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List of works by Elizabeth O. Hexner

A common, under-recognized cause of elevated serum erythropoietin

scientific article published on 19 August 2014

A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis

scientific article

A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia.

scientific article published on 20 October 2009

A photo-distributed papulopustular eruption and multiple squamous cell carcinomas in a patient on ruxolitinib

scientific article published on 22 October 2019

A prospective evaluation of pegylated interferon alfa-2a therapy in patients with polycythemia vera and essential thrombocythemia with a prior splanchnic vein thrombosis

scientific article published on 30 July 2019

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2

scientific article

AUF-1 and YB-1 are critical determinants of β-globin mRNA expression in erythroid cells.

scientific article published on December 2011

AUF-1 and YB-1 independently regulate β-globin mRNA in developing erythroid cells through interactions with poly(A)-binding protein

scientific article

Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition

scientific article published on 24 December 2014

Allogeneic transplantation for myelofibrosis: for whom, when, and what are the true benefits?

scientific article published on March 2014

Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease

scientific article published in March 2005

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802

article

An early-biomarker algorithm predicts lethal graft-versus-host disease and survival

scientific article published on 23 August 2018

An early-biomarker algorithm predicts lethal graft-versus-host disease and survival.

scientific article published on 09 February 2017

Bilateral facial paralysis in a non-Hodgkin lymphoma during remission period: a rare but an important condition to be investigated

scientific article published on 07 June 2016

Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin

scientific article published on 01 December 2020

Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease ⬇️

scientific article published on July 12, 2012

CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.

scientific article published on 13 June 2017

CD4+ T cells generated de novo from donor hemopoietic stem cells mediate the evolution from acute to chronic graft-versus-host disease

scientific article published on 01 September 2007

CD44: expanding the tool

scientific article published on 01 November 2018

CRISPR-engineered T cells in patients with refractory cancer

scientific article published on 07 February 2020

Cellular adoptive immunotherapy after autologous and allogeneic hematopoietic stem cell transplantation

scientific article published on January 2009

Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease

scientific article published on 19 February 2013

Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies

scientific article published on 02 August 2013

Dendritic cell-activated CD44hiCD8+ T cells are defective in mediating acute graft-versus-host disease but retain graft-versus-leukemia activity

scientific article published on 5 February 2004

Disease risk and GVHD biomarkers can stratify patients for risk of relapse and nonrelapse mortality post hematopoietic cell transplant

scientific article published on 04 February 2020

Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning

scientific article

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis

scientific article (publication date: 30 June 2016)

Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I.

scientific article

Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I.

scientific article

Extended CCR5 Blockade for Graft-Versus-Host Disease Prophylaxis Improves Outcomes of Reduced Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial

scientific article published on 10 October 2018

Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice

scientific article

Fluorescent in situ hybridization of a skin biopsy: an adjunctive tool to support a diagnosis of graft-versus-host disease

scientific article published on 01 June 2011

Germline duplication of ATG2B and GSKIP genes is not required for the familial myeloid malignancy syndrome associated with the duplication of chromosome 14q32

scientific article published on 07 August 2018

Graft-versus-host disease depletes plasmacytoid dendritic cell progenitors to impair tolerance induction

scientific article published on 22 October 2020

High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning

scientific article published on 8 June 2015

High-dose corticosteroids with or without etanercept for the treatment of idiopathic pneumonia syndrome after allo-SCT ⬇️

scientific article published on February 6, 2012

Higher Donor Apheresis Blood Volumes are Associated with a Reduction in Relapse Risk and Improved Survival in Reduced Intensity Allogeneic Transplants with Unrelated Donors.

scientific article published on 2 February 2018

Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation

scientific article published on 21 December 2015

Hodgkin lymphoma patients have an increased incidence of idiopathic acquired aplastic anemia

scientific article published on 05 April 2019

Host-reactive CD8+ memory stem cells in graft-versus-host disease

scientific article

Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice

scientific article

Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease

scientific article

Inflammatory cytokine inhibition with combination daclizumab and infliximab for steroid-refractory acute GVHD.

scientific article

Infusion of CD3/CD28 costimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment

scientific article published on 8 February 2016

Intrinsic Resistance to JAK2 Inhibition in Myelofibrosis ⬇️

scientific article published on February 5, 2013

JAK2 V617F-positive acute myeloid leukaemia (AML): a comparison between de novo AML and secondary AML transformed from an underlying myeloproliferative neoplasm. A study from the Bone Marrow Pathology Group

scientific article published on 16 May 2018

JAK2 V617F: implications for thrombosis in myeloproliferative diseases

scientific article published on September 2007

Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors

scientific article

Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

scientific article

Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia

scientific article published on 16 April 2020

Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial

scientific article

MAGIC biomarkers predict long term outcomes for steroid-resistant acute GVHD.

scientific article published on 15 March 2018

Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways ⬇️

scientific article published on November 11, 2012

Molecular-based classification of acute myeloid leukemia and its role in directing rational therapy: personalized medicine for profoundly promiscuous proliferations

scientific article published on December 2012

Multicenter analysis of the use of transjugular intrahepatic portosystemic shunt for management of MPN-associated portal hypertension

scientific article published on 24 May 2017

Myelofibrosis 2012: it’s complicated ⬇️

scientific article published on June 1, 2012

Myelofibrosis patients can develop extramedullary complications including renal amyloidosis and sclerosing hematopoietic tumor while otherwise meeting traditional measures of ruxolitinib response

scientific article published on 19 September 2018

Myeloid/Lymphoid Neoplasms with Eosinophilia and TK Fusion Genes, Version 3.2021, NCCN Clinical Practice Guidelines in Oncology

scientific article published on 01 September 2020

Myeloproliferative neoplasms with concurrent BCR-ABL1 translocation and JAK2 V617F mutation: a multi-institutional study from the bone marrow pathology group.

scientific article published on 12 January 2018

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

scientific article

Open-label study of oral CEP-701 (lestaurtinib) in patients with polycythaemia vera or essential thrombocythaemia with JAK2-V617F mutation

scientific article

Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia

scientific article published on 09 December 2019

Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients

scientific article published on 01 May 2019

Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells

scientific article published on 16 January 2007

Pediatric chronic myeloid leukemia with inv(3)(q21q26.2) and T lymphoblastic transformation: a case report

scientific article published on 22 July 2016

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

scientific article published on 01 October 2019

Persistent Mixed Donor Chimerism following Double Umbilical Cord Transplantation in a Patient with T-Cell Prolymphocytic Leukemia

scientific article published on 11 September 2019

Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase

scientific article published on 01 October 2020

Phase 3 clinical trial of steroids/mycophenolate mofetil vs steroids/placebo as therapy for acute GVHD: BMT CTN 0802.

scientific article

Phase I dose escalation study of lestaurtinib in patients with myelofibrosis

scientific article published on 07 January 2015

Phase II trial of Lestaurtinib, a JAK2 inhibitor, in patients with myelofibrosis

scientific article published on 22 January 2019

Pilot Study of Prophylactic Ex Vivo Costimulated Donor Leukocyte Infusion After Reduced-Intensity Conditioned Allogeneic Stem Cell Transplantation ⬇️

scientific article published on April 28, 2013

Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): Consensus on terminology by the international working group for myelofibrosis resear

scientific article published on 8 January 2007

Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium

scientific article published on 28 August 2012

RNA interference for treating haematological malignancies

scientific article

Receipt of maintenance therapy is most predictive of survival in older acute lymphoblastic leukemia patients treated with intensive induction chemotherapy regimens ⬇️

scientific article published on June 5, 2013

Risk of Invasive Fungal Infections in Patients with High-Risk MDS and AML Receiving Hypomethylating Agents

scientific article published on 03 April 2020

Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms

Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition.

scientific article published on 2 April 2018

Targeted signal transduction therapies in myeloid malignancies ⬇️

scientific article published on November 1, 2010

The MAGIC algorithm probability is a validated response biomarker of treatment of acute graft-versus-host disease

scientific article published on 01 December 2019

The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation.

scientific article published on 28 December 2015

The cell cycle regulator CDC25A is a target for JAK2V617F oncogene.

scientific article published on 7 November 2011

The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis

scientific article published on 11 March 2013

The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies

scientific article published on September 2016

The role of T cells in hematopoietic stem cell engraftment

scientific article

Thiamine-responsive megaloblastic anemia: identification of novel compound heterozygotes and mutation update

scientific article

Time to unrelated donor leukocyte infusion is longer, but incidence of GVHD and overall survival are similar for recipients of unrelated DLI compared to matched sibling DLI.

scientific article published on 28 January 2016

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract

scientific article published on 24 May 2018

Trisomy 8 in an allogeneic stem cell transplant recipient representative of a donor-derived constitutional abnormality

scientific article

Umbilical cord blood xenografts in immunodeficient mice reveal that T cells enhance hematopoietic engraftment beyond overcoming immune barriers by stimulating stem cell differentiation

scientific article

Unrelated donors are associated with improved relapse-free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity allogeneic stem cell transplantation

scientific article published on 20 May 2016

Venous thromboembolism following pegaspargase in adults receiving antithrombin supplementation

scientific article published on 01 June 2020

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