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List of works by Demin Cai

A master regulator of cholesterol biosynthesis constitutes a therapeutic liability of triple negative breast cancer

scientific article published on 28 January 2020

Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-pro

scientific article published on 23 February 2017

Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.

scientific article

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice.

scientific article published on 12 August 2016

Butyrate stimulates adipose lipolysis and mitochondrial oxidative phosphorylation through histone hyperacetylation-associated β3 -adrenergic receptor activation in high-fat diet-induced obese mice.

scientific article published on 28 December 2016

Co-option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA-induced hepatic steatosis

scientific article published on 13 November 2020

Conjugated linoleic acid supplementation caused reduction of perilipin1 and aberrant lipolysis in epididymal adipose tissue ⬇️

scientific article published on May 15, 2012

Dietary Conjugated Linoleic Acid Modulates the Hepatic Circadian Clock Program <i>via</i> PPARα/REV-ERBα-Mediated Chromatin Modification in Mice

scientific article published on 15 October 2021

Dietary Fiber in Bilberry Ameliorates Pre-Obesity Events in Rats by Regulating Lipid Depot, Cecal Short-Chain Fatty Acid Formation and Microbiota Composition

scientific article published on 15 June 2019

Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions

scientific article published on 20 November 2014

Epigenetic and SP1-mediated regulation is involved in the repression of galactokinase 1 gene in the liver of neonatal piglets born to betaine-supplemented sows.

scientific article published in June 2016

Epithelial Heat Shock Proteins Mediate the Protective Effects of <i>Limosilactobacillus reuteri</i> in Dextran Sulfate Sodium-Induced Colitis

scientific article published on 07 March 2022

Erratum: Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

scholarly article published in Nature Medicine

Expression of hepatic miRNAs targeting porcine glucocorticoid receptor (GR) 3'UTR in the neonatal piglets under a maternal gestational betaine supplementation

scientific article

Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.

scientific article published on 31 August 2016

GR-mediated FTO transactivation induces lipid accumulation in hepatocytes via demethylation of m6A on lipogenic mRNAs

scientific article published on 09 March 2020

Gestational dietary betaine supplementation suppresses hepatic expression of lipogenic genes in neonatal piglets through epigenetic and glucocorticoid receptor-dependent mechanisms.

scientific article published on 19 October 2015

Hypermethylation of Sp1 binding site suppresses hypothalamic POMC in neonates and may contribute to metabolic disorders in adults: impact of maternal dietary CLAs.

scientific article

In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks

scientific article

In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.

scientific article published on 06 January 2017

Intravenous injection of microvesicle-delivery miR-130b alleviates high-fat diet-induced obesity in C57BL/6 mice through translational repression of PPAR-γ.

scientific article

Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets

scientific article published on 12 June 2015

Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets

scientific article published on 12 November 2015

Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.

scientific article published on 18 October 2016

Maternal Low-protein Diet Alters Ovarian Expression of Folliculogenic and Steroidogenic Genes and Their Regulatory MicroRNAs in Neonatal Piglets.

scientific article

Maternal dietary betaine supplementation modifies hepatic expression of cholesterol metabolic genes via epigenetic mechanisms in newborn piglets

article

Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway

scientific article published on 15 August 2015

Maternal protein restriction depresses the duodenal expression of iron transporters and serum iron level in male weaning piglets.

scientific article

Maternal protein restriction during gestation and lactation programs offspring ovarian steroidogenesis and folliculogenesis in the prepubertal gilts.

scientific article published on 28 April 2014

Nuclear Receptors in Hepatic Glucose and Lipid Metabolism during Neonatal and Adult Life.

scientific article published on 26 June 2016

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

scientific article published on 28 March 2016

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

scientific article published on 11 October 2019

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy

scientific article published on 9 September 2016

Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin modification in porcine liver organoids

scientific article published on 02 November 2020

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