List of works - Aleksander Edelman

A new workflow for proteomic analysis of urinary exosomes and assessment in cystinuria patients

scientific article

A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.

scientific article

An unexpected effect of TNF-α on F508del-CFTR maturation and function

scientific article published on 10 July 2015

Analysis of nasal potential in murine cystic fibrosis models

scientific article

Antibodies for CFTR studies.

scientific article published in August 2004

Application of ion-selective microelectrodes to rat kidney proximal tubular cells [proceedings]

scientific article published on January 1, 1978

Association between Hsp90 and the ClC-2 chloride channel upregulates channel function

scientific article

Basic protocol for transepithelial nasal potential difference measurements

scientific article

Blue native/SDS-PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice.

scientific article

CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway.

scientific article

Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice

scientific article

Chloride distribution in the proximal convoluted tubule ofNecturus kidney ⬇️

scientific article published on 01 January 1981

Chloride transport in nasal ciliated cells of cystic fibrosis heterozygotes

scientific article

Cis variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules

scientific article published on 22 December 2017

Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients

scientific article

Cystic fibrosis enters the proteomics scene: new answers to old questions.

scientific article published on July 2006

Cytoskeleton and CFTR.

scientific article published on 28 March 2014

Determination of intracellular K+ activity in rat kidney proximal tubular cells ⬇️

scientific article published on December 15, 1978

Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain

scientific article

Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect

scientific article

Distribution of ClC-2 chloride channel in rat and human epithelial tissues

scientific article (publication date: April 2002)

Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells

scientific article

Evaluation of MRP1-5 gene expression in cystic fibrosis patients homozygous for the delta F508 mutation.

scientific article published on 20 August 2003

Expression of the human erythroid Rh glycoprotein (RhAG) enhances both NH3 and NH4+ transport in HeLa cells

scientific article

Farnesyltransferase inhibitor R115777 protects against vascular disease in uremic mice.

scientific article

Finding new drugs to enhance anion secretion in cystic fibrosis: Toward suitable systems for better drug screening. Report on the pre-conference meeting to the 12th ECFS Basic Science Conference, Albufeira, 25-28 March 2015.

scientific article

Functional interaction between CFTR and the sodium-phosphate co-transport type 2a in Xenopus laevis oocytes

scientific article

Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/deltaF508-CFTR to the plasma membrane

scientific article

High sensitivity identification of membrane proteins by MALDI TOF-MASS spectrometry using polystyrene beads

scientific article

Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.

scientific article published in August 2004

In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study

scientific article

Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice.

scientific article

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice.

scientific article

Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators

scientific article published in August 2004

Microelectrodes and their use to assess ion channel function

scientific article published in August 2004

NH3 is involved in the NH4+ transport induced by the functional expression of the human Rh C glycoprotein

scientific article

New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8.

scientific article

New lipidomic approaches in cystic fibrosis

scientific article

Normal function of the cystic fibrosis conductance regulator protein can be associated with homozygous (Delta)F508 mutation

scientific article published in November 2002

Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge

scientific article

Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.

scientific article

Proteomic analysis of nasal epithelial cells from cystic fibrosis patients

scientific article

Proteomics techniques for cystic fibrosis research.

scientific article published in August 2004

Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway

scientific article published on 08 August 2017

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis

scientific article published on 27 May 2016

Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network

scientific article

Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1.

scientific article

Sensitivity of mass spectrometry analysis depends on the shape of the filtration unit used for filter aided sample preparation (FASP).

scientific article published on 24 May 2016

The CF-CIRC study: a French collaborative study to assess the accuracy of cystic fibrosis diagnosis in neonatal screening

scientific article

The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity.

scientific article

The functioning of mammalian ClC-2 chloride channel in Saccharomyces cerevisiae cells requires an increased level of Kha1p

scientific article

The hsa-miR-125a/hsa-let-7e/hsa-miR-99b cluster is potentially implicated in Cystic Fibrosis pathogenesis

scientific article

The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation

scientific article

rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice

scientific article published on 28 October 2015

List of works by Aleksander Edelman

A new workflow for proteomic analysis of urinary exosomes and assessment in cystinuria patients

A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.

An unexpected effect of TNF-α on F508del-CFTR maturation and function

Analysis of nasal potential in murine cystic fibrosis models

Antibodies for CFTR studies.

Application of ion-selective microelectrodes to rat kidney proximal tubular cells [proceedings]

Association between Hsp90 and the ClC-2 chloride channel upregulates channel function

Basic protocol for transepithelial nasal potential difference measurements

Blue native/SDS-PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice.

CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway.

Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice

Chloride distribution in the proximal convoluted tubule ofNecturus kidney ⬇️

Chloride transport in nasal ciliated cells of cystic fibrosis heterozygotes

Cis variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules

Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients

Cystic fibrosis enters the proteomics scene: new answers to old questions.

Cytoskeleton and CFTR.

Determination of intracellular K+ activity in rat kidney proximal tubular cells ⬇️

Discovery of novel potent ΔF508-CFTR correctors that target the nucleotide binding domain

Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect

Distribution of ClC-2 chloride channel in rat and human epithelial tissues

Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells

Evaluation of MRP1-5 gene expression in cystic fibrosis patients homozygous for the delta F508 mutation.

Expression of the human erythroid Rh glycoprotein (RhAG) enhances both NH3 and NH4+ transport in HeLa cells

Farnesyltransferase inhibitor R115777 protects against vascular disease in uremic mice.

Finding new drugs to enhance anion secretion in cystic fibrosis: Toward suitable systems for better drug screening. Report on the pre-conference meeting to the 12th ECFS Basic Science Conference, Albufeira, 25-28 March 2015.

Functional interaction between CFTR and the sodium-phosphate co-transport type 2a in Xenopus laevis oocytes

Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/deltaF508-CFTR to the plasma membrane

High sensitivity identification of membrane proteins by MALDI TOF-MASS spectrometry using polystyrene beads

Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.

In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study

Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice.

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice.

Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators

Microelectrodes and their use to assess ion channel function

NH3 is involved in the NH4+ transport induced by the functional expression of the human Rh C glycoprotein

New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8.

New lipidomic approaches in cystic fibrosis

Normal function of the cystic fibrosis conductance regulator protein can be associated with homozygous (Delta)F508 mutation

Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge

Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients.

Proteomic analysis of nasal epithelial cells from cystic fibrosis patients

Proteomics techniques for cystic fibrosis research.

Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis

Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network

Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1.

Sensitivity of mass spectrometry analysis depends on the shape of the filtration unit used for filter aided sample preparation (FASP).

The CF-CIRC study: a French collaborative study to assess the accuracy of cystic fibrosis diagnosis in neonatal screening

The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity.

The functioning of mammalian ClC-2 chloride channel in Saccharomyces cerevisiae cells requires an increased level of Kha1p

The hsa-miR-125a/hsa-let-7e/hsa-miR-99b cluster is potentially implicated in Cystic Fibrosis pathogenesis

The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation

rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice