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List of works by Deborah J. Lenschow

6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro

scientific article

6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities

scientific article published on 02 July 2020

A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses

scientific article

Anti-tumor necrosis factor therapy in patients with difficult to treat Takayasu arteritis

scientific article published in July 2004

Antiviral Properties of ISG15 ⬇️

scientific article published on September 28, 2010

Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis

scientific article

Chikungunya virus-induced autophagy delays caspase-dependent cell death

scientific article

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen

scientific article

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

scientific article published on 27 July 2012

Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease

scientific article published on 21 December 2020

Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection

scientific article published on 10 February 2012

Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA

scientific article published on 29 August 2019

Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation

scientific article published on 12 December 2019

Emerging roles for immunomodulatory functions of free ISG15.

scientific article published on 06 September 2013

Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription

scientific article

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus

scientific article

ISG15 deficiency and increased viral resistance in humans but not mice

scientific article

ISG15 functions as an interferon-mediated antiviral effector early in the murine norovirus life cycle

scientific article

ISG15 in antiviral immunity and beyond

scientific article published on 01 July 2018

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation

scientific article

Identification of a candidate therapeutic autophagy-inducing peptide

scientific journal article

Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo

scientific article

Increased Cerebral Protein ISGylation after Focal Ischemia is Neuroprotective ⬇️

scientific article published on August 17, 2011

Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus

scientific article

Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death

scientific article published on 01 February 2019

Lessons learned from Chikungunya in the Americas

scientific article published on 23 January 2018

Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection

scientific article published on 12 November 2008

Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins

scientific article published on 01 June 2020

Nitrosylation of ISG15 prevents the disulfide bond-mediated dimerization of ISG15 and contributes to effective ISGylation

scientific article published on 7 July 2008

Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice

scientific article

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

scientific article

Pillars article: CTLA-4 can function as a negative regulator of T cell activation. Immunity. 1994. 1: 405-413

scientific article published on October 1, 2011

Polymyalgia rheumatica/temporal arteritis: recent advances

scientific article

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells

scientific article

Replication-competent fluorescent-expressing influenza B virus

scientific article

Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor

scientific article published on 30 October 2013

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

scientific article

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein

scientific article

The antiviral activities of ISG15.

scientific article published on 03 October 2013

The impact of ISGylation during Mycobacterium tuberculosis infection in mice.

scientific article published on 10 January 2017

The microbial metabolite desaminotyrosine protects from influenza through type I interferon.

scientific article

Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis

scientific article

Type I interferons link viral infection to enhanced epithelial turnover and repair.

scientific article

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