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List of works by Arjan van Caam

Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage.

scientific article

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.

scientific article

Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors

scientific article

IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3

scientific article published on 07 September 2018

IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes

scientific article

Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage

scientific article published on 21 January 2014

Interleukin-37 Protects Stem Cell-Based Cartilage Formation in an Inflammatory Osteoarthritis-Like Microenvironment

scientific article published on 28 March 2019

Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis.

scientific article

Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling.

scientific article

Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice

scientific article published on 19 December 2013

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

scientific article published on 18 December 2014

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?

scientific article published on 06 March 2020

TGFβ/BMP Signaling Pathway in Cartilage Homeostasis

scientific article published on 24 August 2019

TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity.

scientific article published on 31 May 2017

The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1.

scientific article

Transcription Factors in Cartilage Homeostasis and Osteoarthritis

scientific article published on 14 September 2020

Unraveling SSc Pathophysiology; The Myofibroblast

scientific article published on 13 November 2018

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