List of works - Ryoko Koga

A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

scientific article published on 8 September 2017

A clue to unprecedented strategy to HIV eradication: "Lock-in and apoptosis".

scientific article

A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.

scientific article

Anti-cancer activity of the cell membrane-permeable phytic acid prodrug

scientific article published on 04 September 2019

Antileukemic Activity of Twig Components of Caucasian Beech in Turkey

scientific article published on 25 October 2019

Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement

scientific article published on 10 September 2019

Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain

scientific article published on July 2014

Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.

scientific article

HSP70 induction by bleomycin metal core analogs

scientific article published on 31 January 2020

Introduction of H2C2-type zinc-binding residues into HIV-2 Vpr increases its expression level.

scientific article published on 19 December 2017

Minimum structural requirements for inhibitors of the zinc finger protein TRAF6

scientific article published on 27 June 2019

Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1.

scientific article published on 30 April 2015

Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia

scientific article published on 28 November 2018

New SIRT2 inhibitors: Histidine-based bleomycin spin-off

scientific article published on 02 March 2019

Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.

scientific article published on 29 July 2015

Poly-proline motif in HIV-2 Vpx is critical for its efficient translation.

scientific article published on 10 October 2013

Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature ⬇️

article

Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein

scientific article published on 04 August 2021

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents.

scientific article published on 20 October 2015

Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.

scientific article published on 12 November 2015

The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-Chronic Myelogenous Leukemia Activities

scientific article

Zinc-binding site of human immunodeficiency virus 2 Vpx prevents instability and dysfunction of the protein.

scientific article published on February 2017

Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G.

scientific article published on 18 July 2016

List of works by Ryoko Koga

A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

A clue to unprecedented strategy to HIV eradication: "Lock-in and apoptosis".

A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.

Anti-cancer activity of the cell membrane-permeable phytic acid prodrug

Antileukemic Activity of Twig Components of Caucasian Beech in Turkey

Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement

Design and synthesis of lipid-coupled inositol 1,2,3,4,5,6-hexakisphosphate derivatives exhibiting high-affinity binding for the HIV-1 MA domain

Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.

HSP70 induction by bleomycin metal core analogs

Introduction of H2C2-type zinc-binding residues into HIV-2 Vpr increases its expression level.

Minimum structural requirements for inhibitors of the zinc finger protein TRAF6

Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1.

Neuroprotective effects of a novel carnosine-hydrazide derivative on hippocampal CA1 damage after transient cerebral ischemia

New SIRT2 inhibitors: Histidine-based bleomycin spin-off

Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.

Poly-proline motif in HIV-2 Vpx is critical for its efficient translation.

Serial Femtosecond X-Ray Diffraction of HIV-1 Gag MA-IP6 Microcrystals at Ambient Temperature ⬇️

Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents.

Synthesis of the biotinylated anti-HIV compound BMMP and the target identification study.

The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-Chronic Myelogenous Leukemia Activities

Zinc-binding site of human immunodeficiency virus 2 Vpx prevents instability and dysfunction of the protein.

Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G.