List of works - Rana Moubarak

A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

scientific article published on 04 November 2019

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.

scientific article published on 19 February 2013

Activation-induced cell death in T lymphocytes from multiple sclerosis patients

scientific article published on 16 April 2014

Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death. ⬇️

scientific article published on 12 February 2015

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways

scientific article published on 21 March 2016

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

scientific article published on 01 January 2020

FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.

scientific article published on December 2013

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration

scientific article (publication date: 21 October 2016)

FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification

scientific article

Identification and characterization of new isoforms of human fas apoptotic inhibitory molecule (FAIM).

scientific article published on 5 October 2017

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

scientific journal article

MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness

scientific article

SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L

scientific article published on 03 February 2020

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas.

scientific article published on 19 March 2015

The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins