article published on July 17, 2012

The involvement of the spleen during chronic phase of Schistosoma mansoni infection in galectin-3-/- mice

scientific article published on August 1, 2012

The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase

scientific article

The role of kinin receptors in cancer and therapeutic opportunities.

scientific article published on 11 December 2013

Tocilizumab labeling with 99mTechnetium via HYNIC as a molecular diagnostic agent for Multiple Myeloma.

scientific article

Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity

scientific article

Transient inflammatory response induced by apoptotic cells is an important mediator of melanoma cell engraftment and growth

scientific article

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner.

scientific article published on 28 April 2009

Tumors as complex organs: are cancers manageable through the modification of their microenvironment?

scientific article published on 4 April 2013

University participation in the production of molecular diagnostic tests for the novel coronavirus in Brazil: the response to health challenges

scientific article published on 26 June 2020

Unlike reactivity of mono- and binuclear imine-copper(II) complexes toward melanoma cells via a tyrosinase-dependent mechanism

scientific article published on 08 August 2019

Vascular endothelial growth factor as a biomarker for endostatin gene therapy

scientific article

XPC polymorphisms play a role in tissue-specific carcinogenesis: a meta-analysis.

scientific article published on 20 February 2008

[(99m)Tc(CO)(3)]-radiolabeled bevacizumab: in vitro and in vivo evaluation in a melanoma model.

scientific article published on 15 January 2013

p27 variant and corticotropinoma susceptibility: a genetic and in vitro study.

scientific article published on 28 April 2014

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