List of works - Janne Koskimäki

A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease

scientific article published on 24 August 2019

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

scientific article published on 17 April 2019

Absorption, elimination and cerebrospinal fluid concentrations of nimodipine in healthy beagle dogs receiving human intravenous and oral formulation

scientific article published on 5 February 2015

Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial

scientific article published on 01 December 2019

Biomarkers of cavernous angioma with symptomatic hemorrhage

scientific article published on 20 June 2019

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

scientific article published on 15 November 2018

Common transcriptome, plasma molecules, and imaging signatures in the aging brain and a Mendelian neurovascular disease, cerebral cavernous malformation

scientific article published on 17 June 2020

Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes

scientific article published on 07 February 2019

Editorial for "Ensemble Learning for Early-Response Prediction of Antidepressant Treatment in Major Depressive Disorder"

scientific article published on 08 February 2020

Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model ⬇️

scientific article

Nimodipine activates TrkB neurotrophin receptors and induces neuroplastic and neuroprotective signaling events in the mouse hippocampus and prefrontal cortex.

scientific article published on 10 September 2014

Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma

scientific article published on 27 May 2020

Phantom validation of quantitative susceptibility and dynamic contrast-enhanced permeability MR sequences across instruments and sites

scientific article published on 12 September 2019

Phenotypic characterization of murine models of cerebral cavernous malformations

scientific article published on 26 June 2018

Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth

scientific article published on 02 May 2018

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease

scientific article published on 01 March 2019

Risk Factors for Recurrent Hematoma After Surgery for Acute Traumatic Subdural Hematoma

scientific article published on 10 January 2019

Subclinical imaging changes in cerebral cavernous angiomas during prospective surveillance

scientific article published on 03 April 2020

Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure

scientific article published on 01 June 2019

Symptomatic Brain Hemorrhages from Cavernous Angioma After Botulinum Toxin Injections, a Role of TLR/MEKK3 Mechanism? Case Report and Review of the Literature

scientific article published on 07 January 2020

Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations

scientific article published on 19 August 2019

Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH).

scientific article published on 11 April 2018

List of works by Janne Koskimäki