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List of works by Alaina J Ammit

A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro

scientific article published on 10 June 2016

Actions of platelet activating factor (PAF) on gametes and embryos: clinical aspects

scientific article published on January 1, 1992

Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.

scientific article published on 25 January 2016

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin

scientific article published on 18 May 2015

Corticosteroid-Induced MKP-1 Represses Pro-Inflammatory Cytokine Secretion by Enhancing Activity of Tristetraprolin (TTP) in ASM Cells.

scientific article published on 16 February 2016

Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1.

scientific article

Cyclooxygenase 2: its regulation, role and impact in airway inflammation.

scientific article published on 18 December 2015

Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect

scientific article published on 13 April 2017

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide

scientific article published on 27 May 2015

EP2 and EP4 receptor antagonists: Impact on cytokine production and β2 -adrenergic receptor desensitization in human airway smooth muscle

scientific article published on 07 December 2018

Effect of Sphingosine 1-Phosphate on Cyclo-Oxygenase-2 Expression, Prostaglandin E2 Secretion, and β2-Adrenergic Receptor Desensitization

scientific article published on 22 June 2015

Enhancing tristetraprolin activity reduces the severity of cigarette smoke-induced experimental chronic obstructive pulmonary disease

scientific article published on 28 October 2019

Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation.

scientific article published on 28 February 2017

IL-17A increases TNF-α-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on β2 -adrenergic receptor desensitization.

scientific article

Inhibitors of Phosphodiesterase 4, but Not Phosphodiesterase 3, Increase β2-Agonist-Induced Expression of Antiinflammatory Mitogen-Activated Protein Kinase Phosphatase 1 in Airway Smooth Muscle Cells.

scientific article published in May 2015

Long-acting β2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (MKP-1) in airway smooth muscle cells.

scientific article

MAPK p38 regulates inflammatory gene expression via tristetraprolin: Doing good by stealth.

scientific article published on 8 November 2017

Metabolic and developmental responses of preimplantation embryos to platelet activating factor (PAF)

scientific article published on January 1, 1992

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

scientific article published on 25 July 2019

Platelet-activating factor (PAF) receptor antagonists inhibit arachidonic acid induced platelet aggregation in rabbit whole blood ⬇️

scientific article published on 01 December 1991

Production of platelet-activating factor by the pre-implantation sheep embryo ⬇️

scientific article published on November 1, 1991

Prostaglandin E2 induces expression of MAPK phosphatase 1 (MKP-1) in airway smooth muscle cells

scientific article

Prostaglandin E2, but not cAMP nor β2-agonists, induce tristetraprolin (TTP) in human airway smooth muscle cells

scientific article published on 09 March 2019

Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

scientific article published on 17 October 2019

Regulation of ATP binding cassette transporter A1 (ABCA1) expression: cholesterol-dependent and - independent signaling pathways with relevance to inflammatory lung disease

scientific article published on 25 September 2020

Regulation of pulmonary inflammation by mesenchymal cells

scientific article published on 20 March 2014

Repression of breast cancer cell growth by proteasome inhibitors in vitro: impact of mitogen-activated protein kinase phosphatase 1

scientific article

Repurposing of statins via inhalation to treat lung inflammatory conditions

scientific article published on 08 June 2018

Roflumilast N-Oxide in Combination with Formoterol Enhances the Antiinflammatory Effect of Dexamethasone in Airway Smooth Muscle Cells.

scientific article published on 20 December 2016

Role and regulation of MKP-1 in airway inflammation.

scientific article published on 10 August 2017

Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses

scientific article published on 26 June 2019

Role of dynamin in elongated cell migration in a 3D matrix.

scientific article

Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury

scientific article

Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease.

scientific article published on 30 January 2018

Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids

scientific article

Structural heterogeneity of platelet-activating factor produced by murine preimplantation embryos ⬇️

scientific article published on 01 July 1992

Studies of the Nature of the Binding by Albumin of Platelet-activating Factor Released from Cells ⬇️

scientific article published on July 25, 1997

TLR2 activation causes tachyphylaxis to β2 -agonists in vitro and ex vivo: modelling bacterial exacerbation.

scientific article published on 3 July 2014

TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.

scientific article published on 28 July 2016

Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice

scientific article

Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1.

scientific article

The NLRP3 inflammasome: role in airway inflammation.

scientific article published on February 2014

The effect of inhibitors of platelet aggregation on the metabolism of platelet-activating factor (PAF) in washed rabbit platelets ⬇️

scientific article published on 01 December 1991

The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation.

scientific article published on October 2013

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells.

scientific article published on 4 August 2014

The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells

scientific article

Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator.

scientific article published on 17 November 2015

Tristetraprolin and its role in regulation of airway inflammation

scientific article

para-Sulfonatocalix[4]arene and polyamidoamine dendrimer nanocomplexes as delivery vehicles for a novel platinum anticancer agent.

scientific article

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