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List of works by Agostino Tafuri

A Population-Based Study on Myelodysplastic Syndromes in the Lazio Region (Italy), Medical Miscoding and 11-Year Mortality Follow-Up: the Gruppo Romano-Laziale Mielodisplasie Experience of Retrospective Multicentric Registry.

scientific article

A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol

scientific article published on 13 January 2005

A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review

Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells.

scientific article

Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol

scientific article published on 22 September 2005

Advances in targeting signal transduction pathways

scientific article

Aggressive lymphomas of the elderly: the DEVEC metronomic chemotherapy schedule fits the unfit.

scientific article published on 28 November 2017

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy

scientific article published on 21 February 2008

An increase in hemoglobin, platelets and white blood cells levels by iron chelation as single treatment in multitransfused patients with myelodysplastic syndromes: clinical evidences and possible biological mechanisms

scientific article

Apoptosis susceptibility and cell-cycle distribution in cells from myelodysplastic syndrome patients: modulatory in-vitro effects of G-CSF and interferon-alpha

scientific article published on 01 July 2004

Bcl-2 and mTOR as Effective Targets for Molecular Therapy of Acute Lymphoblastic Leukemia ⬇️

scholarly article

Biological Aspects of mTOR in Leukemia

scholarly article by Simone Mirabilii published in August 2018

Central nervous system immune reconstitution inflammatory syndrome after autologous stem cell transplantation

scientific article published on 08 May 2019

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia

scientific article published on 16 September 2015

Correlation between Charlson comorbidity index and outcome in patients with chronic phase chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors upfront

scientific article published on 9 February 2015

Deregulated expression of miR-29a-3p, miR-494-3p and miR-660-5p affects sensitivity to tyrosine kinase inhibitors in CML leukemic stem cells

scientific article published on 8 May 2017

Differential proteomic profile of leukemic CD34+ progenitor cells from chronic myeloid leukemia patients.

scientific article

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid) ⬇️

scientific article published on May 16, 1991

E2A-PBX1 fusion in adult acute lymphoblastic leukaemia: biological and clinical features

scientific article published on 01 February 2003

ERK1/2 phosphorylation is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia

scientific article

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine

scientific article published on 16 November 2012

Effects of IL-6 Variants in Multiple Myeloma: Growth Inhibition and Induction of Apoptosis in Primary Cells

scientific article published on 01 December 2002

Effects of mast cell growth factor on ara-c mediated acute myeloid leukemia cell killing ⬇️

scientific article published on 01 July 1993

Emerging MEK inhibitors.

scientific article published on June 2010

Emerging Raf inhibitors.

scientific article published on December 2009

Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin ⬇️

scientific article published on 20 October 2017

Erratum: The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia.

scientific article published on 5 February 2016

Functional and kinetic characterization of granulocyte colony-stimulating factor-primed CD34- human stem cells

scientific article published on 01 November 2003

GIMEMA AML1310 trial of risk-adapted, MRD-directed therapy for young adults with newly diagnosed acute myeloid leukemia

scientific article published on 08 August 2019

Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia

scientific article published on 8 June 2004

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

scientific article published on August 2009

Histopathological and molecular features of persistent polyclonal B-cell lymphocytosis (PPBL) with progressive splenomegaly

scientific article published on 26 December 2008

Hypoxia-inducible factor-1α(Pro-582-Ser) polymorphism prevents iron deprivation in healthy blood donors.

scientific article published on 08 August 2013

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein ⬇️

scientific article published on April 14, 1998

Increased death receptor resistance and FLIPshort expression in polycythemia vera erythroid precursor cells.

scientific article published on 29 December 2005

Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia

scientific article

Interleukin-11 induces proliferation of human T-cells and its activity is associated with downregulation of p27(kip1)

scientific article (publication date: April 2002)

Interleukin-9 in Human Myeloid Leukemia Cells ⬇️

scientific article published on August 1, 1997

Interleukin‐3 priming in acute myeloid leukaemia patients ⬇️

scientific article published on 01 September 1995

Isolated molecular relapse in FIP1L1-PDGFRalpha hypereosinophilic syndrome after discontinuation and single weekly dose of imatinib: need of quantitative molecular procedures to modulate imatinib dose

scientific article

MDR1 protein expression is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.

scientific article published in August 2002

MEK blockade converts AML differentiating response to retinoids into extensive apoptosis

scientific article published on 31 October 2006

Metabolic Reprogramming Promotes Myogenesis During Aging

scientific article published on 10 July 2019

Modulation Of The Glycolytic Metabolism In Acute Myeloid Leukemia Cells ⬇️

scholarly article

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib

scientific article published in December 2009

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response

scientific article published on September 2012

Novel Histone Deacetilase (HDAC) Inhibitors: In Vitro Effects on Leukemic Cells ⬇️

scholarly article

Overcoming resistance to molecularly targeted anticancer therapies: Rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies ⬇️

scientific article published on 7 May 2007

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression

scientific article

Preclinical Antileukemia Activity of Tramesan: A Newly Identified Bioactive Fungal Metabolite.

scientific article published on 15 November 2017

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia

scientific article published on 24 June 2008

Prolonged molecular remission in advanced acute promyelocytic leukaemia after treatment with gemtuzumab ozogamicin (MylotargTM CMA‐676) ⬇️

scientific article published on 01 October 2001

Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.

scientific article

RETRACTED ARTICLE: MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex ⬇️

scientific article published on November 8, 2011

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance

scientific article

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health

scientific article published on March 2011

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

scientific article

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

scientific article

Targeting Glycolysis and MAPK Pathway: A Combined Pre-Clinical Approach on Acute Myeloid Leukemia ⬇️

scholarly article

Targeting Metabolic Pathways for Leukemia Treatment ⬇️

scholarly article

Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells

scientific article published on 24 August 2017

Targeting the Akt, GSK-3, Bcl-2 axis in acute myeloid leukemia.

scientific article

Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.

scientific article

Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias.

scientific article published on 14 August 2015

The Activity of Differentiation Factors Induces Apoptosis in Polyomavirus Large T-Expressing Myoblasts ⬇️

scientific article published on June 1, 1998

The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera

scientific article published on 20 February 2017

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

scientific article

The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia

scientific article

The tissue inhibitor of metalloproteinases 1 increases the clonogenic efficiency of human hematopoietic progenitor cells through CD63/PI3K/Akt signaling

scientific article

Therapeutic potential of MEK inhibition in acute myelogenous leukemia: rationale for "vertical" and "lateral" combination strategies

scientific article

Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects

scientific article published on 22 August 2017

Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera.

scientific article published on 03 July 2013

Treatment of de novo acute myelogenous leukemia with recombinant granulocyte macrophage-colony-stimulating factor in combination with standard induction chemotherapy: effect of granulocyte macrophage-colony-stimulating factor on white blood cell cou ⬇️

scientific article published on 01 January 1992

Trisomy 13 in a patient with common acute lymphoblastic leukemia: description of a case and review of the literature

scientific article

mTOR Regulation of Metabolism in Hematologic Malignancies

scientific article published on 11 February 2020

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