List of works - Pamela E Knapp

5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat.

scientific article published on 13 January 2016

Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain

scientific article

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

scientific article

Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G

scientific article

Chronic HIV-1 Tat and HIV reduce Rbfox3/NeuN: evidence for sex-related effects

scientific article

Cross-talk between microglia and neurons regulates HIV latency

scientific article published on 30 December 2019

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

scientific article published on 20 April 2012

Differential expression of the alternatively spliced OPRM1 isoform μ-opioid receptor-1K in HIV-infected individuals

scientific article published on January 2014

Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interactions

scientific article published on 15 March 2019

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior

scientific article

Effects of chronic expression of the HIV-induced protein, transactivator of transcription, on circadian activity rhythms in mice, with or without morphine

scientific article published on 10 September 2008

Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes

scientific article

Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death

scientific article published on 17 November 2011

GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity

scientific article

HIV-1 Tat Inhibits Autotaxin Lysophospholipase D Activity and Modulates Oligodendrocyte Differentiation

scientific article published on 22 September 2016

HIV-1 Tat and opiate-induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP-1 and alternative chemokines

scientific article

HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice

scientific article published on 2 January 2017

HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation

scientific article

HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse

scientific article

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.

scientific article

Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine

scientific article

Ibudilast attenuates expression of behavioral sensitization to cocaine in male and female rats.

scientific article published on 22 June 2016

Impact of opiate-HIV-1 interactions on neurotoxic signaling

scientific article published on March 2006

Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors

scientific article

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

scientific article

Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

scientific article

Lateralized response of dynorphin a peptide levels after traumatic brain injury

scientific article

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

scientific article

Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain

scientific article published on 19 November 2011

Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice

scientific article published on October 2008

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice.

scientific article

Morphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neurites

scientific article (publication date: 2014)

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

scientific article

Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia

scientific article published on 18 November 2011

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development.

scientific article

Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.

scientific article published on January 2014

Opiate drug use and the pathophysiology of neuroAIDS.

scientific article

Pathobiology of dynorphins in trauma and disease

scientific article

Preferential vulnerability of astroglia and glial precursors to combined opioid and HIV-1 Tat exposure in vitro.

scientific article

Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability

scientific article published on 17 January 2017

Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

scientific article

Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence

scientific article

Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis

scientific article

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

scientific article published on 01 January 2021

Selective Vulnerability of Striatal D2 versus D1 Dopamine Receptor-Expressing Medium Spiny Neurons in HIV-1 Tat Transgenic Male Mice.

scientific article published on 4 May 2017

Short interfering RNA-induced gene silencing is transmitted between cells from the mammalian central nervous system

scientific article

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice.

scientific article published on 4 December 2012

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.

scientific article

List of works by Pamela E Knapp

5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat.

Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G

Chronic HIV-1 Tat and HIV reduce Rbfox3/NeuN: evidence for sex-related effects

Cross-talk between microglia and neurons regulates HIV latency

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

Differential expression of the alternatively spliced OPRM1 isoform μ-opioid receptor-1K in HIV-infected individuals

Effects of HIV-1 Tat on oligodendrocyte viability are mediated by CaMKIIβ-GSK3β interactions

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior

Effects of chronic expression of the HIV-induced protein, transactivator of transcription, on circadian activity rhythms in mice, with or without morphine

Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes

Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death

GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity

HIV-1 Tat Inhibits Autotaxin Lysophospholipase D Activity and Modulates Oligodendrocyte Differentiation

HIV-1 Tat and opiate-induced changes in astrocytes promote chemotaxis of microglia through the expression of MCP-1 and alternative chemokines

HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice

HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation

HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse

HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.

Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine

Ibudilast attenuates expression of behavioral sensitization to cocaine in male and female rats.

Impact of opiate-HIV-1 interactions on neurotoxic signaling

Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

Lateralized response of dynorphin a peptide levels after traumatic brain injury

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain

Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice.

Morphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neurites

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription

Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development.

Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.

Opiate drug use and the pathophysiology of neuroAIDS.

Pathobiology of dynorphins in trauma and disease

Preferential vulnerability of astroglia and glial precursors to combined opioid and HIV-1 Tat exposure in vitro.

Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability

Prodynorphin mutations cause the neurodegenerative disorder spinocerebellar ataxia type 23.

Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence

Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

Selective Vulnerability of Striatal D2 versus D1 Dopamine Receptor-Expressing Medium Spiny Neurons in HIV-1 Tat Transgenic Male Mice.

Short interfering RNA-induced gene silencing is transmitted between cells from the mammalian central nervous system

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice.

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.