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List of works by Frank E Uschner

"Tipping" extracellular matrix remodeling towards regression of liver fibrosis: novel concepts

scientific article

Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation.

scientific article published on 27 March 2019

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis.

scientific article published on 18 January 2018

Circulating microbiome in blood of different circulatory compartments

article

Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis

scientific article published on 12 June 2019

Combination of phosphodiesterase-5-inhibitors and beta blockers improves experimental portal hypertension and erectile dysfunction

scientific article published on 06 July 2020

Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis

scientific article published on 08 February 2019

Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation

scientific article published on 02 April 2020

Dynamic human liver proteome atlas reveals functional insights into disease pathways

scientific article published on 01 May 2022

Hemodynamic Effects of the Non-Peptidic Angiotensin-(1-7) Agonist AVE0991 in Liver Cirrhosis

scientific article published on 25 September 2015

Hepatic inflammasome activation as origin of Interleukin-1α and Interleukin-1β in liver cirrhosis

scientific article published on 21 October 2020

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.

scientific article

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis.

scientific article

Left Ventricular Longitudinal Contractility Predicts Acute-on-Chronic Liver Failure Development and Mortality After Transjugular Intrahepatic Portosystemic Shunt

article

Mouse and Rat Models of Induction of Hepatic Fibrosis and Assessment of Portal Hypertension.

scientific article

Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.

scientific article

Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury

scientific journal article

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis

scientific article published on 23 October 2019

Quantification of Liver Fibrosis at T1 and T2 Mapping with Extracellular Volume Fraction MRI: Preclinical Results

scientific article published on 26 June 2018

Quantification of liver fibrosis: extracellular volume fraction using an MRI bolus-only technique in a rat animal model

scientific article published on 29 May 2019

Quantitative liver MRI including extracellular volume fraction for non-invasive quantification of liver fibrosis: a prospective proof-of-concept study.

scientific article

Rationale for the use of statins in liver disease.

scientific article published on 9 March 2017

Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats

scientific article published on 19 February 2019

Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS

scientific article published on 03 July 2019

Safety of two different doses of simvastatin plus rifaximin in decompensated cirrhosis (LIVERHOPE-SAFETY): a randomised, double-blind, placebo-controlled, phase 2 trial

scientific article published on 10 October 2019

Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis

scientific article published on 11 August 2015

Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS

scientific article published on 10 September 2019

Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension.

scientific article published on 28 September 2015

Statins improve NASH via inhibition of RhoA and Ras.

scientific article published on 15 September 2016

TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor

scientific article published on 12 August 2019

The multikinase inhibitor regorafenib decreases angiogenesis and improves portal hypertension

scientific article published on 16 November 2018

The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats.

scientific article published on 19 June 2018

Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease

scientific article published in 2021

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