List of works - Hongtao Xu

2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia

scientific article published on 03 August 2018

A review of the total syntheses of triptolide

scientific article published on 22 August 2019

Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology

scientific article published on 20 January 2020

Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids.

scientific article published on 24 July 2017

Click chemistry-based synthesis and cytotoxic activity evaluation of 4α-triazole acetate podophyllotoxin derivatives

scientific article published on 28 November 2018

DNA-Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On-DNA Suzuki, Sonogashira, and Buchwald Reactions

scientific article published on 30 September 2019

Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi-triptolide.

scientific article published on 14 December 2013

Design, synthesis and structure-activity relationships studies on the D ring of the natural product triptolide

scientific article published on 11 December 2013

Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues.

scientific article published on 24 October 2014

Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides

scientific article

Functionality-Independent DNA Encoding of Complex Natural Products

scientific article published on 22 May 2019

Identification of a diverse synthetic abietane diterpenoid library and insight into the structure-activity relationships for antibacterial activity.

scientific article published on 9 November 2017

Identification of a diverse synthetic abietane diterpenoid library for anticancer activity.

scientific article

Iridium-catalyzed C-H amidation of s-tetrazines

scientific article published on 25 March 2020

LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo

scientific article published on 15 July 2017

MeCas12a, a Highly Sensitive and Specific System for COVID-19 Detection

scientific article published on 23 September 2020

Meeting organometallic chemistry with drug discovery: CH activation enabled discovery of a new ring system of 12H-Indazolo[2,1-a]cinnolin-12-ones with anti-proliferation activity

scientific article published on 23 December 2019

Ruthenium(ii)-catalyzed synthesis of indazolone-fused cinnolines via C-H coupling with diazo compounds

scientific article published on 01 October 2018

Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.

scientific article

Synthesis of N-Acyl Sulfamates from Fluorosulfonates and Potassium Trimethylsilyloxyl Imidates

scientific article published on 12 November 2019

Synthesis of Oridonin Derivatives via Mizoroki-Heck Reaction and Click Chemistry for Cytotoxic Activity

scientific article published on 01 January 2019

Triptolide-targeted delivery methods

scientific article published on 25 December 2018

Triptolide: Medicinal chemistry, chemical biology and clinical progress

scientific article published on 13 May 2019

List of works by Hongtao Xu

2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia

A review of the total syntheses of triptolide

Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology

Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids.

Click chemistry-based synthesis and cytotoxic activity evaluation of 4α-triazole acetate podophyllotoxin derivatives

DNA-Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On-DNA Suzuki, Sonogashira, and Buchwald Reactions

Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi-triptolide.

Design, synthesis and structure-activity relationships studies on the D ring of the natural product triptolide

Divergent total synthesis of triptolide, triptonide, tripdiolide, 16-hydroxytriptolide, and their analogues.

Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides

Functionality-Independent DNA Encoding of Complex Natural Products

Identification of a diverse synthetic abietane diterpenoid library and insight into the structure-activity relationships for antibacterial activity.

Identification of a diverse synthetic abietane diterpenoid library for anticancer activity.

Iridium-catalyzed C-H amidation of s-tetrazines

LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo

MeCas12a, a Highly Sensitive and Specific System for COVID-19 Detection

Meeting organometallic chemistry with drug discovery: CH activation enabled discovery of a new ring system of 12H-Indazolo[2,1-a]cinnolin-12-ones with anti-proliferation activity

Ruthenium(ii)-catalyzed synthesis of indazolone-fused cinnolines via C-H coupling with diazo compounds

Semisynthesis of triptolide analogues: effect of B-ring substituents on cytotoxic activities.

Synthesis of N-Acyl Sulfamates from Fluorosulfonates and Potassium Trimethylsilyloxyl Imidates

Synthesis of Oridonin Derivatives via Mizoroki-Heck Reaction and Click Chemistry for Cytotoxic Activity

Triptolide-targeted delivery methods

Triptolide: Medicinal chemistry, chemical biology and clinical progress