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List of works by Peter M Glazer

2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.

scientific article

A cell-penetrating antibody inhibits human RAD51 via direct binding.

scientific article published on 28 September 2017

Altered Repair of Targeted Psoralen Photoadducts in the Context of an Oligonucleotide-mediated Triple Helix ⬇️

scientific article published on September 22, 1995

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.

scientific article published on 12 September 2017

Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51

scientific article published on 01 May 2019

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance

scientific article published in January 2008

Cooperation between oncogenic Ras and wild-type p53 stimulates STAT non-cell autonomously to promote tumor radioresistance

scientific article published on 19 March 2021

DNA-dependent targeting of cell nuclei by a lupus autoantibody.

scientific article published on 9 July 2015

Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells ⬇️

scientific article published on May 1, 2003

Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment Radiation Damage to Cancer Cells

scientific article published on 20 November 2018

Functional and physical interaction between the mismatch repair and FA-BRCA pathways ⬇️

scientific article published on August 24, 2011

High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation

scientific article published on 28 February 2019

Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1

scientific article published on 22 June 2018

Hypoxia induces resistance to EGFR inhibitors in lung cancer cells via upregulation of FGFR1 and the MAPK pathway

scientific article published on 01 September 2020

Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter ⬇️

scientific article published on June 13, 2011

Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.

scientific article published on 31 March 2014

In utero nanoparticle delivery for site-specific genome editing.

scientific article

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

scientific article (publication date: 26 October 2016)

Induction of p53 in mouse cells decreases mutagenesis by UV radiation ⬇️

scientific article published on October 1, 1995

Interplay between DNA repair and inflammation, and the link to cancer

scientific article

Ku80-targeted pH-sensitive peptide-PNA conjugates are tumor selective and sensitize cancer cells to ionizing radiation

scientific article published on 25 February 2020

LKB1 preserves genome integrity by stimulating BRCA1 expression

scientific article

Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease

scientific article published on 12 September 2018

Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and potent activity toward DNA double-strand break repair-deficient cell lines

scientific article published on 22 April 2015

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

scientific article

MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU

scientific article

Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung.

scientific article

Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment

scientific article published on May 2015

Mutagenesis Mediated by Triple Helix–Forming Oligonucleotides Conjugated to Psoralen: Effects of Linker Arm Length and Sequence Context ⬇️

scientific article published on March 1, 1998

Mutagenesis induced by the tumor microenvironment ⬇️

scientific article published on May 25, 1998

Nanoparticles Deliver Triplex-forming PNAs for Site-specific Genomic Recombination in CD34+ Human Hematopoietic Progenitors ⬇️

scientific article published on September 21, 2010

Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

scientific article published on 27 April 2015

Nanotechnology for delivery of peptide nucleic acids (PNAs)

scientific article

New translational possibilities for microenvironmental modulation of radiosensitivity ⬇️

scientific article published on 08 July 2011

Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells.

scientific article published on 2 May 2017

Oncometabolites suppress DNA repair by disrupting local chromatin signalling

scientific article published on 03 June 2020

PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF

scientific article published on 08 May 2018

Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma

scientific article published on 08 October 2018

Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

scientific article published on 08 February 2020

Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing.

scientific article published on 11 March 2018

Peptide nucleic acid-mediated recombination for targeted genomic repair and modification.

scientific article published on January 2014

Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells ⬇️

scientific article published on February 17, 1998

Polymer delivery systems for site-specific genome editing ⬇️

scientific article published on May 18, 2011

Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors ⬇️

scientific article published on December 20, 2011

Processing of Targeted Psoralen Cross-Links in Xenopus Oocytes ⬇️

scientific article published on November 1, 1997

Radiation sensitivity and sensitization in melanoma.

scientific article published on 12 August 2013

Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage ⬇️

scientific article published on August 29, 2011

Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1

scientific article

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition

scientific article

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice

scientific article

Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity in VHL-deficient human renal cell carcinoma.

scientific article published on 19 December 2017

Targeted Disruption of the CCR5 Gene in Human Hematopoietic Stem Cells Stimulated by Peptide Nucleic Acids ⬇️

scientific article published on September 23, 2011

Targeting cancer with a lupus autoantibody

scientific article published on October 2012

The Tumor Microenvironment and DNA Repair ⬇️

scientific article published on October 1, 2010

The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.

scientific article

The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.

scientific article published on 6 March 2018

Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.

scientific article published on 22 January 2013

Triplex-mediated genome targeting and editing.

scientific article published on January 2014

Tumor suppressor p53 stole the AKT in hypoxia

scientific article published on 11 May 2015

YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.

scientific article published on 26 June 2015

miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair

scientific article

microRNAs in cancer cell response to ionizing radiation.

scientific article published on 04 February 2014

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