List of works by Michael P Blundell

Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1

scientific article

Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells

scientific article

Frozen cord blood hematopoietic stem cells differentiate into higher numbers of functional natural killer cells in vitro than mobilized hematopoietic stem cells or freshly isolated cord blood hematopoietic stem cells

scientific article published on 29 January 2014

Generation of functional neutrophils from a mouse model of X-linked chronic granulomatous disorder using induced pluripotent stem cells

scientific article

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

scientific article

In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques

scientific article published on 12 August 2019

Integrin linked kinase (ILK) regulates podosome maturation and stability in dendritic cells.

scientific article published on 06 February 2014

Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors

scientific article

Long-Term Hematopoietic Engraftment of Congenic Amniotic Fluid Stem Cells After in Utero Intraperitoneal Transplantation to Immune Competent Mice.

scientific article

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane

scientific article published on 10 January 2013

Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency.

scientific article

Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model.

scientific article published on 14 October 2015

Natural killer cells differentiated in vitro from cord blood CD34+ cells are more advantageous for use as an immunotherapy than peripheral blood and cord blood natural killer cells

scientific article published on 17 April 2017

Phosphorylation of WASp is a key regulator of activity and stability in vivo

scientific article published on September 2009

Publisher Correction: In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques

scientific article published on 24 December 2019

Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation.

scientific article published on 26 February 2016

T cell gene therapy for perforin deficiency corrects cytotoxicity defects and prevents Haemophagocytic Lymphohistiocytosis manifestations.

scientific article published on 17 January 2018

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function

scientific article

Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells

scientific article

Trisomy 21 mid-trimester amniotic fluid induced pluripotent stem cells maintain genetic signatures during reprogramming: implications for disease modeling and cryobanking

scientific article published on 27 August 2014

Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach

scientific article

WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts.

scientific article