Search filters

List of works by Emmanouil Fokas

A comparison of radiotherapy with radiotherapy plus surgery for brain metastases from urinary bladder cancer: analysis of 62 patients

scientific article

A phase-I trial of pre-operative, margin intensive, stereotactic body radiation therapy for pancreatic cancer: the 'SPARC' trial protocol ⬇️

scientific article

A spatial and functional interaction of a heterotetramer Survivin-DNA-PKcs complex in DNA damage response

scientific article published on 06 January 2021

A treatment planning comparison of four target volume contouring guidelines for locally advanced pancreatic cancer radiotherapy

scientific article published in May 2013

ACTR-63. TREATMENT AND SURVIVAL OF PATIENTS WITH LOWER GRADE GLIOMA ACCORDING TO THE 2007 AND THE 2016 WHO CLASSIFICATION: A RETROSPECTIVE ANALYSIS OF 423 PATIENTS

ARCII: A phase II trial of the HIV protease inhibitor Nelfinavir in combination with chemoradiation for locally advanced inoperable pancreatic cancer

scientific article published on 23 April 2016

Acute organ toxicity correlates with better clinical outcome after chemoradiotherapy in patients with anal carcinoma

scientific article published on 14 May 2020

Advantage of robotic needle placement on a prostate model in HDR brachytherapy ⬇️

scientific article published on May 17, 2011

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse

scientific article

Anal squamous cell carcinoma - State of the art management and future perspectives

scientific article published on 22 February 2018

Association of Plane of Total Mesorectal Excision With Prognosis of Rectal Cancer: Secondary Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial

scientific article published on 15 August 2018

Association of Polo-Like Kinase 3 and PhosphoT273 Caspase 8 Levels With Disease-Related Outcomes Among Cervical Squamous Cell Carcinoma Patients Treated With Chemoradiation and Brachytherapy

scientific article published on 14 August 2019

Association of Sex With Toxic Effects, Treatment Adherence, and Oncologic Outcomes in the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trials of Rectal Cancer

scientific article published on 05 December 2019

Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer: A Post Hoc Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial

scientific article published on 09 July 2020

Atlas-based semiautomatic target volume definition (CTV) for head-and-neck tumors

scientific article published on 12 July 2010

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.

scientific article published on 25 May 2017

Biology of brain metastases and novel targeted therapies: Time to translate the research ⬇️

scientific article published on November 7, 2012

Brain Metastases in Breast Cancer: Analysis of the Role of HER2 Status and Treatment in the Outcome of 94 Patients ⬇️

scientific article published on November 1, 2012

C-Reactive Protein-to-Albumin Ratio as Prognostic Marker for Anal Squamous Cell Carcinoma Treated With Chemoradiotherapy

scientific article published on 08 November 2019

CD8+ tumour-infiltrating lymphocytes in relation to HPV status and clinical outcome in patients with head and neck cancer after postoperative chemoradiotherapy: A multicentre study of the German cancer consortium radiation oncology group (DKTK-ROG).

scientific article

Can clinicopathological parameters predict for lymph node metastases in ypT0-2 rectal carcinoma? Results of the CAO/ARO/AIO-94 and CAO/ARO/AIO-04 phase 3 trials

scientific article published on 18 June 2018

Combined p16 and p53 expression in cervical cancer of unknown primary and other prognostic parameters : A single-center analysis

scientific article published on 31 January 2017

Comparing dose-volume histogram and radiobiological endpoints for ranking intensity-modulated arc therapy and 3D-radiotherapy treatment plans for locally-advanced pancreatic cancer.

scientific article published on 19 August 2013

Comparison of investigator-delineated gross tumor volumes and quality assurance in pancreatic cancer: Analysis of the pretrial benchmark case for the SCALOP trial

scientific article published on 29 August 2015

Comparison of investigator-delineated gross tumour volumes and quality assurance in pancreatic cancer: Analysis of the on-trial cases for the SCALOP trial

scientific article published on 3 August 2016

Complete response after chemoradiotherapy for rectal cancer: what is the reasonable approach?

scientific article published on 28 December 2017

Contrast enhancing spots as a new pattern of late onset pseudoprogression in glioma patients

scientific article published on 02 January 2019

Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer

scientific article

Definitive, Preoperative, and Palliative Radiation Therapy of Esophageal Cancer

scientific article

Delta-like ligand 4-notch blockade and tumor radiation response

scientific article

Downstage migration after neoadjuvant chemoradiotherapy for rectal cancer: the reverse of the Will Rogers phenomenon?

scientific article published on 21 January 2015

Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature ⬇️

scientific article published on November 22, 2011

ERGO2: A prospective randomized trial of calorie restricted ketogenic diet and fasting in addition to re-irradiation for malignant glioma

scientific article published on 30 June 2020

EphA2 blockade enhances the anti-endothelial effect of radiation and inhibits irradiated tumor cell-induced migration of endothelial cells.

scientific article

Erratum to: Combined p16 and p53 expression in cervical cancer of unknown primary and other prognostic parameters

scientific article published on 01 August 2017

Expression of the Wnt antagonist DKK3 is frequently suppressed in sporadic epithelial ovarian cancer

scientific article

Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1

scientific article published on 16 May 2020

Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer

scientific article published in August 2017

Genetic alterations after carbon ion irradiation in human lung adenocarcinoma cells.

scientific article published on January 2011

Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncolo

scientific article published on 13 December 2017

Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy

scientific article published on 6 February 2017

Human papillomavirus DNA load and p16INK4a expression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy

scientific article published on 27 May 2014

Hypofractionated stereotactic reirradiation of recurrent glioblastomas : a beneficial treatment option after high-dose radiotherapy?

scientific article published on 16 April 2009

In reply to Weiss et al

scientific article published on 01 December 2014

Inclusion of oxaliplatin in the multimodal treatment of locally advanced rectal cancer

scientific article

Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients.

scientific article

Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

scientific article

Ion beam radiobiology and cancer: time to update ourselves

scientific article published on 12 August 2009

Irradiation-dependent effects on tumor perfusion and endogenous and exogenous hypoxia markers in an A549 xenograft model

scientific article

Leukocytosis and neutrophilia as independent prognostic immunological biomarkers for clinical outcome in the CAO/ARO/AIO-04 randomized phase 3 rectal cancer trial

scientific article published on 02 April 2019

Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer.

scientific article

Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

scientific article published on 21 October 2016

Maintenance of Energy Homeostasis during Calorically Restricted Ketogenic Diet and Fasting-MR-Spectroscopic Insights from the ERGO2 Trial

scientific article published on 27 November 2020

Management of anal cancer patients - a pattern of care analysis in German-speaking countries

scientific article published on 25 May 2020

Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma

Metastasis: the seed and soil theory gains identity

scientific article published on December 2007

Modulation of radiation sensitivity and antitumor immunity by viral pathogenic factors: Implications for radio-immunotherapy

scientific article published on 31 December 2018

Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab

scientific article

Multidisciplinary Treatment of Brain Metastases Derived From Colorectal Cancer Incorporating Stereotactic Radiosurgery: Analysis of 78 Patients ⬇️

scientific article published on April 22, 2011

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity ⬇️

scientific article published on March 27, 2012

Neutrophils promote hepatic metastasis growth through fibroblast growth factor 2-dependent angiogenesis in mice

scientific article published on 30 January 2017

Nivolumab for pretreated metastatic anal cancer : Immune checkpoint blockade is also advised in combination with radiochemotherapy

scientific article published in February 2018

Nuclear NF-κB Expression Correlates With Outcome Among Patients With Head and Neck Squamous Cell Carcinoma Treated With Primary Chemoradiation Therapy ⬇️

scientific article published on May 9, 2013

Optimal fractionation regimen, and time between radiotherapy and operation in rectal cancer : The multicenter, randomized Stockholm III trial

scientific article published on 11 July 2017

Outcome measures in multimodal rectal cancer trials

scientific article published on 01 May 2020

PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy

scientific article published on 8 December 2016

Pancreatic ductal adenocarcinoma: From genetics to biology to radiobiology to oncoimmunology and all the way back to the clinic

scientific article published on 07 December 2014

Performance Status Restriction in Phase III Cancer Clinical Trials

scientific article published on 01 October 2020

Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer.

scientific article

Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy

scientific article published on 23 July 2016

Preoperative chemoradiation therapy with capecitabine/oxaliplatin and cetuximab in rectal cancer: long-term results of a prospective phase 1/2 study

scientific article published on 24 October 2013

Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

scientific article published on 6 November 2017

Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

scientific article published on 14 September 2016

Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.

scientific article published on 14 June 2016

Progression-free survival is a suboptimal predictor for overall survival among metastatic solid tumour clinical trials

scientific article published on 20 July 2020

Quality of life after stereotactic radiotherapy for meningioma: a prospective non-randomized study ⬇️

scientific article published on February 28, 2013

Quality of life in rectal cancer patients with or without oxaliplatin in the randomised CAO/ARO/AIO-04 phase 3 trial

scientific article published on 28 December 2020

RADIANCE - Radiochemotherapy with or without Durvalumab in the treatment of anal squamous cell carcinoma: A randomized multicenter phase II trial

scientific article published on 01 May 2020

Radiotherapy for brain metastases from renal cell cancer: should whole-brain radiotherapy be added to stereotactic radiosurgery?: analysis of 88 patients.

scientific article

Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12

scientific article published on 31 May 2019

Re-irradiation of recurrent gliomas: pooled analysis and validation of an established prognostic score-report of the Radiation Oncology Group (ROG) of the German Cancer Consortium (DKTK).

scientific article published on 23 March 2018

Rectal cancer: Neoadjuvant chemoradiotherapy

scientific article published on 28 June 2016

Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia

scientific article published on 13 March 2014

Reply to A. Abdalla et al

scientific article published on 09 October 2019

Sarcopenia Is Associated With Hematologic Toxicity During Chemoradiotherapy in Patients With Anal Carcinoma

scientific article published on 12 August 2020

Sex-Based Disparities Among Cancer Clinical Trial Participants

scientific article published on 01 February 2020

Siah1 proteins enhance radiosensitivity of human breast cancer cells ⬇️

scientific article published on August 3, 2010

Situation of young radiation oncologists, medical physicists and radiation biologists in German-speaking countries : Results from a web-based survey of the Young DEGRO working group.

scientific article published on 24 June 2016

Stereotactic radiation therapy for benign meningioma: long-term outcome in 318 patients

scientific article published on 18 April 2014

Stereotactic radiosurgery and fractionated stereotactic radiotherapy: comparison of efficacy and toxicity in 260 patients with brain metastases ⬇️

scientific article published on April 15, 2012

Stereotactic radiosurgery of cerebral arteriovenous malformations: long-term follow-up in 164 patients of a single institution ⬇️

scientific article published on May 28, 2013

Stereotactic radiotherapy of benign meningioma in the elderly: clinical outcome and toxicity in 121 patients

scientific article published on 08 May 2014

Targeted Therapies and Immune-Checkpoint Inhibition in Head and Neck Squamous Cell Carcinoma: Where Do We Stand Today and Where to Go?

scientific article published on 3 April 2019

Targeted agents in GI radiotherapy: Clinical efficacy and side effects

scientific article published on 13 May 2016

Targeting ATR in DNA damage response and cancer therapeutics.

scientific article published on 11 April 2013

Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis

scientific article

The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

scientific article published on 08 May 2017

The Role of Radiotherapy in the Multimodal Management of Esophageal Cancer ⬇️

scientific article published on June 17, 2013

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia.

scientific article published on 25 July 2016

The immune microenvironment and HPV in anal cancer: Rationale to complement chemoradiation with immunotherapy.

scientific article

The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies ⬇️

scientific article published on December 1, 2012

The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy

scientific article

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma

scientific article published on 26 December 2015

The results of the LAP07 trial should not be misunderstood as the end of chemoradiotherapy in pancreatic cancer

scientific article published on 18 October 2016

Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer

scientific article published in December 2017

Tumor Regression Grading After Preoperative Chemoradiotherapy for Locally Advanced Rectal Carcinoma Revisited: Updated Results of the CAO/ARO/AIO-94 Trial

article by Emmanouil Fokas et al published 20 May 2014 in Journal of Clinical Oncology

Tumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer

scientific article published on January 2014

[How long should we wait upon completion of chemoradiotherapy before assessment of tumor response in anal cancer?]

scientific article published on 01 July 2017

[Influence of treatment compliance on the success of chemoradiotherapy for anal carcinoma]

scientific article published on 19 June 2020

miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD).

scientific article

Paulina is supported by:

About Paulina

Help