List of works - Nicole F Liachko

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

scientific article published on 01 December 2019

Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice

scientific article published on 23 November 2020

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.

scientific article

Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau

scientific article published on 30 September 2019

Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity

scientific article

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

scientific article published on 13 December 2019

Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance

scientific article

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

scientific article published on 15 February 2019

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

scientific article

Phenotypic Suppression of ALS/FTD-Associated Neurodegeneration Highlights Mechanisms of Dysfunction

scientific article published on 01 October 2019

Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy ⬇️

scientific article published on December 1, 2010

Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis

scientific article

Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

scientific article published on 07 June 2019

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing.

scientific article published on 17 January 2018

TDP-43/FUS in motor neuron disease: Complexity and challenges.

scientific article

Tau tubulin kinases in proteinopathy

scientific article published on 22 May 2019

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.

scientific article published on 29 July 2016

The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43

scientific article (publication date: December 2014)

List of works by Nicole F Liachko

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.

Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau

Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

Phenotypic Suppression of ALS/FTD-Associated Neurodegeneration Highlights Mechanisms of Dysfunction

Phosphorylation Promotes Neurotoxicity in a Caenorhabditis elegans Model of TDP-43 Proteinopathy ⬇️

Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis

Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing.

TDP-43/FUS in motor neuron disease: Complexity and challenges.

Tau tubulin kinases in proteinopathy

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.

The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43