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List of works by Mark Thursz

1171. Impact on Mortality, Length of Stay, and Antibiotic Use in Allogenic and Autologous Stem Cell Transplant Patients Colonized With Carbapenemase-Producing Enterobacteriaceae

3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection.

scientific article published on 14 February 2018

A clinician's guide to the cost and health benefits of hepatitis C cure assessed from the individual patient perspective.

scientific article

ACG Clinical Guideline for Alcoholic Liver Disease: The MELD Threshold for Corticosteroid Treatment has Yet to be Established

scientific article published on 01 January 2019

Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example.

scientific article

Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase

scientific article published on 01 February 2015

Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study

scientific article published on 15 January 2019

Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study

scientific article published on 15 January 2019

Antibiotic-Associated Disruption of Microbiota Composition and Function in Cirrhosis Is Restored by Fecal Transplant

scientific article published on 01 September 2018

Anticoagulation in chronic liver disease

scientific article published on 11 January 2017

Application of Prognostic Scores in The Stopah Trial: Discriminant Function is no Longer the Optimal Scoring System in Alcoholic Hepatitis.

scientific article published on 21 November 2017

Assessment and Management of Infection in Alcoholic Hepatitis

scientific article published on 01 August 2019

Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

scientific article published on 20 November 2019

Baseline neutrophil-to-lymphocyte ratio predicts response to corticosteroids and is associated with infection and renal dysfunction in alcoholic hepatitis

scientific article published on 17 July 2019

Basis of HBV persistence and new treatment options

scientific article

Battlefield against hepatitis B infection and HCC in Africa.

scientific article

Blockade of PD1 and TIM3 restores innate and adaptive immunity in patients with acute alcoholic hepatitis.

scientific article published on 2 December 2014

Breaking Down Barriers to Care in Hepatitis C Virus Infection

scientific article

CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure.

scientific article published on 7 June 2017

CD8+T cells from patients with cirrhosis display a phenotype that may contribute to cirrhosis-associated immune dysfunction

scientific article published on 31 October 2019

Can antiviral therapy of chronic hepatitis B prevent the development of hepatocellular carcinoma? ⬇️

scientific article published on April 20, 2011

Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*.

scientific article

Clinical utility of HCV core antigen detection and quantification using serum samples and dried blood spots in people who inject drugs in Dar-es-Salaam, Tanzania.

scientific article published on September 2017

Commentary: how long does one need to fast before a Fibroscan examination? Authors' reply

scientific article published on 01 March 2014

Community-based screening and treatment for chronic hepatitis B in sub-Saharan Africa - Authors' reply.

scientific article

Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis.

scientific article

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials

scientific article published on 05 May 2018

Cost-effectiveness of community-based screening and treatment for chronic hepatitis B in The Gambia: an economic modelling analysis

scientific article published on August 2016

Could targeting secretory leukocyte protease inhibitor be an effective therapeutic option to prevent infections in acute liver failure?

scientific article published on 01 January 2014

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

scientific article published on 16 July 2019

Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase

scientific article

Derivation and validation of a cardiovascular risk score for prediction of major acute cardiovascular events in non-alcoholic fatty liver disease; the importance of an elevated mean platelet volume

scientific article published on 05 March 2019

Detection of Rare Allelic Variants of the Interferon-α2Gene in Human Genomic DNA ⬇️

scientific article published on 01 May 1995

Detection of allele specific differences in IFNL3 (IL28B) mRNA expression

scientific article

Development of a simple score based on HBeAg and ALT for selecting patients for HBV treatment in Africa

scientific article published on 01 July 2018

Diagnostic accuracy of the gamma-glutamyl transpeptidase to platelet ratio (GPR) using transient elastography as a reference

scientific article published on 26 February 2016

Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.

scientific article published on 25 August 2014

Early diagnosis and treatment: the goal of hepatitis C screening

scientific article published on 24 February 2015

Economic evaluations of HBV testing and treatment strategies and applicability to low and middle-income countries.

scientific article published in November 2017

Editorial: importance of an elevated mean platelet volume for prediction of major adverse cardiovascular events in non-alcoholic fatty liver disease - authors' reply

scientific article published on 01 April 2019

Endpoints and patient stratification in clinical trials for alcoholic hepatitis

scientific article published on 01 February 2019

Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: A randomized clinical trial

scientific article published on 17 July 2017

Food intake increases liver stiffness measurements and hampers reliable values in patients with chronic hepatitis B and healthy controls: the PROLIFICA experience in The Gambia.

scientific article published on 5 December 2013

Functional imaging of hepatocellular carcinoma

scientific article published on 29 March 2016

Functional microbiomics: Evaluation of gut microbiota-bile acid metabolism interactions in health and disease

article

Genetic susceptibility in chronic viral hepatitis ⬇️

scientific article published on November 1, 2001

Get Active ⬇️

scientific article published on 01 January 2012

Global metabolic changes induced by plant-derived pyrrolizidine alkaloids following a human poisoning outbreak and in a mouse model

article

Granulocyte colony-stimulating factor as a novel adjunct to improve hepatitis B vaccination ⬇️

scientific article published on March 27, 2010

Hepatitis B Core-related Antigen: An Alternative to Hepatitis B Virus DNA to Assess Treatment Eligibility in Africa

scientific article published on 01 March 2020

Hepatitis B testing and treatment in HIV patients in The Gambia-Compliance with international guidelines and clinical outcomes

scientific article

Hepatitis C disease burden and strategies to manage the burden (Guest Editors Mark Thursz, Gregory Dore and John Ward).

scientific article published on May 2014

Hepatitis C, a global issue: access to care and new therapeutic and preventive approaches in resource-constrained areas

scientific article published on February 2014

Hepatitis D virus antigen in HBsAg positive chronic liver disease in Nigeria

scientific article published on June 1, 1998

Hepatitis E virus infection and acute-on-chronic liver failure in West Africa: a case-control study from The Gambia

scientific article

Heterozygote advantage for HLA class-II type in hepatitis B virus infection ⬇️

scientific article published on September 1, 1997

High prevalence and poor linkage to care of transfusion-transmitted infections among blood donors in Dar-es-Salaam, Tanzania

scientific article published on 27 February 2019

High-Throughput, Machine Learning-Based Quantification of Steatosis, Inflammation, Ballooning, and Fibrosis in Biopsies From Patients With Nonalcoholic Fatty Liver Disease

scientific article published on 27 December 2019

Hirmi Valley liver disease: a disease associated with exposure to pyrrolizidine alkaloids and DDT.

scientific article published on 20 August 2013

Homozygosity for rs738409:G in PNPLA3 is associated with increased mortality following an episode of severe alcoholic hepatitis.

scientific article published in February 2017

Host Factors in Chronic Viral Hepatitis ⬇️

scientific article published on January 1, 1997

Host genetic factors influencing the outcome of hepatitis ⬇️

scientific article published on July 1, 1997

Identification of mutations in circulating cell-free tumour DNA as a biomarker in hepatocellular carcinoma

scientific article published on 04 June 2019

Implementation of an in-house quantitative real-time polymerase chain reaction method for Hepatitis B virus quantification in West African countries.

scientific article

In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA.

scientific article published on 30 December 2016

In the shadow of HIV/AIDS: Forgotten diseases in sub-Saharan Africa: Global health issues and funding agency responsibilities ⬇️

scientific article published on August 16, 2012

In-field evaluation of Xpert® HCV viral load Fingerstick assay in people who inject drugs in Tanzania

scientific article published on 15 December 2019

Increased Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure

scientific article published on 28 March 2017

Influence of IFNL3.rs12979860 and IFNL4.ss469415590 polymorphism on clearance of hepatitis C virus infection among Egyptians

scientific article published on 12 March 2015

Innovative strategies for the elimination of viral hepatitis at a national level: A country case series

scientific article published on 04 September 2019

Intensive Enteral Nutrition in Alcoholic Hepatitis: More Food for Thought.

scientific article published on 25 February 2016

Interleukin 28A.rs12980602 and interleukin 28B.rs8103142 genotypes could be protective against HCV infection among Egyptians

scientific article published on 01 February 2019

Jaundiced after a party ⬇️

scientific article published on June 29, 2011

Letter: depression and the use of anti-depressants in patients with chronic liver disease or liver transplantation - authors' reply.

scientific article published in May 2015

Letter: role of mean platelet volume levels in the prediction of major acute cardiovascular events in patients with non-alcoholic fatty liver disease-authors' reply

scientific article published on 01 November 2019

Liver transplantation for alcoholic hepatitis: Being consistent about where to set the bar

scientific article published on 01 June 2018

MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure.

scientific article published on 27 April 2017

Micro-elimination - A path to global elimination of hepatitis C.

scientific article

Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection

scientific article published on 11 February 2019

Microbiome manipulation with faecal microbiome transplantation as a therapeutic strategy in Clostridium difficile infection

scientific article

Modulation of monocyte/macrophage function: a therapeutic strategy in the treatment of acute liver failure.

scientific article published on 02 April 2014

Monocyte-macrophage activation is associated with nonalcoholic fatty liver disease and liver fibrosis in HIV monoinfection independently of the gut microbiome and bacterial translocation

scientific article published on 01 April 2019

Mother-to-child transmission of hepatitis B in sub-Saharan Africa.

scientific article published in January 2016

Mother-to-child transmission of hepatitis B virus in sub-Saharan Africa: time to act.

scientific article published on July 2015

Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice

scientific article (publication date: 2013)

Next-generation sequencing sheds light on the natural history of hepatitis C infection in patients who fail treatment

scientific article published on 30 July 2014

Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces.

scientific article

Overview of hepatitis B prevalence, prevention, and management in the Pacific Islands and Territories

scientific article

PROLIFICA: a story of West African clinical and research collaborations to target hepatitis B-related hepatocellular carcinoma in West Africa

scientific article published on 22 June 2015

Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.

scientific article published on 3 December 2014

People who survive an episode of severe alcoholic hepatitis should be advised to maintain total abstinence from alcohol.

scientific article

Piloting a multidisciplinary clinic for the management of non-alcoholic fatty liver disease: initial 5-year experience.

scientific article published on 23 May 2013

Prednisolone or Pentoxifylline for Alcoholic Hepatitis

scientific article published on 01 July 2015

Prevalence and risk factors of nonalcoholic fatty liver disease in HIV-monoinfection

scientific article published on 10 April 2017

Prevalent acute-on-chronic liver failure and response to corticosteroids in alcoholic hepatitis

scientific article published on 24 August 2018

Prevention of Liver Fibrosis and Cancer in Africa: The PROLIFICA project--a collaborative study of hepatitis B-related liver disease in West Africa.

scientific article

Prevention of materno-foetal transmission of hepatitis B in sub-Saharan Africa: the evidence, current practice and future challenges.

scientific article published on June 2014

Proteomic and metabonomic biomarkers for hepatocellular carcinoma: a comprehensive review

scientific article published on 31 March 2015

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

scientific article published on 26 December 2019

Reply to: "The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort".

scientific article published on 11 December 2017

Reply to: "The long-term prognosis of alcoholic hepatitis is poor and independent of disease severity for patients surviving an acute episode"

scientific article published on 08 March 2018

Reply: To PMID 24797101.

scientific article

Requirements for global elimination of hepatitis B: a modelling study

scientific article published on 13 September 2016

Review article: depression and the use of antidepressants in patients with chronic liver disease or liver transplantation

scientific article published on September 2014

Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study.

scientific article published on 20 April 2017

Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model

scientific article published on 29 January 2019

Screening and treatment of hepatitis B virus to prevent liver cancer in Africa

scientific article published on 20 April 2015

Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

article

Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis

scientific article published on 01 March 2020

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

scientific article published on 17 February 2021

Sofosbuvir-based treatment regimens: real life results of 14 409 chronic HCV genotype 4 patients in Egypt.

scientific article

Strengthening vaccine confidence during the COVID-19 pandemic: A new opportunity for global hepatitis B virus elimination

scientific article published on 24 July 2020

Systematic review with meta-analysis: high mortality in patients with non-severe alcoholic hepatitis

scientific article published on 23 June 2019

The Role of Liver Fibrosis Assessment in the Management of Patients with Chronic Hepatitis B Infection: Lessons Learned from a Single Centre Experience ⬇️

scientific article published on October 30, 2011

The allele 4 of neck region liver-lymph node-specific ICAM-3-grabbing integrin variant is associated with spontaneous clearance of hepatitis C virus and decrease of viral loads.

scientific article published on 6 November 2013

The clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2 × 2 factorial randomised controlled trial

scientific article

The cost impact of outreach testing and treatment for hepatitis C in an urban Drug Treatment Unit

scientific article

The diversity and management of chronic hepatitis B virus infections in the United Kingdom: a wake-up call.

scientific article

The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease

scientific article published on 16 September 2018

The future of therapy for alcoholic hepatitis - Beyond corticosteroids

scientific article published on 18 February 2019

The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa

scientific article published on 24 June 2015

The hepatitis C cascade of care in people who inject drugs in Dar es Salaam, Tanzania

scientific article published on 30 July 2018

The importance of baseline viral load when assessing relative efficacy in treatment-naïve HBeAg-positive chronic hepatitis B: a systematic review and network meta-analysis

scientific article

The prevalence and burden of symptoms in patients with chronic liver diseases in The Gambia, West Africa

scientific article published on 5 September 2014

The role of hypercoagulability in liver fibrogenesis ⬇️

scientific article published on May 14, 2011

The state of hepatitis B and C in the Mediterranean and Balkan countries: report from a summit conference.

scientific article published in August 2013

Thrombin and factor Xa link the coagulation system with liver fibrosis.

scientific article published on 8 May 2018

Time matters: Point of care screening and streamlined linkage to care dramatically improves hepatitis C treatment uptake in prisoners in England

scientific article published on 20 November 2019

Trace element deficiency is highly prevalent and associated with infection and mortality in patients with alcoholic hepatitis

scientific article published on 23 June 2020

Treatment for hepatitis B.

scientific article published on 05 January 2010

Treatment of Severe Alcoholic Hepatitis.

scientific article published on 3 March 2016

Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites

scientific article published on 01 November 2020

Universal screening of acute medical admissions for excess alcohol consumption: What's the misuse?

scientific article published on 27 July 2017

Validation of rapid point-of-care (POC) tests for detection of hepatitis B surface antigen in field and laboratory settings in the Gambia, Western Africa.

scientific article

Viral hepatitis in resource-limited countries and access to antiviral therapies: current and future challenges.

scientific article published on April 2013

Viral hepatitis: Scaling up HCV treatment in resource-limited countries.

scientific article published on 24 February 2015

Viral hepatitis: “E” is for equitable elimination

scientific article published on 23 July 2018

Welcome to the new, all electronic Journal of Viral Hepatitis.

scientific article published in January 2015

[Prevention of liver fibrosis and liver cancer linked to hepatitis B virus in Africa: the Prolifica study]

scientific article published on 22 May 2019

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