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List of works by Bin Zhan

2257: Vaccine efficacy and immunogenicity of recombinant WAP and CAP-1 proteins in AKR mice

scientific article published in September 2017

A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice

scientific article published on 08 January 2020

A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis

scientific article published on 10 September 2020

A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease

scientific article published on 18 February 2016

A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection

scientific article published on 30 May 2019

Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum

scientific article

Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects

scientific article published on September 2012

Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections

scientific article

An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection

scientific article published on 20 April 2009

Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration

scientific article

Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals

scientific article

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans

scientific article published on 16 September 2019

Ascaris Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice

scientific article published on 20 November 2018

Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis

scientific article published on 23 July 2013

Calling for rapid development of a safe and effective MERS vaccine

scientific article published on 12 June 2014

China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative

article

Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

scientific article

Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties

scientific article published on 02 February 2016

Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis

scientific article published on 30 July 2013

Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials

scientific article

Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen

scientific article published on 4 April 2012

Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis

scientific article published on 20 October 2016

Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice

scientific article

Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE.

scientific article published on August 2012

Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy

scientific article

Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24

scientific article

Identification of immunodominant antigens for the laboratory diagnosis of toxocariasis

scientific article published on October 2015

Identification, Characterization, and Structure of Tm16 from Trichuris muris

scientific article published on 14 August 2017

IgG Induced by Vaccination With Extracts Is Protective Against Infection

scientific article published on 09 November 2018

Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils

scientific article published on 08 October 2018

Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus

scientific article

Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis

scientific article published on 05 June 2017

Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice

scientific article published on 21 September 2018

Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative

scientific article

Protective effect of a prime-boost strategy with the Ts87 vaccine against Trichinella spiralis infection in mice

scientific article

Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection

scientific article published on 13 February 2020

Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16.

scientific article published on 31 January 2007

Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome

scientific article published on December 2012

SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice

scientific article published on 05 November 2020

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

scientific article

Schistosoma haematobium Extracellular Vesicle Proteins Confer Protection in a Heterologous Model of Schistosomiasis

scientific article published on 24 July 2020

Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis

scientific article (publication date: 9 March 2017)

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

scientific article

The Onchocerciasis Vaccine for Africa--TOVA--Initiative

scientific article

The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates

scientific article (publication date: 2012)

The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates

scientific article published on 27 September 2016

Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm

scientific article published on 28 August 2018

Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection

scientific article (publication date: April 2016)

Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms

scientific article

Vaccination with chimeric protein induces protection in murine model against ascariasis

scientific article published on 26 November 2020

Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs

scientific article published on 15 August 2005

Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

scientific article

Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model

scientific article

Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response

scientific article published on 14 July 2017

Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

scientific article

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