List of works - Bassem Sadek

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats

scientific article published on 30 March 2020

Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats.

scientific article published on 22 October 2015

Anticonvulsant and reproductive toxicological studies of the imidazole-based histamine H3R antagonist 2-18 in mice.

scientific article published on 19 January 2018

Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats

scientific article published on 03 May 2018

Anticonvulsive effect of nonimidazole histamine H3 receptor antagonists.

scientific article published in June 2014

Cherry-picked ligands at histamine receptor subtypes.

scientific article

Current Enlightenment About Etiology and Pharmacological Treatment of Autism Spectrum Disorder.

scientific article published on 16 May 2018

Drug-likeness approach of 2-aminopyrimidines as histamine H3 receptor ligands.

scientific article published on 19 September 2014

Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats

scientific article published on 20 February 2019

Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases

scientific article published on 27 June 2016

Influence of the Novel Histamine H3 Receptor Antagonist/Inverse Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha-Methylhistamine in C57BL/6 Mice

scientific article published on 12 September 2019

Non-imidazole histamine H3 receptor ligands incorporating antiepileptic moieties.

scientific article published on 6 March 2014

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

scientific article published on 21 August 2020

SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT(7) receptor ligands among phenylpiperazine hydantoin derivatives.

scientific article published on 18 March 2014

Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

scientific article published on 28 August 2020

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats

scientific article published on 29 October 2018

Studies on molecular properties prediction and histamine H3 receptor affinities of novel ligands with uracil-based motifs.

scientific article published on 6 September 2014

Synthesis and dual histamine H₁ and H₂ receptor antagonist activity of cyanoguanidine derivatives.

scientific article published on 15 November 2013

The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice

scientific article published on 03 June 2020

The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats

scientific article published on 12 February 2018

The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats

scientific article published on 12 October 2017

The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats

scientific article published on 14 November 2019

The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.

scientific article published on 11 October 2015

The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammmation in sodium valproate induced autism in mice

scientific article published on 30 July 2019

Therapeutic Potential of β-Caryophyllene: A Dietary Cannabinoid in Diabetes and Associated Complications

scientific article published on 28 September 2020

List of works by Bassem Sadek