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List of works by Emmanuelle Passegué

Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice

scientific article

Adult stem cells and regenerative medicine-a symposium report

scientific article published on 26 October 2019

Autophagy maintains the metabolism and function of young and old stem cells.

scientific article published on March 2017

Born to survive: autophagy in hematopoietic stem cell maintenance.

scientific article published on 10 June 2013

Cancer biology: A game of subversion

scientific article published in Nature

Cancer biology: a game of subversion.

scientific article published in August 2006

Cancer stem cells are everywhere

scientific article published on 01 January 2009

Cell cycle regulation in hematopoietic stem cells

scientific article

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

scientific article published on 25 April 2016

Chronic versus acute myelogenous leukemia: a question of self-renewal

scientific article published in December 2004

DNA-damage response in tissue-specific and cancer stem cells

scientific article published on January 2011

Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia

scientific article published on 01 March 2020

Dynamic expression of the Robo ligand Slit2 in bone marrow cell populations.

scientific article published on 15 February 2012

Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis

scientific article published on 15 May 2020

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

scientific article published on 15 October 2006

Evidence that the Pim1 kinase gene is a direct target of HOXA9

scientific journal article

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

scientific article published on 6 February 2013

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

scientific article (publication date: 26 January 2007)

Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis

scientific article published on 20 July 2015

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions.

scientific article published on 18 June 2015

Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

scientific article

HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

scientific article published on March 2008

Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family

scientific article published on October 2008

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

scientific article

Hematopoietic stem cells, leukemic stem cells and chronic myelogenous leukemia.

scientific article

Hypophyseal cells model systems: the "GH" rat tumor-derived cell lines as a tool for the study of gene expression

scientific article published on July 1, 1992

IFN-alpha wakes up sleeping hematopoietic stem cells.

scientific article published on June 2009

IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development

scientific article

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia

scientific article

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia

scientific article published on 01 October 2018

Initially disadvantaged, TEL-AML1 cells expand and initiate leukemia in response to irradiation and cooperating mutations.

scientific article published on 16 January 2013

Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils

scientific article

JEM women in STEM: Unique journeys with a common purpose

scientific article published on 01 March 2020

JunB can substitute for Jun in mouse development and cell proliferation

scientific journal article

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells

scientific article published in October 2004

JunB inhibits proliferation and transformation in B-lymphoid cells.

scientific article

JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.

scientific article published in April 2009

K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

scientific article published on 27 December 2006

Leukemic stem cells: where do they come from?

scientific article published on January 2005

Linking HSCs to their youth.

scientific article published in August 2013

Losing Sense of Self and Surroundings: Hematopoietic Stem Cell Aging and Leukemic Transformation

scientific article published on 17 May 2019

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging.

scientific article published on 15 March 2018

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

scientific article published on 01 February 2003

Mechanisms controlling hematopoietic stem cell functions during normal hematopoiesis and hematological malignancies

scientific article published on 15 March 2011

Metabolic makeover for HSCs

scientific article published in January 2013

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.

scientific article

MicroRNA-126 regulates HOXA9 by binding to the homeobox

scientific article

Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells

scientific article

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

scientific article published on 29 March 2017

Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.

scientific article published on 11 July 2013

New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors

scientific article

Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration

scientific article published on 27 January 2020

Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? ⬇️

scientific article published on September 22, 2003

Normal and leukemic stem cell niches: insights and therapeutic opportunities.

scientific article

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

scientific article published in October 2010

Oncogenic Kras initiates leukemia in hematopoietic stem cells

scientific article (publication date: 17 March 2009)

PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia

scientific article published on 21 September 2010

Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis

scientific article

Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

scientific article

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

scientific article published on 03 February 2014

Regulating quiescence: new insights into hematopoietic stem cell biology

scientific article

Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality

scientific article

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

scientific article published on 30 July 2014

Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.

scientific article published on 22 September 2013

Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression

scientific article published on 01 April 2022

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

scientific article

Stem cells assessed

scientific article published on 8 June 2012

Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing

scientific article published in 2023

Surviving change: the metabolic journey of hematopoietic stem cells.

scientific article published on 24 April 2014

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.

scholarly article

TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration

scientific article published on 20 June 2019

The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007.

scientific article published on 25 October 2007

The aged hematopoietic system promotes hippocampal-dependent cognitive decline

scientific article published on 21 July 2020

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.

scientific article published on 19 December 2016

The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

scientific article

The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells

scientific article published in April 2008

The transcription factor Srf regulates hematopoietic stem cell adhesion

scientific journal article

Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.

scientific article published on 18 June 2015

Validation of MdmX as a therapeutic target for reactivating p53 in tumors

scientific article

fester, A candidate allorecognition receptor from a primitive chordate

scientific article published in July 2006

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